Project Grant 2342257
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $1,000,000 in funding to Tufts University to study how a factor secreted from muscle regulates levels of neurotransmitter receptors in neurons that control movement in the roundworm Caenorhabditis elegans. The research aims to advance scientific understanding of how muscle releases factors that signal to the brain to control communication between neurons, which may provide...
- This $454,938 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research to define the impact of exercise on the aging nervous system. The project, led by Rutgers, The State University, will leverage the C. elegans worm model to characterize how regular exercise protects the nervous system against age-related dysfunction, including neuronal hyperactivity similar to brain aging in mammals. The research aims to elucidate the molecular...
- This federal Project Grant award of $2,358,537.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports a research project titled "Epigenetic Aging, Cognitive Function and Exercise in Older Adults" at the University of Pittsburgh. The project aims to investigate the impact of exercise on epigenetic aging and its relationship to cognitive function, brain health, and Alzheimer's disease biomarkers in non-cognitively impaired older adults. The award period runs from...
- The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $399,146 Project Grant to the Regents of the University of Michigan under the Engineering program (CFDA 47.041) to develop a bioreactor system for conducting research on the effects of microgravity and aging on neuromuscular function. The objectives are to evaluate force generation and reactive oxygen species production in tissue-engineered human nerve-muscle constructs,...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) in the amount of $665,118 supports a study to examine the neural mechanisms underlying the benefits of aerobic exercise for advanced Parkinson's disease (PD) patients with deep brain stimulation (DBS) implants. The research will enroll 51 advanced PD patients with DBS to assess the impacts of voluntary and forced aerobic exercise on motor, cognitive, and dual-task performance. Neural activity...
- This $120,276 federal Project Grant awarded by the National Science Foundation (NSF) under the STEM Education program (CFDA 47.076) will fund a collaborative research project to enhance episodic memory through the integration of real-world brain recording, stimulation, and perception data. The key objectives are to: Synchronize human experience data from various IoT sensors with neuronal activity recordings to understand how brain patterns relate to real-world experiences. Leverage...
- The National Science Foundation (NSF) is providing a $170,617 Project Grant under its Engineering program (CFDA 47.041) to the University of Illinois to advance the scientific study of brain functional changes after a stroke and pioneer a tailored rehabilitation strategy that fits each individual's needs. The 5-year project aims to combine different imaging methods to guide electrical brain stimulation that improves the recovery of movement for stroke patients, potentially benefiting over half a...
- This federal Project Grant award, funded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041), supports research to develop a machine intelligence system that can assess patient motivation, adapt the challenge level of therapeutic activities, and provide unobtrusive cues to promote compliance with prescribed exercise after a stroke. The $220,947 award to The Medical College of Wisconsin, Inc. will conduct fundamental research to create an explainable AI capable of...
- The National Science Foundation (NSF) awarded a $550,000 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to Georgetown University. The 5-year grant, effective April 1, 2025, supports research to understand how changes in the extracellular matrix surrounding synapses affect synapse stability and brain function. This work aims to uncover the mechanisms that preserve brain connectivity, with potential to inspire new strategies for addressing neurological disorders...
- This Project Grant award from the National Science Foundation's (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) program will provide $698,115 to the University of Southern California (USC) to investigate how brief social interactions can affect brain function and cognitive performance in older adults. The project will use advanced brain imaging techniques, such as functional MRI, to study how these interactions influence the brain's salience network and its connections to other...
This $715,500 federal Project Grant awarded by the National Science Foundation's (NSF) Engineering program will support research at the University of Illinois to investigate the relationship between exercise and cognitive health. The project aims to determine how muscle contraction during exercise may influence the activity and growth of cells in the hippocampus, the part of the brain involved in memory and learning. The research will conduct in vitro experiments culturing mouse muscle and hippocampal cells to evaluate the effects of exercise-induced biochemicals on cell contractility and neuron formation. The project will also analyze brain protein expression in exercising versus sedentary mice. The results may lead to a better understanding of pathologies like Alzheimer's disease, depression, and anxiety that impact the hippocampus. The project has a period of performance from June 1, 2024 to May 31, 2027 and does not involve any subawards.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $715.5k | 3/27/24 |