Cooperative Agreement U54CA302426
- This $5,041,790 cooperative agreement award from the National Cancer Institute (NCI), under the Cancer Centers Support Grants program (CFDA 93.397), will fund research projects at the University of California, San Francisco (UCSF) to improve cancer health disparities. The key products and services to be delivered include: Three translational cancer health disparities research projects focused on meningioma, prostate cancer, and breast cancer. The projects aim to evaluate the interplay of...
- This National Cancer Institute (NCI) Project Grant award under the Cancer Biology Research program (CFDA 93.396) provides $456,103 in funding to The Feinstein Institutes for Medical Research to develop integrated risk models for endometrial cancer. The project aims to enhance early detection of endometrial cancer by determining the burden of rare genetic risk factors and creating predictive models that integrate genetic and non-genetic factors such as BMI, diabetes, and PCOS. The research will...
- This Project Grant award from the National Cancer Institute (CFDA 93.398 Cancer Research Manpower) provides $183,309 to Wayne State University to investigate the relationship between socioeconomic factors, molecular subtypes of endometrial cancer, and survival outcomes in a population-based cohort of women diagnosed with endometrial cancer in metropolitan Detroit. The 5-year project aims to leverage comprehensive data from the Detroit Research on Cancer Survivors (ROCS) cohort to examine how...
- This Cooperative Agreement award for $639,882, funded by the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396), supports research at the University of North Carolina at Chapel Hill to elucidate the molecular mechanisms of metastasis organ tropism in breast cancer. The key objectives are to: Identify molecular determinants of lung and liver organ-specific metastasis using a comprehensive dataset of human primary tumors and metastases, as well as genetically...
- This Project Grant award from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) provides $132,825 to the Sloan-Kettering Institute for Cancer Research to develop and validate prognostic models for Black women with endometrial cancer following hysterectomy. The key products and services to be delivered include: Building a robust prognostic tool tailored for Black endometrial cancer patients to predict 3- and 5-year post-hysterectomy survival using clinical and epidemiological...
- This federal Project Grant award from the Defense Health Agency provides $1,555,000.00 to the University of North Carolina at Chapel Hill to support their research project titled "TARGETING OBESITY VIA DIET AND DRUGS FOR THE TREATMENT OF ENDOMETRIAL CANCER". The award is funded under the Military Medical Research and Development (CFDA 12.420) federal grant program, which supports advanced biomedical research initiatives focused on transforming healthcare for military personnel and...
- This Project Grant award from the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research) for $2,801,881 aims to improve clinical management and outcomes for patients with endometrial cancer (EC) and pre-cancerous atypical endometrial hyperplasia (AEH). The University of New Mexico Health Sciences Center, the awardee, will work to: 1) prevent the transition of AEH to EC, 2) prevent the progression of EC after initial treatment, and 3) prevent treatment-associated breast...
- This $165,012 Project Grant, awarded by the National Institute on Minority Health and Health Disparities (NIMHD) under the Minority Health and Health Disparities Research (CFDA 93.307) program, supports the development and feasibility testing of a multi-level, community-engaged intervention to increase access to cervical cancer screening using HPV self-collection (HPVSC) outreach among high-risk, rural women in North Carolina. The project aims to: 1) establish a Community Advisory Board (CAB) to...
- This Project Grant award, provided by the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393), will fund a study to evaluate the impact of social determinants of health (SDOH) on early-onset colorectal cancer (EOCRC) diagnosis, treatment delays, and survival, with a focus on underserved populations in Kentucky and Georgia. The $192,610 award will support a 2-year epidemiologic study that aims to elucidate the relationship between SDOH measures and...
- This federal Project Grant award, totaling $477,869.00, was provided by the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395). The grant aims to develop tailored, multilevel cervical cancer interventions for ethnically diverse Black women, including African American women and Black African immigrant women. The key objectives are to: 1) identify multilevel determinants of routine cervical cancer screening and follow-up adherence among these populations,...
This federal Cooperative Agreement award from the National Cancer Institute (CFDA 93.397 - Cancer Centers Support Grants) provides $2,255,110.00 to the University of North Carolina at Chapel Hill to establish the Cancer Health Disparities SPORE in Endometrial Cancer. The primary objective of this 5-year project is to investigate the biological and social factors driving health disparities in endometrial cancer, which is increasing in frequency and mortality. The research team will leverage three unique patient cohorts, including the Carolina Endometrial Cancer Study, as well as pre-clinical mouse and organoid models to study key factors such as epigenetic aging, microbiome, innate immunity, metabolic reprogramming, and allostatic load. The goal is to define how these social and biological factors contribute to more aggressive endometrial cancer behavior and worse outcomes, in order to inform interventions that address cancer health disparities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.3m | 9/17/25 |