This $1.3 million project grant from the US Department of Agriculture's National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310) supports establishing a cattle and sheep pan-epigenome through December 2025. The University of Vermont is leading efforts to comprehensively characterize epigenomic conservation and diversity in multiple breeds of cattle and sheep by examining DNA and RNA methylation, histone modifications, open chromatin, and chromatin accessibility in the liver, muscle, and prefrontal cortex. Comparative epigenomics will identify orthologous regions of the bovine and ovine epigenomes harboring conserved epigenetic modifications and variants. Oklahoma State University and the University of Idaho are receiving sub-awards to support establishing the pan-epigenome for cattle and sheep. Cataloging epigenetic diversity across breeds is intended to further understanding of how genomes, epigenomes, and gene products affect important phenotypes to improve prediction of traits and breeding strategies.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $1.3m | 11/15/21 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
AWD00000804SUB00000584S | University Of Missouri System | Project Grant 20226701636216 | $892.1k | 6/28/24 | |
AWD00000804SUB00000321S | Regents Of The University Of Idaho | Project Grant 20226701636216 | $145.0k | 3/8/22 | |
AWD00000804SUB00000320S | Oklahoma State University | Project Grant 20226701636216 | $145.0k | 3/8/22 |