Project Grant 20226701544185

Award Date 1/1/25
Completion Date 12/31/25
Dollars Obligated $533K
Federal Grant Program
10.310
Assistance Type
Project Grant
Place of Performance
Urbana, IL 61801, USA
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This $532,838.06 federal Project Grant award from the U.S. Department of Agriculture's Agriculture and Food Research Initiative (CFDA 10.310) seeks to develop novel antimicrobial peptide therapeutics to combat Avian Pathogenic E. coli (APEC) infections in poultry. APEC is a major bacterial pathogen causing substantial economic losses to the U.S. and global poultry industry.

The primary awardee, the University of Illinois, will evaluate the efficacy, safety, and applicability of two previously identified antimicrobial peptides (P-1 and P-2) in chicken drinking water. The goal is to elucidate the mechanism of action of these peptides and advance them as alternative therapeutics to antibiotics for controlling APEC infections in poultry. The award period is from Jan 1, 2025 to Dec 31, 2025.

Under a sub-award, The Ohio State University will collaborate on the research to develop these antimicrobial peptides as novel treatments for APEC. This sub-award aims to enhance the control of APEC infections and promote sustainable poultry production.

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