The National Science Foundation awarded a $750,000 Project Grant to the University of Missouri System under the Technology, Innovation, and Partnerships federal grant program (CFDA 47.084) to develop rapid detection technologies and decision support systems to mitigate food supply chain threats from Salmonella contamination. The one-year project will investigate multiple transformative sensing technologies, including surface enhanced Raman spectroscopy sensors, impedance-based biosensors, and...
This $199,997 federal Project Grant, awarded by the National Science Foundation's Engineering program (CFDA 47.041), aims to improve the stability and sensitivity of a heat-resistant version of the CRISPR-Cas13 enzyme for rapid and accurate detection of disease-causing RNA. The collaborative research project between William Marsh Rice University and its partners will leverage mechanism-based protein engineering and electrochemical devices to generate next-generation RNA detection tools for...
The National Science Foundation awarded a $199,999 Project Grant under the Engineering (CFDA 47.041) program to The Trustees of the University of Pennsylvania to develop a next-generation RNA detection tool for infectious disease diagnosis. The project aims to engineer a thermostable version of the CRISPR-Cas13 enzyme to improve its stability and sensitivity for field applications. By combining the enhanced Cas13 enzyme with advanced electrochemical devices, the researchers will create an...
This $430,785 National Science Foundation (NSF) CAREER award to the Regents of the University of California at Riverside (UC Riverside), awarded under the NSF Engineering program (CFDA 47.041), is focused on developing novel CRISPR-based biosensing technologies for the ultra-accurate detection of disease-related single nucleotide polymorphisms (SNPs). The central goals of the 5-year project are to: 1) enable ultra-accurate SNP detection using a CRISPR-Cas14 biosensor, 2) design a ratiometric SNP...
This National Science Foundation Project Grant of $180,493 will support the development of an ultrasensitive point-of-care diagnostic system using clustered regularly interspaced short palindromic repeats (CRISPR) technology for early disease detection without pre-amplification of viral genomes. Funded under the NSF's Office of Integrative Activities program (CFDA 47.083), which enhances STEM competitiveness through capacity building and broadening participation, this 24-month project will...
This Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture will fund research at Tennessee State University from April 1, 2023 through March 31, 2026 in the amount of $595,249. The grant is being awarded under the 1890 Institution Capacity Building Grants program (CFDA #10.216), which aims to build research and teaching capacity at 1890 land-grant institutions. Under this award, Tennessee State University will screen cyanobacterial extracts and...
Nanospy Inc. received a $256,000 Project Grant award from the National Science Foundation Division of Industrial Innovation on August 15, 2021 to develop handheld graphene-based sensors for rapid detection of Salmonella species in food processing facilities. The award is part of the Engineering program (CFDA 47.041) administered by NSF, which seeks to improve quality of life and economic strength through engineering research and innovation. Under the grant, Nanospy will design portable sensors...
This National Science Foundation Project Grant, funded under the Engineering program (CFDA 47.041), aims to improve the stability and sensitivity of a heat-resistant version of the CRISPR-Cas13 enzyme for accurate and robust detection of disease-causing RNA. The $200,000 award, effective November 1, 2024 through October 31, 2027, supports the University of Connecticut's efforts to engineer the Cas13 enzyme for enhanced thermostability, protease resistance, and target sensitivity. The...
The National Science Foundation awarded a $497,100 Project Grant to Tennessee State University under the Biological Sciences federal grant program (CFDA 47.074) for the period of September 1, 2022 through August 31, 2025. The grant will support research to better understand how legumes perceive peptides during root nodule symbiosis with bacteria. The researchers will use CRISPR-CAS9 gene editing and existing mutant lines in the model legume Medicago truncatula to develop an in-house collection...
This $256,000 Project Grant from the National Science Foundation's Division of Industrial Innovation, under the Engineering program (CFDA 47.041), funds the development of a rapid, simple, and low-cost Salmonella detection and quantification test. Secure Food Solutions, Incorporated will optimize a multi-layer 96-well microplate method to demonstrate 90% sensitivity and specificity for Salmonella in raw poultry and processing environment samples within 15 hours without pre-enrichment. They...