This Project Grant award, funded by the National Cancer Institute under the Cancer Research Manpower program (CFDA 93.398), supports the development and external validation of prognostic models to inform tailored adjuvant therapy decisions for Black women diagnosed with endometrial cancer following hysterectomy.
The $132,825 grant, awarded on February 13, 2025, will enable researchers at the Sloan-Kettering Institute for Cancer Research in New York to: 1) build and validate a prognostic tool using clinical and epidemiologic factors to predict 3- and 5-year survival for Black endometrial cancer patients post-hysterectomy, 2) assess the utility of adding molecular subtypes to the prognostic model, and 3) develop biomarker-based prognostic tools for both Black and White endometrial cancer patients. This research aims to address significant disparities in endometrial cancer incidence, mortality, and treatment outcomes for Black women. The resulting prognostic tools are intended to support clinical decision-making and improve cancer care for this underserved population.
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