The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $134,514 Project Grant to the Board of Regents of the University of Nebraska, operating as the University of Nebraska, to conduct research on "Collaborative Research: Ultrasound Driven Microbubble Clusters for Biomedical Applications" beginning May 1, 2024. The project aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation dynamics to understand how microbubble clusters can be navigated within narrow blood vessels using acoustic actuation. The research will leverage advanced computer simulations to assess the feasibility of this approach under physiological conditions and biocompatible acoustic power levels, providing a comprehensive understanding of the physical mechanisms governing microbubble cluster motion in blood vessels. In addition to the research activities, the project includes opportunities for training and research participation by undergraduate and graduate students from underrepresented groups, as well as public outreach through the University's Osher Lifelong Learning Institute.
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