Cooperative Agreement U01DD001075

Federal Grant Award Summary Vanderbilt University received a $2.96 million Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) awarded September 19, 2025, with completion scheduled for August 31, 2029. The project develops a multimodal diagnostic tool combining digitally stained white light cystoscopy (DSWLC) with polarization-sensitive optical coherence tomography (PS-OCT) to improve detection of urothelial carcinoma in situ...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $398,487 Project Grant (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to Vanderbilt University to develop and validate a gaze-based training system for endoscopic kidney stone surgery. The project aims to create an eye gaze-based guidance system that can improve surgeon training and stone visualization during endoscopic kidney stone procedures, which currently...

Federal Grant Award Summary Vanderbilt University received a $1,000,028 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) to translate near infrared autofluorescence (NIRAF) technology for pediatric endocrine neck surgeries. The project, which commenced September 1, 2025, and concludes August 31, 2027, aims to reduce hypocalcemia complications following pediatric...

This $1,432,794 federal Project Grant award, issued by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, supports a research project at Vanderbilt University Medical Center (VUMC) titled "Gene Expression Analysis of Circulating Tumor Cells: A Next-Generation Biomarker to Predict Immunotherapy Response in Metastatic Clear Cell Renal Cell Carcinoma". The 4-year project, with a start date of September 15, 2024 and end date of September...

Federal Grant Award Summary Vanderbilt University Medical Center received a $859,980 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded on August 22, 2025, with completion targeted for June 30, 2030. This award supports the development of kidney-targeted adeno-associated virus (AAV) vectors for gene therapy to address the significant therapeutic gap...

Federal Project Grant Award Summary Vanderbilt University Medical Center received a $590,565 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded September 1, 2025, with a completion date of May 31, 2030. The award funds the development of an engineered human ductus arteriosus (DA) construct capable of biomimetic responses to vasoactive agents. The project...

Summary The University of Washington Department of Urology received a $106,395 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 1, 2025, through August 31, 2030. This Mentored Urology Research Experience program delivers comprehensive research education and career development services designed to train medical students and...

This federal Project Grant award of $1,136,506.00 from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program supports research by Vanderbilt University Medical Center (VUMC) on INTEGRIN BETA1, a mediator of clear cell renal cell carcinoma metastasis and growth. The award commenced on Sep 1, 2024 and is scheduled for completion by Aug 31, 2028. VUMC, a prominent academic medical center and nonprofit healthcare provider, will conduct this specialized...

Summary Vanderbilt University received a $336,748 Cooperative Agreement award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), effective September 2, 2025, through August 31, 2027. The award funds development and testing of a caregiver-implemented early intervention model for toddlers with nonsyndromic cleft lip and/or palate (NSCL/P). The project will develop bilingual (English and Spanish) coaching...

Project Grant Summary: Energy Balance and Reproductive Health After Early-Onset Colorectal Cancer The National Cancer Institute (NCI) awarded Vanderbilt University Medical Center a $518,470 Project Grant, effective June 1, 2026, through May 31, 2031, under the Cancer Cause and Prevention Research program (CFDA 93.393). This research initiative addresses reproductive health outcomes in young colorectal cancer (CRC) patients by examining the relationship between physical activity, energy...