08_-_EXHIBIT_C_-_Uniform_Classification_Guidelines.pdf

Version 16.0, April 2023

Ve

DRUG TESTING STANDARDS AND

PRACTICES PROGRAM.

Uniform Classification Guidelines for Foreign Substances And Recommended Penalties Model Rule.

April, 2023 (V.16.0)

© ASSOCIATION OF RACING COMMISSIONERS INTERNATIONAL – 2023.

Association of Racing Commissioners International

2365 Harrodsburg Road, Suite B-450, Lexington, Kentucky USA 40504 www.arci.com

Preamble to the Uniform Classification Guidelines of Foreign Substances

EXHIBIT C

http://www.arci.com/

The Preamble to the Uniform Classification Guidelines was approved by the RCI Drug Testing and Quality Assurance Program Committee (now the Drug Testing

Standards and Practices Program Committee) on August 26, 1991. Minor revisions to the Preamble were made by the Drug Classification subcommittee (now the

Veterinary Pharmacologists Subcommittee) on September 3, 1991.

"The Uniform Classification Guidelines printed on the following pages are intended to assist stewards, hearing officers and racing commissioners in evaluating the seriousness of alleged violations of medication and prohibited substance rules in racing jurisdictions. Practicing equine veterinarians, state veterinarians, and equine pharmacologists are available and should be consulted to explain the pharmacological effects of the drugs listed in each class prior to any decisions with respect to penalities to be imposed. The ranking of drugs is based on their pharmacology, their ability to influence the outcome of a race, whether or not they have legitimate therapeutic uses in the racing horse, or other evidence that they may be used improperly. These classes of drugs are intended only as guidelines and should be employed only to assist persons adjudicating facts and opinions in understanding the seriousness of the alleged offenses. The facts of each case are always different and there may be mitigating circumstances which should always be considered. These drug classifications will be reviewed frequently and new drugs will be added when appropriate."

Notes Regarding Classification Guidelines

• Where the use of a drug is specifically permitted by a jurisdiction, then the jurisdiction’s rule supersedes these penalty guidelines.

• Regulators should be aware that a laboratory report may identify a drug only by the name of its metabolite. The metabolite might not be listed here, but the parent compound may be.

• These classes of drugs are intended only as guidelines and should be employed only to assist persons adjudicating facts and opinions in understanding the seriousness of the alleged offenses.

• The facts of each case are different and there may be mitigating circumstances that should be considered.

• These drug classifications will be reviewed periodically. New drugs will be added or some drugs may be reclassified when appropriate.

• Racing Commissioners International (RCI) and/or the Racing Medication and Testing Consortium (RMTC) should be consulted for found substances or drugs not included in these guidelines and treated as Class 1 violations warranting a Class A penalty unless otherwise advised.

Classification Criteria

The RCI Drug Classification Scheme is based on 1) pharmacology, 2) drug use patterns, and 3) the appropriateness of a drug for use in the racing horse. Categorization is decided using the following general guidelines:

• Pharmacology. Drugs that are known to be potent stimulants or depressants are placed in higher classes, while those that have (or would be expected to have) little effect on the outcome of a race are placed in lower classes.

• Drug Use Patterns. Some consideration is given to placement of drugs based on practical experience with their use and the nature of positive tests. For example, procaine positives have in the past been associated primarily with the administration of procaine penicillin, and this has been taken into consideration in the placement of procaine into Class 3 instead of Class 2 with other injectable local anesthetics.

• Appropriateness of Drug Use. Drugs that clearly are intended for use in equine therapeutics are placed in lower classes. Drugs that clearly are not intended for use in the horse are placed in higher classes, particularly if they might affect the outcome of a race. Drugs that are recognized as legitimately useful in equine therapeutics but could affect the outcome of a race are placed in the middle or higher classes.

The list includes most drugs that have been reported as detected by racing authority laboratories in the United States, Canada, the United Kingdom and other

Association of Official Racing Chemists (AORC) laboratories, but does not include those which would seem to have no effect on the performance of the horse or drug detectability. For example, it does not include antibiotics, sulfonamides, vitamins, anthelmintics, or pangamic acid, all of which have been reported.

The list contains many drugs that have never been reported as detected. Usually, these are representatives of chemical classes that have the potential for producing an effect, and in many cases, for which at least one drug in that chemical class has been reported.

