Environmental influences on Child Health Outcomes (ECHO) Program
Active
- Assistance listing
- 93.ECH
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Grant awards
- Not on record
Program facts
- Treasury account
-
- 75-0846-0-1-552
- More information
Program details come from SAM.gov Assistance Listings. Updated .
About this program
The National Institutes of Health (NIH) supports the Environmental influences on Child Health Outcomes (ECHO) Program (CFDA 93.ECH) to fund observational and intervention research investigating early environmental influences on childhood chronic disease risk and prevention, with administrative supplement applications currently accepted through November 30, 2028.
The ECHO Program investigates how a broad range of early environmental exposures affect child health and development, distinguishing itself by enabling both observational research and intervention testing within the same cohort structure. Recent grant opportunities reflect the program's maturity: the most recently posted solicitation (PA-26-001, posted August 27, 2025) targets administrative supplements to existing ECHO-funded grants, meaning it serves current recipients seeking additional funding for unforeseen cost increases within the scope of peer-reviewed projects. The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) recently joined as a participating component.
Eligible applicants include domestic public and private nonprofit organizations, universities, colleges, hospitals, laboratories, state and local units of government, for-profit entities, and individuals. The source does not provide a portfolio block with recent award volume, concentration by funding agency, typical award magnitudes, or specific examples of funded projects. Similarly, the source does not describe a primary funding agency, award trends, or the assistance-type mix beyond the general framework that grants are issued.
The administrative supplement pathway documented here requires applicants to hold an active parent award and to secure prior approval from the relevant NIH Institute or Center grants management officer—there is no guarantee of supplement funding availability. The source emphasizes that proposed supplemental research must remain within the original peer-reviewed scope, and as of May 1, 2025, foreign subawards and subcontracts are prohibited unless the parent solicitation explicitly permits international collaborations.
Objective and description
- Objective
The Environmental influences on Child Health Outcomes (ECHO) Program, a nationwide research initiative, aims to investigate the root causes of childhood chronic diseases and how to prevent them. The mission is to enhance the health of children for ge
- Description
The Environmental influences on Child Health Outcomes (ECHO) Program is a research program supported by the National Institutes of Health (NIH), to enhance the health of children for generations to come. The goal of the ECHO Program is to understand the effects of a broad range of early environmental influences on child health and development. ECHO is dedicated to both learning what factors affect child health and to finding ways to enhance it. Part of what makes ECHO unique is that its structure enables investigators to conduct both observational and intervention research. These two types of research within the ECHO Program allow researchers the chance to learn through observation and through testing changes that may enhance child health.
Eligibility
- Applicant eligibility
Awards can be made to domestic, public or private, for-profit or nonprofit organization, university, college, hospital, laboratory, or other institution, including State and local units of government, and individuals. Additional details on eligibility are specified in each Funding Opportunity Announcement.
- Beneficiary eligibility
Private nonprofit institution/organization, Scientist/Researchers, State, Local, Public nonprofit institution/organization, Other public institution/organization
- Uses of assistance
To support research and other projects that will accelerate fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments.
- Use restrictions
The funding may be used to support research activities as described in the funding announcement.
How to apply
- Criteria for selecting proposals
Funding decisions are based on scientific merit (42 CFR 52h) and program relevance. Scientific merit review encompasses: the peer review criteria detailed in the specific funding announcement, as well as the significance, approach, and innovation of the proposed research; the competency of the principal investigator; the adequacy of the resources and environment; the proposed budget and requested period of support; and, where applicable, the adequacy of the measures for protecting against adverse effects upon humans, animals, or the environment.
- Award procedure
Applications are reviewed for scientific and technical merit by a scientific review group and for program relevance by a national advisory council/board.
- Renewals
Renewal applications are accepted, as described in the relevant Funding Opportunity Announcement (FOA) found at: https://grants.nih.gov/funding/explore-nih-opportunities
- Appeals
Not Applicable. A principal investigator may question the substantive or procedural aspects of the review of his/her application by communicating with the NIH Scientific/Research contact, as provided on an initiative. A description of the NIH Peer Review Appeal procedures is available on the NIH Web site at http://grants.nih.gov/grants/guide/notice-files/not97-232.html .
Grant opportunities
| Opportunity | Status | Posted | Applications due |
|---|---|---|---|
| Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) | Open |
Quick answers
What is Assistance Listing 93.ECH?
Assistance Listing 93.ECH is Environmental influences on Child Health Outcomes (ECHO) Program, a federal grant program run by National Institutes of Health (Department of Health and Human Services).
What is the CFDA number for Environmental influences on Child Health Outcomes (ECHO) Program?
Its CFDA number is 93.ECH: Assistance Listing numbers were called CFDA numbers before 2018.
Are there open grant opportunities under 93.ECH?
1 listed opportunity under 93.ECH is open or forecasted. The latest, Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional), was posted on August 27, 2025.
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