36C24E22Q0197 0001.docx

Solicitation 36C24E22Q0197

5. PROJECT NUMBER (if applicable)

CODE

7.

ADMINISTERED BY

2. AMENDMENT/MODIFICATION NUMBER

CODE

6. ISSUED BY

8. NAME AND ADDRESS OF CONTRACTOR

4. REQUISITION/PURCHASE REQ. NUMBER

3. EFFECTIVE DATE

9A. AMENDMENT OF SOLICITATION NUMBER

9B. DATED

PAGE OF

PAGES

10A. MODIFICATION OF CONTRACT/ORDER NUMBER

10B. DATED

BPA NO.

1. CONTRACT ID CODE

FACILITY CODE

CODE

Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:

The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers

E. IMPORTANT:

is extended,

(a) By completing Items 8 and 15, and returning __________ copies of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted; or (c) By separate letter or electronic communication which includes a reference to the solicitation and amendment numbers. FAILURE

OF YOUR

ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY is not extended.

12. ACCOUNTING AND APPROPRIATION DATA

(REV. 11/2016)

is required to sign this document and return ___________ copies to the issuing office.

is not, A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A.

15C. DATE SIGNED

B. THE ABOVE NUMBERE

D CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES

SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b).

RESULT IN REJECTION OF YOUR

OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by letter or electronic communication, provided each letter or electronic communication makes reference to the solicitation and this amendmen t, and is received prior to the opening hour and date specified.

C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

D. OTHER

Contractor

16C. DATE SIGNED

14. DESCRIPTION OF AMENDMENT/MODIFICATION

16B. UNITED

STATES OF AMERICA

Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.

15A. NAME AND TITLE OF SIGNER

16A. NAME AND TITLE OF

CONTRACTING OFFICER

15B. CONTRACTOR/OFFEROR

STANDARD FORM 30

PREVIOUS EDITION NOT USABLE

Prescribed by GSA - FAR (48 CFR) 53.243 (Type or print) (Type or print) (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)

(Number, street, county, State and ZIP Code) (If other than Item 6) (Specify type of modification and authority) (such as changes in paying office, appropriation date, etc.)

(If required)

(SEE ITEM 11)

(SEE ITEM 13)

(X)

CHECK

ONE

13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS,

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF

SOLICITATIONS

AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT

(Signature of person authorized to sign) (Signature of Contracting Officer) 09/12/2022 None 00240E US Department of Veterans Affairs Veterans Health Administration Regional Procurement Office (RPO) East 323 North Shore Drive, Suite 500 Pittsburgh PA 15212-5319 00240E US Department of Veterans Affairs Veterans Health Administration Regional Procurement Office (RPO) East 323 North Shore Drive, Suite 500 Pittsburgh PA 15212-5319 To all Offerors/Bidders

36C24E22Q0197 08-30-2022

X X X

09/23/2022, 11AM EST

X The purpose of this amendment is to extend the due date and answer all questions.

The due date is hereby extended from 09/13/2022, 3PM EST through 09/23/2022, 11AM EST.

Please see p.2 for questions and answers.

Sign and return this amendment with quotes by 09/23/2022, 11AM EST. Respond by email only to Ann Marie Stewart, at annmarie.stewart@va.gov.

Ann Marie Stewart Contracting Officer

VA-VHA-2021-9A527CD0

Questions and answers

1. Can one company submit two quotes for different products? Are we talking about 2 different cryogen-free 9.4T PET/MRI system?

2. Will you require a reference list of existing fully functioning sites using the vendors solutions for 9.4 PET/MR? We definitely would like to see a reference list of installed (or being installed) cryogen-free 9.4T MRI with PET capabilities.

3. Which application areas will require simultaneous PET/MR? Metabolic/molecular/structural imaging applications.

4. What application requires that traumatic brain studies on mice and rats accommodate animals up to 2.5kg for MRI-only applications? To accommodate larger animal models such as rabbits.

5. Are there whole body rat applications or is the rat research related primarily to brain research? There are rat brain research as well as whole body research including cardiovascular and abdominal imaging research.

6. What animal models do you wish to image? Mice, rats, rabbit.

7. Does you research require dedicated and optimized PET/MR Brain coils for rat and mice that have highest SNR in the brain, minimized attenuation effects for PET and allows for the measurement of the MR based attenuation map in a single bed position? Yes

8. Does the 600 mT/m gradient need to be available for use in simultaneous PET/MR with no exchange of the main system gradient? Yes.

9. Since we do not believe that a 120mm ID RF coil can accommodate a 2.5kg. animal should the system requirement include a 140mm ID RF coil? Venders can provide options that meet or exceed the stated system specifications.

10. Would much higher slew rates of up to 4200 mT/m/s in combination with short ramp times of 150us and strong gradient strength up to 900 mT/m of a mouse & rat brain PET/MR scanner beneficial to achieve better high quality PET/MR imaging results at high fields? Yes, higher performance main gradient systems should be beneficial for better imaging outcome which would have to be demonstrated during acceptance testing.

11. Would stronger second order shims of up to 3750 Hz/cm2 in combination with 240 Hz/cm3 Z3 shims of a mouse & rat brain PET/MR scanner be an improvement for high quality high-field fMRI and spectroscopy PET/MR? Stronger second order shims could improve the quality of fMRI and spectroscopy – again this would need verification demonstrated during acceptance testing.

12. Can you please be more precise and clear in the required electronic channel configuration and define more specifically what linear or low noise means? The system must be equipped with two (2) RF transmit channels and eight (8) receive channels. Linearity and noise amplitude will be a function of vendor provided components. The combination of all system components meeting specifications will determine the final system chosen.

13. Regarding Low noise narrowband preamplifier please specify how many and which band. We are seeking a system with a minimum of 8 preamplifiers –providing operational capabilities at narrowband for 1H and also at broadband frequencies for multi-nuclei.

14. Regarding the minimum of 2 Linear Pre-amplifiers please clarify why 2 when there are 4 receive channels There are a total of 8 receive channels and 8 pre-amplifiers required.

15. Minimum of 2 preamplifiers specifically optimized for MRI spectroscopy applications for any of the following nuclei: 31P, 22Na, 13C, 19F, 3He, 17O or 129Xe please clarify why 2 broadband preamplifiers when only 1 X-nuclei is detected We are requesting the system include a minimum of 2 broadband pre-amplifiers for current applications.

16. Do you require a single nucleus X-transmit only coil, or rather a 1H/X coil with active detuning for the X nuclei to allow the use of X-nuclei receive-only coils? We recommend the vendor provide both options with VA choosing optimal configuration.