Most drugs have numerous effects, and each was judged on an individual basis. There are instances where there is a rather fine distinction between drugs in one category and those in the next. This is a reflection of a nearly continuous spectrum of effects from the most innocuous drug on the list to the drug that is the most offensive.

Classification Definitions

• Class 1: Stimulant and depressant drugs that have the highest potential to affect performance and that have no generally accepted medical use in the racing horse.

Many of these agents are Drug Enforcement Agency (DEA) schedule II substances. These include the following drugs and their metabolites: Opiates, opium derivatives, synthetic opioids and psychoactive drugs, amphetamines and amphetamine-like drugs as well as related drugs, including but not limited to apomorphine, nikethamide, mazindol, pemoline, and pentylenetetrazol. Though not used as therapeutic agents, all DEA Schedule 1 agents are included in Class

1 because they are potent stimulant or depressant substances with psychotropic and often habituative actions. This class also includes all erythropoietin stimulating substances and their analogues.

• Class 2: Drugs that have a high potential to affect performance, but less of a potential than drugs in Class 1. These drugs are 1) not generally accepted as therapeutic agents in racing horses, or 2) they are therapeutic agents that have a high potential for abuse. Drugs in this class include: psychotropic drugs, certain nervous system and cardiovascular system stimulants, depressants, and neuromuscular blocking agents. Injectable local anesthetics are included in this class because of their high potential for abuse as nerve blocking agents.

• Class 3: Drugs that may or may not have generally accepted medical use in the racing horse, but the pharmacology of which suggests less potential to affect performance than drugs in Class 2. Drugs in this class include bronchodilators, anabolic steroids and other drugs with primary effects on the autonomic nervous system, procaine, antihistamines with sedative properties and the high-ceiling diuretics.

• Class 4: This class includes therapeutic medications that would be expected to have less potential to affect performance than those in Class 3. Drugs in this class includes less potent diuretics; corticosteroids; antihistamines and skeletal muscle relaxants without prominent central nervous system (CNS) effects;

expectorants and mucolytics; hemostatics; cardiac glycosides and anti-arrhythmics; topical anesthetics; antidiarrheals and mild analgesics. This class also includes the non-steroidal anti-inflammatory drugs (NSAIDs), at concentrations greater than established limits.

• Class 5: This class includes those therapeutic medications that have very localized actions only, such as anti-ulcer drugs, and certain anti-allergic drugs. The anticoagulant drugs are also included.

• Prohibited Practices:

A) The possession and/or use of a drug, substance or medication, specified below, on the premises of a facility under the jurisdiction of the regulatory body for which a recognized analytical method has not been developed to detect and confirm the administration of such substance; or the use of which may endanger the health and welfare of the horse or endanger the safety of the rider or driver; or the use of which may adversely affect the integrity of racing:

1) Erythropoietin

2) Darbepoetin

3) Oxyglobin

4) Hemopure

B) The possession and/or use of a drug, substance, or medication on the premises of a facility under the jurisdiction of the regulatory body that has not been approved by the United States Food and Drug Administration (FDA) for use in the United States.

C) The practice, administration, or application of a treatment, procedure, therapy or method identified below, which is performed on the premises of a facility under jurisdiction of a regulatory body and which may endanger the health and welfare of the horse or endanger the safety of the rider or driver, or the use of which may adversely affect the integrity of racing:

Drug Classification Scheme

• Class 1: Opiates, opium derivatives, synthetic opioids, psychoactive drugs, amphetamines, and all DEA Schedule I substances (see http://www.deadiversion.usdoj.gov/schedules/#list), and many DEA Schedule II drugs. Also found in this class are drugs that are potent stimulants of the CNS.

Drugs in this class have no generally accepted medical use in the racing horse and their pharmacologic potential for altering the performance of a racing horse is very high. This class also includes all erythropoietin stimulating substances and their analogues.

• Class 2: Drugs placed in this category have a high potential for affecting the outcome of a race. Most are not generally accepted as therapeutic agents in the racing horse. Many are products intended to alter consciousness or the psychic state of humans, and have no approved or indicated use in the horse. Some, such as injectable local anesthetics, have legitimate use in equine medicine, but should not be found in a racing horse. The following groups of drugs are placed in this class:

A) Opiate partial agonists, or agonist-antagonists.

B) Non-opiate psychotropic drugs. These drugs may have stimulant, depressant, analgesic or neuroleptic effects.

