Project Grant 2105167
Award Date
6/1/21
Completion Date
5/31/25
Dollars Obligated
$805K
Federal Agency
Division of Molecular and Cellular Biosciences
Awardee
Baylor University (C6T9BYG5EYX5)
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Waco, TX 76798, USA
Similar Awards
Baylor University received a $1.1 million Project Grant award from the National Science Foundation under the Biological Sciences program (CFDA 47.074) for the period of March 1, 2022 through February 28, 2027. The award will support research into investigations of dynamic DNA recognition and processing during eukaryotic nucleotide excision repair. The research aims to obtain detailed molecular and structural understanding of critical steps in the initiation of nucleotide excision repair...
Baylor University was awarded a $426,000 Project Grant from the National Science Foundation Division of Chemistry to directly quantify the thermodynamic cooperativities and conformations of single-strand DNA binding proteins from July 1, 2021 to June 30, 2024. The award is being used to support research under the NSF's Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national scientific enterprise through...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded Rice University a $373,174 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to conduct research toward developing lifelike synthetic cells through engineered control of DNA replication from August 15, 2021 to July 31, 2024. The Biological Sciences program aims to advance biological knowledge and understanding of major problems to strengthen the nation's scientific enterprise....
This Project Grant from the National Institutes of Health's National Institute of General Medical Sciences, under the Biomedical Research and Research Training program (CFDA 93.859), provides $754,986 to Baylor University from September 1, 2022 through August 31, 2025. The grant supports research into the mechanisms of DNA damage processing and initiation of nucleotide excision repair. Specifically, the grant will fund experiments using cryo-electron microscopy, time-resolved fluorescence...
This $2,285,694 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at Tufts University to study the relationship between DNA replication and tandem repeat instability. The grantee will combine genetic assays and single-cell live microscopy analysis in a model system to understand how repeat length changes during replication. This dual approach will examine how a repeat's length, propensity to form DNA structures, and orientation...
The National Science Foundation (NSF) awarded a $1,100,000 Project Grant (CFDA 47.074 - Biological Sciences) to the University of Arkansas for Medical Sciences (UAMS) to study the replication of G-quadruplex DNA by translesion polymerases. This project aims to determine how proteins are recruited to sites of DNA replication and function together to copy G-quadruplex DNA structures, which can act as barriers to accurate genome replication. The research will elucidate the molecular mechanisms...
This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program provides $246,424 to the University of California, Santa Barbara (UCSB) to research the initiation of recombination at DNA double-strand breaks. The 5-year project, running from March 2025 to February 2030, aims to leverage novel methods to understand how cells choose different DNA repair mechanisms, with a focus on recombination. The research will define key steps in the recombination...
This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program will provide $950,000 to Texas A&M University from June 1, 2025 to May 31, 2029. The project will investigate how the enzyme thymine DNA glycosylase, a key player in the DNA demethylation pathway, is targeted to specific methyl groups throughout the genome. This research aims to improve understanding of how DNA methylation landscapes are established and maintained under...
This National Science Foundation (NSF) federal Project Grant award under the Biological Sciences program (CFDA 47.074) is funding the University of Illinois to construct a new type of self-replicating synthetic cell system. The $448,355 award from June 1, 2024 to May 31, 2027 supports the development of engineered synthetic cells that can grow, divide, and replicate their genetic information using nucleic acids as both structural and genetic components. The project aims to investigate the...
The University of New Mexico was awarded a $414,071 project grant from the National Science Foundation Division of Molecular and Cellular Biosciences under the Biological Sciences federal grant program (CFDA 47.074). The grant will support collaborative research toward developing lifelike synthetic cells through engineered control of DNA replication from August 15, 2021 to July 31, 2024. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the...