Cooperative Agreement 2537843
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Macula Vision Systems Inc., a for-profit organization, supports the development of a novel microscopy platform to automate the interpretation of microbiology lab tests performed in hospitals. The project aims to address the shortage of trained lab technicians by engineering a specialized light source, customized camera, and AI-enabled algorithms to analyze...
- The National Science Foundation awarded Lightfinder Inc. $1,247,250 in a Cooperative Agreement on August 1, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop chip-scale optical coherence tomography (OCT) imaging technology for pathology applications. The Phase II Small Business Innovation Research project integrates photonic interferometry, beam steering, and detection into a single silicon chip using scalable CMOS-compatible manufacturing methods. The...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Small Business Innovation Research (SBIR) Phase I project award of $274,998 to Magnify Biosciences Inc. aims to develop an automated "AutoMagnify" device that physically expands biological specimens up to 1,000 times in 3D while preserving spatial and molecular integrity. This advancement will enable conventional light microscopes to achieve nanoscale imaging resolution capabilities...
- This $255,991 National Science Foundation project grant supports the development of an automated system for rapid analysis of biopsy samples by Amcyt, Inc. The system aims to increase the efficiency and accessibility of fine needle aspiration biopsy procedures through three automated processes: sample smearing, staining, and image capture. This addresses a critical need to improve biopsy analytics and potentially eliminate up to 20% of failed procedures due to sampling errors. By automating...
- This $399,935 National Science Foundation (NSF) Project Grant Award under the Computer and Information Science and Engineering program (CFDA 47.070) aims to develop a portable and cost-effective biomedical diagnostic system in the form of an integrated lab-on-a-chip platform produced using additive manufacturing techniques. The key products and services to be delivered include: Advancing 3D manufacturing techniques, particularly in electrode printing, to enhance fabrication precision and...
- Applied Imaging Solutions LLC received a $400,000 Cooperative Agreement from the National Institute of Standards and Technology (NIST) under the Science, Technology, Business and/or Education Outreach program (CFDA 11.620), awarded October 1, 2025, with a completion date of September 30, 2027. The awardee will develop an interpretable artificial intelligence (AI) and deep learning system integrated with a hyperspectral imaging platform designed to conduct label-free, contactless analysis of cell...
- The National Science Foundation (NSF) awarded a $305,000 SBIR Phase I Project Grant to Giant Biosystems Inc. on March 1, 2025. The project aims to develop a rapid, point-of-care antimicrobial susceptibility testing (AST) kit that can provide results on the same day a sample is taken. This is expected to help physicians utilize the most effective antibiotics sooner, reducing antimicrobial resistance and associated economic burdens. The proposed microfluidic platform is designed to generate...
- The National Science Foundation awarded $305,000 to Myxtek Bio, LLC on October 1, 2026 under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) for a Small Business Technology Transfer Phase I project to validate a scalable laboratory model of Bruch's membrane using engineered self-assembling structural proteins. The project addresses the lack of consistent, physiologically accurate laboratory models of Bruch's membrane, a thin eye structure central to age-related macular...
- This National Science Foundation (NSF) Project Grant award under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $305,000 in funding to Nanores LLC for the development of a compact, multi-color super-resolution imaging system capable of visualizing molecular structures in thick biological tissues at nanoscale resolution and depths up to 250 micrometers. The project aims to advance fluorescence imaging capabilities to enable breakthroughs in drug discovery, disease...
- The National Science Foundation awarded a $275,000 Project Grant to Oraliva, Inc. under the Technology, Innovation, and Partnerships program to develop a portable, programmable single cell cytology platform for the early detection of epithelial cancers. The platform will combine microfluidics and artificial intelligence to classify potentially cancerous tissue in near real-time through multiparameter single-cell analysis and automated evaluation. The objectives are to link different clinical...
The National Science Foundation awarded Macula Vision Systems Inc. a $1.249 million cooperative agreement on August 1, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop and validate an automated gram stain interpretation platform using digital holographic microscopy and artificial intelligence. The project will build on Phase I proof-of-concept results to create a compact, cost-effective imaging system capable of high-throughput, full-slide scanning across clinical specimens. Development activities include expanding the system's ability to analyze various sample types, enhancing interpretation algorithms to recognize additional pathogens and host cell features, and implementing a 36-slide batch processing module for increased throughput. Validation studies will benchmark the system against expert microbiologists using deidentified slides, targeting high concordance across multiple laboratories. Upon successful completion, the system will be positioned for commercial launch as a laboratory-developed test to automate the labor-intensive gram stain test, reduce diagnostic errors, and shorten time to appropriate therapy. Performance will occur in Oro Valley, Arizona, with work concluding July 31, 2028. No subawards are planned.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 7/24/26 |