This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $246,424 supports research to define how human cells control the initiation and early steps of recombination at DNA double strand breaks. The project leverages novel methods to understand how cells choose different DNA repair mechanisms, with a focus on recombination, which maintains encoded genetic information. The research will address key questions around recombination activation, the role of the DNA repair regulatory kinase ATR, and the involvement of DNA repair factors. This work has broad implications for fields like gene editing, cancer treatment, and personalized medicine. Additionally, the project will provide training and research experiences to junior transfer college students to improve academic success and retention in STEM fields. The award was made to the University of California, Santa Barbara and is set to run from March 1, 2025 through February 28, 2030.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $246.4k | 2/13/25 |