This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) project grant award of $274,998 to Magnify Biosciences Inc. aims to develop an automated device that physically expands biological specimens up to 1000x in 3D, enabling conventional light microscopes to achieve nanoscale imaging resolution typically reserved for costly super-resolution and electron microscopes. The project builds upon expansion microscopy techniques to create rapid protocols and durable gel compositions that address technical challenges, reducing sample preparation time from over a week to less than 24 hours. The expected outcome is a prototype that standardizes sample preparation and staining, making advanced nanoscale imaging more accessible and expanding research capabilities for academic and pharmaceutical labs using conventional microscopes. This innovation has the potential to revolutionize the high-end microscopy market and significantly reduce healthcare costs by enabling pioneering discoveries, innovative diagnostics, and prognostic tools.
Generated 3/4/25, 8:37 AM