Project Grant 20246701642415

Award Date 7/1/24
Completion Date 6/30/27
Dollars Obligated $650K
Federal Grant Program
10.310
Assistance Type
Project Grant
Place of Performance
Stillwater, OK 74078, USA
Similar Awards
This USDA National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) Project Grant in the amount of $180,000 awarded to Oklahoma State University (OSU) aims to identify antimicrobial metabolites and immune-boosting mechanisms produced by a commensal bacterium that can mitigate Clostridium perfringens-induced necrotic enteritis in poultry. The project has two primary objectives: 1) to identify major antibacterial and host defense peptide-inducing metabolites...
Oklahoma State University will receive $300,000 from the National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive federal grants program to study methods for mitigating necrotic enteritis in poultry. Specifically, the university will compare the gut microbiota of necrotic enteritis-resistant and susceptible chicken breeds when subjected to the disease. Fecal microbiota from resistant and susceptible chickens will be transplanted into naive...
The U.S. Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) awarded a $650,000 Project Grant under the Agriculture and Food Research Initiative (CFDA 10.310) to the Division of Agriculture of the University of Arkansas. The award period is from July 1, 2024 to June 30, 2028. The project aims to develop effective interventions to mitigate necrotic enteritis (NE), a prevalent poultry disease causing estimated $6 billion in annual losses worldwide. Key objectives...
The U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) awarded a $648,154 Project Grant under the Agriculture and Food Research Initiative (AFRI) competitive grants program to the Agricultural Research Service (ARS), a component of the Government of the United States. The grant supports the development of a multi-strain electron beam (e-beam)-killed vaccine to control Clostridium perfringens-induced necrotic enteritis (NE) and Mycoplasma gallisepticum-induced...
Oklahoma State University was awarded a $650,000 Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (AFRI) federal grant program. The grant will fund research to develop epigenetic compounds as next-generation antibiotic alternatives for livestock use. Specifically, the researchers will further screen combinations of epigenetic compounds to identify those highly potent at inducing host...
This $532,838.06 federal Project Grant award from the U.S. Department of Agriculture's Agriculture and Food Research Initiative (CFDA 10.310) seeks to develop novel antimicrobial peptide therapeutics to combat Avian Pathogenic E. coli (APEC) infections in poultry. APEC is a major bacterial pathogen causing substantial economic losses to the U.S. and global poultry industry. The primary awardee, the University of Illinois, will evaluate the efficacy, safety, and applicability of two previously...
This $650,000 Project Grant awarded by the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) CFDA 10.310 program aims to evaluate the safety and efficacy of a genetically engineered Bacillus subtilis probiotic strain in reducing Salmonella colonization in broiler chickens. The primary awardee, the Regents of the University of Michigan, will develop a B. subtilis strain that secretes Salmonella-neutralizing nanobodies to directly...
The Agricultural Research Service was awarded $500,000 under the Agriculture and Food Research Initiative (AFRI) competitive grants program administered by the United States Department of Agriculture National Institute of Food and Agriculture. The three-year project grant will fund research at the Southeast Area location in Stoneville, MS to identify the functional pathways by which avian pathogenic Escherichia coli infection occurs in broiler chickens. The research aims to provide mechanistic...
This $299,322 Project Grant award to Auburn University was issued by the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The objective is to determine the impact of antimicrobial use (AMU) in poultry production on microbial diversity, antimicrobial resistance (AMR) genes, and horizontal gene transfer in the environment. The research will compare AMR levels and animal health outcomes between antimicrobial-free...
This $300,000 Project Grant was awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The objective is to develop and implement effective mitigation strategies at the production level to limit Salmonella colonization in chickens and reduce the transmission of Salmonella to poultry products and humans. The grant will fund research to evaluate the efficacy of combining...

The U.S. Department of Agriculture (USDA) awarded a $650,000 Project Grant under the Agriculture and Food Research Initiative (CFDA 10.310) to Oklahoma State University (OSU) to conduct research on developing an antibiotic-free approach to combat necrotic enteritis (NE) in poultry. Specifically, the project will screen additional commensal bacteria for their ability to inhibit the growth of Clostridium perfringens, the bacterium that causes NE, and induce host defense peptide synthesis to enhance innate immunity. Lead bacterial candidates will be further evaluated for their protective efficacy in NE-infected chickens, and the mechanism of action for the most effective bacterium will be studied. Upon completion by June 30, 2027, the project aims to identify several commensal bacteria that can effectively mitigate NE and reveal their major mechanism of action, facilitating the development of an innovative antibiotic-free solution to address this economically devastating poultry disease.

Generated 1/28/25, 8:39 AM