Project Grant 2327906

Award Date 2/1/24
Completion Date 1/31/28
Dollars Obligated $818K
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Greensboro, NC 27412, USA
Similar Awards
This $450,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research to identify novel genes and mechanisms involved in iron acquisition and accumulation in the ancient crop tef (Eragrostis tef). The overarching goal is to characterize genetic factors that allow tef, a nutrient-rich cereal, to accumulate high levels of bioavailable iron in its grains. The research will utilize CRISPR-Cas9 gene editing in tef to further study...
This $426,473 project grant awarded by the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences (CFDA 47.074 Biological Sciences) to Elizabeth City State University (ECSU) aims to improve the transformation and regeneration of recalcitrant plant species, particularly maize. The research will exploit a "morphogenic-based system" called GGB to better understand the molecular events leading to successful plant regeneration from differentiated tissue. This...
This $959,997 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports a collaborative research project at Cold Spring Harbor Laboratory (CSHL) to investigate morphogenic-based mechanisms for improving plant regeneration and transformation methods. The key objectives are to: Provide a thorough understanding of the molecular events underlying successful plant regeneration from differentiated tissue using maize lines expressing genes...
This federal Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) provides $699,870 to the Donald Danforth Plant Science Center to develop simplified and efficient genetic modification technologies applicable across economically important grass and cereal crops. The 3-year project aims to leverage recent advances in plant regeneration from leaf tissues to adapt methods for use in crops like maize, sorghum, wheat, and biofuel grasses. The goal is to...
This $998,790 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will support enhancing global plant transformation capacity through research, training, and partnerships led by Boyce Thompson Institute For Plant Research Inc. Over a three-year period, the grantee will establish a global research coordination network to collectively address challenges to plant genetic engineering and gene editing efficiency. The network aims to facilitate...
The National Science Foundation (NSF) Division of Integrative Organismal Systems awarded a 4-year, $2,670,305 Project Grant titled "TRTECH-PGR: REPROGRAMMING THE PLANT CELL WITH TRANSCRIPTION FACTORS" under the Biological Sciences federal grant program (CFDA 47.074). This project aims to systematically assess the effects of ectopically expressing thousands of maize transcription factors on gene expression and physiological responses in plant tissues. The research will use...
This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $1,088,678 to Rutgers, The State University to conduct collaborative research on improving the methods for transformation and regeneration of recalcitrant plant species, with a focus on maize. The key objectives are to develop a thorough understanding of the molecular mechanisms underlying successful plant regeneration, and to exploit this knowledge to improve transformation...
This Project Grant award from the U.S. Department of Agriculture's (USDA) Agriculture and Food Research Initiative (AFRI) program, CFDA 10.310, will support research at Oregon State University to engineer improved Agrobacterium strains for more efficient plant genetic engineering. The $225,000 award, with a performance period from July 2024 to July 2026, aims to develop a toolkit for modifying Agrobacterium strains, both commonly used and novel wild-type strains, to enhance the efficiency and...
This $668,494 Project Grant awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research to systematically identify and characterize previously undetected open reading frames (ORFs) in four model plant species: Arabidopsis, tomato, rice, and maize. The project will leverage advanced experimental and computational techniques to discover these "noncanonical" ORFs, which can reveal new ways plants use proteins and control gene activities....
This $1,211,545 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop highly efficient and robust prime editing (PE) systems in rice, tomato, and poplar plants. The project will optimize PE proteins, improve guide RNA structure and expression, and modify plant DNA repair mechanisms to increase PE efficiency. The goal is to create next-generation PE tools for precise genome editing of both monocot and dicot plants, facilitating...

This $818,000 Project Grant was awarded by the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) to the University of North Carolina at Greensboro (UNC-G) to develop efficient genetic transformation techniques for the orphan crop tef (Eragrostis tef) and its wild relative Indian lovegrass (E. pilosa).

The key objectives are to: 1) Develop an efficient Agrobacterium-mediated transformation method for diverse tef genotypes to enable trait improvement research, and 2) Establish a transformation system for the wild E. pilosa, which has desirable traits like adaptation to wider environments and lodging tolerance that could benefit tef breeding. The project will leverage recent advances in using maize embryogenic regulator genes to improve transformation efficiency in recalcitrant monocot species like tef. It will also provide training opportunities for minority students, a postdoctoral researcher, and a visiting scientist from Ethiopia, where tef is a critically important staple crop. The resources developed, including publications, protocols, workshops, and websites, will be freely shared with the broader scientific community.

Generated 8/13/24, 4:58 AM