The University of Colorado received a $111,471 Project Grant award from the National Science Foundation Division of Information and Intelligent Systems on September 1, 2021 to support research concluding on November 30, 2021. The grant funded collaborative research to accelerate synthetic biology discovery and exploration through knowledge integration under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). This program supports investigator-initiated...
Colorado State University will provide research, education, and outreach services under a $622,699 Project Grant from the National Science Foundation Division of Integrative Organismal Systems. The grant falls under the NSF Biological Sciences program (CFDA 47.074) and aims to facilitate the prediction and validation of plant enzyme functions through three key activities. First, CSU will deposit published plant enzyme activities into public databases to support computational function...
This three-year, $376,264 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research to develop new genetically engineered biological circuits and sensors. The University of Colorado Boulder team, led by The Regents of the University of Colorado, aims to harness plant hormone receptors to rapidly design genetic circuits controlled by user-specified ligands. They will engineer novel plant-derived chemical sensors that can recognize...
This $1,000,000 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program supports research by the University of California, San Francisco (UCSF) to design, build, and test synthetic signaling systems built from computationally-designed de novo protein components. The goal is to develop stable, tunable, and modular signaling systems capable of precisely controlling biological processes, with applications in biotechnology such as engineered cells for...
This Project Grant award of $300,000 from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) supports the development and experimental validation of computational tools for simulation-guided design of DNA nanostructures and molecular systems. The project aims to integrate high-level and low-level computational models to enable more powerful and user-friendly multiscale modeling frameworks for DNA nanotechnology. Key objectives include parameterizing coarse-grained...
This $376,301 project grant awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at the University of Rochester aimed at developing a practical approach for controlling and stabilizing microbial communities. The project leverages plasmid conjugation to dynamically balance microbial growth rates and composition, creating programmable microbial populations that can maintain stability across diverse conditions. Key objectives include computational...
This Project Grant award of $520,720 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support research to develop new tools for incorporating emerging models of genetics into genetic mapping, prediction, and simulation. The research, conducted by Colorado State University, aims to better integrate molecular and cellular biology knowledge into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype...
This $120,449 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) will support a coordinated three-campus PhD training and research program in synthetic biology between the University of Tennessee, University of Florida, and Purdue University. The universities will hold three virtual workshops, one hosted by each institution, to design an interuniversity graduate research certificate in synthetic biology. The certificate program will include online...
This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
This $1,686,589 project grant, awarded by the National Science Foundation (NSF) under its STEM Education (CFDA 47.076) program, aims to engage youth and families from underserved communities in the emerging field of synthetic biology. The project will develop culturally responsive, hands-on "biomaker" activities that use living biological materials, such as genetically modified microbes, mycelium, and algae, to provide accessible introductions to synthetic biology. An initial group...