Project Grant R01CA308492
- Federal Grant Award Summary Vanderbilt University Medical Center received a $4.17 million Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) awarded September 10, 2025, with completion targeted for August 31, 2029. The award funds a comprehensive genomic research initiative titled "Leveraging Omics and Electronic Health Records Data to Study Colorectal Adenoma Genetics and Drug Repurposing." The project addresses the...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc., a Project Grant of $734,942 under the Cancer Cause and Prevention Research program (CFDA 93.393) effective August 1, 2025, through July 31, 2030. This project addresses cardiovascular disease (CVD) risk in breast cancer survivors by generating novel DNA methylation biomarker data from the Pathways Study, a prospective cohort of 4,504 women diagnosed with...
- The National Cancer Institute awarded a $165,080 Project Grant to the Regents of the University of Michigan (awarded February 4, 2026, with completion by August 31, 2027) under the Cancer Research Manpower program (CFDA 93.398). This project examines guideline-concordant surveillance patterns among young colorectal cancer (CRC) survivors, addressing a documented gap in understanding the distinct survivorship needs and care requirements of this population compared to older CRC patients. The...
- This $189,163 federal Project Grant award from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) aims to investigate the impact of dietary patterns and physical activity on survival outcomes for patients with renal cell carcinoma (RCC). The research team at Brigham & Women's Hospital, with the University of California, San Francisco as a sub-grantee, will leverage data from three large, prospective cohorts to comprehensively evaluate pre-...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $413,971 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) on June 23, 2025, with completion scheduled for May 31, 2027. The grant supports the development and pilot testing of a novel nurse navigator-delivered intervention designed to improve outcomes for women experiencing premature or early menopause following cancer...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded UCSF a $724,840 Project Grant effective August 21, 2025, through July 31, 2030, under the Cancer Cause and Prevention Research program (CFDA 93.393) to investigate the relationship between persistent poverty and colorectal cancer risk through biological, behavioral, and place-based mechanisms. The research leverages existing data from two large population-based cohorts—the Multiethnic Cohort Study (MEC) and...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The MGH Institute of Health Professions, Inc. a Project Grant of $696,498 under the Cancer Cause and Prevention Research program (CFDA 93.393) to develop and optimize a multicomponent intervention designed to improve functional recovery and participation in life activities among breast cancer survivors. The research, spanning from May 1, 2026, through April 30, 2031, will systematically develop an evidence-based intervention...
- The National Cancer Institute (NCI) awarded a $621,406 Project Grant on August 1, 2025, under the 21st Century Cures Act - Beau Biden Cancer Moonshot program (CFDA 93.353) to Fred Hutchinson Cancer Center to evaluate a multilevel intervention designed to improve follow-up colonoscopy completion rates among patients with abnormal Fecal Immunochemical Tests (FIT) in safety-net healthcare settings. The PROACT (Promoting Follow-up of Abnormal Colorectal Cancer Screening Tests through Multilevel...
- The National Cancer Institute (NCI) awarded a $414,446 Project Grant to Colorado State University (CSU) under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to conduct a 12-week group-based videoconference intervention aimed at increasing moderate to vigorous physical activity (MVPA) among cancer survivors. The goal is to examine the efficacy of this virtual exercise intervention in improving physical function, quality of life, and other health outcomes for this population....
- Federal Grant Award Summary The Medical University of South Carolina received a $388,256 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393), effective September 1, 2025 through August 31, 2027. This award supports research investigating the biologic rationale for fallopian tube removal as a preventive intervention against uterine serous carcinoma (USC), a highly aggressive form of uterine cancer responsible for 40% of endometrial...
Project Grant Summary: Energy Balance and Reproductive Health After Early-Onset Colorectal Cancer The National Cancer Institute (NCI) awarded Vanderbilt University Medical Center a $518,470 Project Grant, effective June 1, 2026, through May 31, 2031, under the Cancer Cause and Prevention Research program (CFDA 93.393). This research initiative addresses reproductive health outcomes in young colorectal cancer (CRC) patients by examining the relationship between physical activity, energy balance, and fertility. The project will utilize the Preserving Fertility After Colorectal Cancer (PREFACE) study cohort, actively enrolling 220 patients aged 18-49 years newly diagnosed with CRC at Vanderbilt-Ingram Cancer Center in Nashville, Tennessee. The grant funds prospective data collection and analysis designed to characterize how modifiable behavioral factors—particularly physical activity and sedentary behavior—influence fertility outcomes across the cancer care continuum (diagnosis, treatment, and surveillance phases). The research deliverables include validated questionnaires assessing physical activity and reproductive health, accelerometry-based physical activity measurements, and analysis of fasting blood samples collected at uniform study timepoints. These data will establish whether and how patterns of physical activity frequency, duration, intensity, and type change over the cancer treatment trajectory and will identify fertility-related concerns specific to reproductive-age CRC patients, ultimately generating evidence to inform clinical care management and surveillance protocols for young cancer survivors.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $518.5k | 5/14/26 |