The National Science Foundation (NSF) Division of Integrative Organismal Systems awarded a $277,978 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of California, Berkeley. The 3-year grant, beginning on Sep 1, 2023, aims to develop new tools and resources to enable more efficient gene editing in maize, the world's most produced crop. Specifically, the project will generate maize lines that constitutively express the Cas9 gene editing enzyme and engineer...
This $322,020 Project Grant award from the National Science Foundation's (NSF) Division of Integrative Organismal Systems will support collaborative research at the University of California, Davis (UC Davis) to develop improved methods for CRISPR/Cas9-based gene editing in maize. The key objectives are to generate maize lines expressing high levels of Cas9 nuclease and to engineer and optimize viral vectors to efficiently deliver guide RNAs for both somatic and heritable gene editing. This...
The National Science Foundation awarded a $307,400 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Missouri System to develop epigenetic editing tools for improving crop plants. The project aims to expand the capabilities of genome editing by enabling targeted changes in gene expression, rather than just DNA sequence, to generate novel traits in important crops like rice and tomato. Key objectives include adapting the epigenetic editing approach...
This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research on improving transformation and regeneration methods for maize and other recalcitrant plant species. The $524,852 award to Virginia Polytechnic Institute & State University aims to provide a thorough understanding of the molecular events leading to successful plant formation from differentiated tissues. The goal is to develop new strategies for enhancing...
This federal Project Grant award of $1,192,499.00 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research by the Donald Danforth Plant Science Center in Missouri to develop epigenetic editing tools for crop improvement. The key objectives of this 4-year project are to: 1) Expand epigenetic editing technologies to other crop species beyond cassava, such as rice and tomato, to enable disease resistance; 2) Demonstrate additional applications of...
This National Science Foundation (NSF) Project Grant, awarded under the Integrative Activities program (CFDA 47.083), will support collaborative research at Kansas State University to identify the genetic basis of plant regeneration, specifically focusing on maize. The $400,000 award will fund the project from September 1, 2023 to August 31, 2027. The primary goal is to better understand the genetic mechanisms controlling plant cell proliferation and growth, which are critical for successful...
This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $426,473 to Elizabeth City State University (ECSU) aims to improve maize regeneration and transformation methods. The project will leverage maize lines expressing morphogenic genes to gain a better understanding of the molecular processes driving plant regeneration. This knowledge will support the development of new strategies to enhance transformation efficiency in maize and other...
This $959,997 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research at Cold Spring Harbor Laboratory (CSHL) to understand the molecular mechanisms underlying plant regeneration, with a focus on maize. The goal is to identify key genes and pathways that regulate the ability of plant cells to reprogram and develop into new plants, which is particularly challenging for some crop species. The research will exploit a...
This $1,228,250 National Science Foundation project grant supports research into the B chromosome of maize and its impact on genomic processes. Led by the University of Missouri System, the three-year award aims to advance understanding of properties that have allowed the extra, non-essential B chromosome to persist in maize for millions of years despite providing no benefit to the plant. The interdisciplinary team will conduct genetic and molecular analysis to learn the nature of properties...
This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $2,379,217 to the Donald Danforth Plant Science Center from March 1, 2022 to February 28, 2025. The grant supports research to develop targeted DNA integration techniques in plants. Specifically, the Center and its sub-awardees—the University of South Carolina Aiken Campus and University of Missouri—will work to engineer hyperactive versions of the Pong transposase proteins and...