Cooperative Agreement H75DP002725

This $624,583 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research at the University of Washington to identify potential therapeutic targets for preventing ischemic stroke. The project will leverage existing plasma samples, genomic data, and electronic medical records from the Heart and Vascular Health Study to evaluate...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, provides $835,288 to Pennsylvania State University's Milton S. Hershey Medical Center to conduct research on the mechanisms of cognitive impairment caused by atherosclerosis and red blood cell-released ATP. The research aims to identify how atherosclerotic blockage of...

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a 2-year, $423,500 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to Wayne State University in Detroit, MI. The objective of this high-risk, high-reward research project is to investigate the use of remotely administered hypothermia (RAH) to the spleen as a novel neuroprotective therapy for ischemic stroke. The research aims to determine if suppressing splenic...

This $834,094 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to advance research on post-stroke cognitive impairment and dementia (PSCID). The funding will support a multi-year effort leveraging a national stroke registry and Medicare data to determine the incidence and prevalence of PSCID, identify associated risk factors, and explore potential pharmacological prevention strategies. Key aspects of the research include a patient-centered approach,...

The National Institute on Aging, part of the Department of Health and Human Services' National Institutes of Health, awarded $3,387,438 under the Aging Research program (CFDA 93.866) to The Ohio State University Office of Sponsored Programs on September 19, 2022. The three-year project grant aims to develop and test a novel neuroprotective agent, TAT-M2NX, to provide both acute and sustained synaptic protection following acute ischemic stroke. The research seeks to characterize the agent's...

The federal Cooperative Agreement award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to conduct a Phase 2A clinical trial to evaluate the safety and efficacy of high-definition cathodal transcranial direct current stimulation (HD C-TDCS) as a neuroprotective and collateral-enhancing treatment for acute ischemic stroke. The $800,331 award, with a...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $481,617.00 in funding to Louisiana State University Health Sciences Center New Orleans to conduct research on neuroprotective lipid mediators and their potential to protect the penumbra region in experimental ischemic stroke. The key objectives are to: 1) test the hypothesis...

This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $457,935 to study the effects of combining continuous theta burst stimulation (a type of transcranial magnetic stimulation) with a modified form of constraint-induced language therapy to treat mild post-stroke aphasia. The primary recipient, The Trustees of the University of...

This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $779,952 to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, for a research project titled "Platelets as Regulator of Non-Neurological Complications of Ischemic Stroke". The project aims to elucidate the role of activated platelets in remote organ injury and infection following ischemic stroke/reperfusion, determine...

This federal Project Grant award for $853,135 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will fund research at Dignity Health's St. Joseph's Hospital and Medical Center in Phoenix, AZ to study the role of the complement C3A receptor in exacerbating brain injury and functional impairment following ischemic stroke. The research aims to...