Cooperative Agreement U01GH002150

This Cooperative Agreement award from the National Cancer Institute (NCI), under the federal grant program "Cancer Detection and Diagnosis Research" (CFDA 93.394), aims to develop a point-of-care HPV DNA test for cervical cancer screening in Mozambique. The total award is $585,943, with a performance period from September 1, 2024 to August 31, 2029. The key objectives are to: 1) Adapt existing extraction-free, multiplexed, isothermal nucleic acid amplification assays to detect 8...

This federal Cooperative Agreement award from the National Cancer Institute (NCI), under the Cancer Cause and Prevention Research (CFDA 93.393) program, provides $592,027 to Northwestern University to develop and validate a point-of-care molecular diagnostic test for active hepatitis C virus (HCV) infection. The project aims to create a portable, low-cost device that can rapidly diagnose active HCV by detecting viral RNA, eliminating the need for two-step serologic and laboratory-based...

This Project Grant award from the John E. Fogarty International Center (CFDA 93.989 - International Research and Research Training) provides $108,237 to Mbarara University of Science and Technology in Uganda to develop and assess the feasibility of a diagnostic tool for post-tuberculosis (TB) lung disease that can be deployed in primary healthcare settings. The key objectives are to: (1) create and validate a clinical diagnostic algorithm for post-TB lung disease, (2) conduct qualitative...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to optimize the implementation of digital x-ray technology with computer-aided detection (CAD) for community-based tuberculosis (TB) screening in sub-Saharan Africa. The $198,720 award will fund research to evaluate two novel screening strategies against the current standard approach: individually adjusting the CAD...

This Project Grant award in the amount of $431,712, funded by the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to improve HIV testing among children under five in rural Uganda. The primary goal is to engage with traditional healers to facilitate HIV counseling and testing via oral swab antigen tests for this vulnerable pediatric population. The award supports two key activities: 1) determining barriers and...

The National Center for Advancing Translational Sciences (NCATS), under CFDA 93.350, has awarded a $324,962 Project Grant to Tetmedical, Inc. to develop a technology for rapid, point-of-care and at-home testing of liver enzyme levels. The goal is to enable convenient and timely monitoring of drug-induced liver injury (DILI) and other sources of liver damage. The project aims to optimize tethered enzyme assays for detecting aspartate aminotransferase (AST) and alanine aminotransferase (ALT),...

This federal Project Grant award of $909,750.00, awarded by the Centers for Disease Control and Prevention (CDC) under the Investigations and Technical Assistance program (CFDA 93.283), supports the development of a two-minute rapid assay platform for point-of-care diagnosis. The awardee, Kephera Diagnostics LLC, is a for-profit limited liability company that specializes in innovative diagnostic solutions for infectious diseases, particularly neglected tropical diseases and parasitic infections....

This Project Grant award of $743,488.00 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA Program 93.865 Child Health and Human Development Extramural Research, aims to examine the mechanisms and optimization of malaria chemoprevention strategies to improve birth outcomes in Africa. The research objectives are to: 1) characterize the mechanisms mediating the effects of sulfadoxine-pyrimethamine (SP) and dihydroartemisinin-piperaquine...

This Cooperative Agreement award of $450,000.00 from the U.S. Centers for Disease Control and Prevention (CDC) under the Global AIDS program (CFDA 93.067) aims to advance the sustainable implementation of high-quality HIV services in Kisumu County, Kenya under the President's Emergency Plan for AIDS Relief (PEPFAR). The award, with a performance period from January 1, 2025 to September 29, 2029, will support technical assistance, service delivery, and capacity-building activities focused on...

This Cooperative Agreement award from the National Cancer Institute (NCI), under the Cancer Cause and Prevention Research (CFDA 93.393) program, aims to develop and evaluate an evidence-based, behavioral cervical cancer screening intervention for women living with HIV in Ghana. The $511,959 award to Baylor University will fund a hybrid effectiveness-implementation trial to integrate and scale up a home-based HPV self-sampling and communication model intervention called HOPE. The project seeks to...