DoW Breast Cancer, Breakthrough Award Level 3
Closed Posted
- Opportunity number
- HT942526BCRPBTA3
- Agency
-
Medical Command
Department of the Army, Department of Defense
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Science and Technology and other Research and Development
- Eligible applicants
-
- Unrestricted
- Points of contact
-
- eBRAP Help Desk help@ebrap.org (301) 682-5507
Opportunity details come from Grants.gov. Updated .
About this opportunity
The Department of the Army Medical Command, through the Congressionally Directed Medical Research Programs (CDMRP), is soliciting applications for the Breast Cancer Research Program Breakthrough Award Level 3, with a pre-application deadline of June 12, 2026 and full application deadline of September 30, 2026. The CDMRP expects to fund approximately two applications with total cost caps of $5.6 million for single PI applications or $7.0 million for Partnering PI Option applications, allocating roughly $12.6 million total. Applicant types are unrestricted; eligible entities include extramural and intramural U.S. Department of War organizations, foreign and domestic organizations, and for-profit and nonprofit entities. Independent investigators may serve as PI regardless of citizenship status.
All applications must address at least one of nine FY26 BCRP overarching challenges including primary prevention, distinguishing deadly from non-deadly cancers, eliminating metastatic breast cancer mortality, and revolutionizing treatment regimens. Research teams must include two or more breast cancer consumer advocates as integral members. Small-scale clinical trials are permitted but not required. The funding mechanism allows for a single Principal Investigator or two partnering PIs; for the Partnering PI Option, only the Initiating PI submits the pre-application, but both PIs must submit at the full application stage.
The maximum period of performance is four years. The two-tier review process evaluates technical merit in peer review and programmatic relevance in program review. Peer review criteria emphasize impact on overarching challenges, research strategy feasibility, personnel qualifications, consumer advocate integration, post-award transition planning, and statistical rigor. Awards are anticipated by September 30, 2027. The funding opportunity number is HT942526BCRPBTA3, assigned under CFDA 12.420 (Military Medical Research and Development).
Synopsis
Summary: The fiscal year 2026 (FY26) Breast Cancer Research Program (BCRP) Breakthrough Award mechanism supports promising research with high potential to lead to or make breakthroughs in breast cancer. All applications must address at least one of the FY26 BCRP overarching challenges or provide adequate justification for exception. Applications must address the challenge in a way that can lead to a breakthrough and have major impact. The FY26 Breakthrough Award mechanism contains four different funding levels designed to support major (but not all) stages of research that will lead to clinical application. Each level specifies a distinct research scope. This program announcement discusses the Breakthrough Award Level 3.
Distinctive Features:
· For this funding mechanism, small-scale clinical trials are allowed but not required. Applications proposing projects with a clinical trial should be submitted under the Clinical Trial option.
· The research team must include two or more breast cancer consumer advocates.
· This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. For the Partnering PI Option (PPIO), only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. Be advised, failure to submit all associated (Initiating and Partnering PI) applications by the deadline may result in administrative withdrawal.
Files
| File | Type | Posted |
|---|---|---|
| PKG00292635.pdf | ||
| HT942526BCRPBTA3_GG.pdf | ||
| HT942526BCRPBTA3_GG.pdf | ||
| HT942526BCRPBTA3_GG.pdf |
On GovTribe
Work this opportunity
- Track it in your pipeline
- Find teaming partners
- Similar grant opportunities
- Ask GovTribe AI about this opportunity