High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)

Open Posted

Opportunity number
RFA-DA-25-024
Agency
Applications due
Award size
Not on record

Opportunity facts

Assistance listings
Funding instrument
Grant
Categories
  • Education
  • Health
Eligible applicants
  • Higher Education Inst. (Public)
  • Independent School Districts
  • Small Businesses
  • 501(c)(3) Nonprofits
  • For Profit Organizations
  • Special District Governments
  • County Governments
  • Tribal Governments (Federally Recognized)
  • Higher Education Inst. (Private)
  • State Governments
  • Tribal Organizations (Not Federally Recognized)
  • Non-501(c)(3) Nonprofits
  • Other
  • Public or Indian Housing Auth.
  • City/Township Governments
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institutes of Health is soliciting applications for High Priority HIV and Substance Use Research (R01 Clinical Trial Optional) grants, with applications due March 6, 2027. The program funds research at the intersection of HIV and substance use across all phases from basic science to clinical and implementation research, open to individual researchers and research teams.

Eligible applicants include higher education institutions (public and private), 501(c)(3) nonprofits, for-profit organizations, small businesses, state and local governments, tribal governments (federally and non-federally recognized), tribal organizations, special district governments, public or Indian housing authorities, independent school districts, non-501(c)(3) nonprofits, and other eligible entities. The program also accepts applications from historically Black colleges and universities, Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, Asian American and Native American Pacific Islander serving institutions, tribally controlled colleges and universities, faith-based and community-based organizations, regional organizations, non-domestic entities, and U.S. territories or possessions.

All applications require a detailed research plan, preliminary data, and clear description of nexus with substance use. Studies must align with NIH HIV/AIDS Research Priorities as defined in NOT-OD-20-018. The funding instrument is a grant under the Drug Use and Addiction Research Programs (CFDA 93.279). Support is recommended for project periods not exceeding five years. Recent R01 and cooperative agreement awards within the program range from $300,000 to $865,000. The application deadline was updated to align with NOT-OD-26-029. Applicants must follow the FORMS-I application system, including both general and research-specific instructions as detailed in the Application Guide (PKG00288355.pdf).

Synopsis

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Files

File Type Posted
RFA-DA-25-024-Full-Announcement.html HTML file
PKG00288355.pdf PDF

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