Chain Reaction Innovations - Energy Technology Innovation

The Department of Energy Office of Science is seeking innovative entrepreneurs for the Chain Reaction Innovations (CRI) program's 2026 cohort, focusing on physical sciences and energy technologies research and development. Selected innovators will receive up to 24 months of comprehensive support including personal stipends, health benefits, laboratory space, technical collaboration, and entrepreneurial mentorship through Argonne National Laboratory. Key eligibility requirements include technical leads having at least 5 years of R&D experience, U.S. citizenship or permanent residency status, and having raised no more than $2 million in private equity funding. The selection process evaluates candidates based on the project leader's capabilities, the technical and economic potential of their project concept, and alignment with DOE's technology mission areas. Applications must be submitted through chainreaction.anl.gov and include comprehensive documentation covering background information, technology vision, business concepts, and technical presentations, with a submission deadline of November 7, 2025.

This solicitation does not utilize any set-aside designations and will operate under Cooperative Research and Development Agreement (CRADA) structures with selected participants. The program involves two distinct phases: a Scope and Planning Phase followed by an R&D Phase, providing structured progression for accepted innovators. While specific award values are not disclosed in the solicitation notice, the program offers substantial in-kind support through laboratory access, mentorship, and benefits packages rather than traditional monetary contracts. The place of performance is designated as Lemont, Illinois 60439, where participants will have access to Argonne National Laboratory facilities and resources. The solicitation falls under NAICS code 54171 for Research and Development in Physical, Engineering, and Life Sciences, reflecting the program's focus on advancing energy technology innovations through individual entrepreneur development.