C) Miscellaneous drugs, which might have a stimulant effect on the CNS.

D) Drugs with prominent CNS depressant action.

E) Anti-depressant and antipsychotic drugs, with or without prominent CNS stimulatory or depressant effects.

F) Muscle blocking drugs - those that have a direct neuromuscular blocking action.

G) Local anesthetics that have a reasonable potential for use as nerve-blocking agents (except procaine).

H) Snake venoms and other biologic substances that may be used as nerve-blocking agents.

• Class 3: Drugs placed in this class may or may not have an accepted therapeutic use in the horse. Many are drugs that affect the cardiovascular, pulmonary and autonomic nervous systems. They all have the potential of affecting the performance of a racing horse. The following groups of drugs are placed in this class:

A) Drugs affecting the autonomic nervous system that do not have prominent CNS effects, but which do have prominent cardiovascular or respiratory system effects. Bronchodilators are included in this class.

B) A local anesthetic that has nerve-blocking potential but also has a high potential for producing urine residue levels from a method of use not related to the anesthetic effect of the drug (procaine).

C) Miscellaneous drugs with mild sedative action, such as the sleep-inducing antihistamines.

D) Primary vasodilating/hypotensive agents.

E) Potent diuretics affecting renal function and body fluid composition.

F) Anabolic and/or androgenic steroids and other drugs.

• Class 4: Drugs in this category comprise primarily therapeutic medications routinely used in racehorses. These may influence performance, but generally have a more limited ability to do so. Groups of drugs assigned to this category include the following:

http://www.deadiversion.usdoj.gov/schedules/#list) http://www.deadiversion.usdoj.gov/schedules/#list) http://www.deadiversion.usdoj.gov/schedules/#list)

A) Non-opiate drugs that have a mild central antipyretic effect.

B) Drugs affecting the autonomic nervous system that do not have prominent CNS, cardiovascular, or respiratory effects:

1) Drugs used solely as topical vasoconstrictors or decongestants.

2) Drugs used as gastrointestinal antispasmodics.

3) Drugs used to void the urinary bladder.

4) Drugs with a major effect on CNS vasculature or smooth muscle of visceral organs.

C) Antihistamines that do not have a significant CNS depressant effect. This does not include the H2 blocking agents, which are in Class 5.

D) Mineralocorticoid drugs.

E) Skeletal muscle relaxants.

F) Anti-inflammatory drugs. These drugs may reduce pain as a consequence of their anti-inflammatory action.

1) Non-steroidal anti-inflammatory drugs (NSAIDs). (Aspirin-like drugs).

2) Corticosteroids (glucocorticoids).

3) Miscellaneous anti-inflammatory agents. G. Less potent diuretics.

H. Cardiac glycosides and antiarrhythmic agents.

1. Cardiac glycosides.

2. Antiarrhythmic agents (exclusive of lidocaine, bretylium, and propranolol).

3. Miscellaneous cardiotonic drugs.

I. Topical Anesthetics - agents not available in injectable formulations.

J. Antidiarrheal drugs.

K. Miscellaneous drugs:

1. Expectorants with little or no other pharmacologic action.

2. Stomachics.

3. Mucolytic agents.

• Class 5: Drugs in this category are therapeutic medications that have very localized actions only, such as anti-ulcer drugs, and certain antiallergic drugs. The anticoagulant drugs are also included.

Drug/Substance Trade Name(s) Drug Class Penalty Class Special Notation Note.

∆-1-androstene-3, 17diol

A

∆-1-androstene-3, 17dione

3 A

∆-1-dihydrotestosterone

1-androstenediol

(5aandrost-1-ene-3β, 17βdiol)

B

Steroid - endogenous weak androgen steroid hormone and intermediate in the biosynthesis of testosterone from dehydroepiandrosterone

(DHEA) and of estrone.

Endogenous AAS

1-androstenedione

(5aandrost-1-ene-3, 17dione)

Steroid - endogenous weak androgen steroid hormone and intermediate in the biosynthesis of testosterone from

1-testosterone

(17βhydroxy-5a-androst-1en-3-one)

Steroid - chemically related to anabolic steroids.

AAS lacking FDA approval

19-Norandrostenediol

19-Norandrostenedione 3 B

19-noretiocholanolone.

Nandrolene Link - a metabolite of nandrolone

(19-nortestosterone) and bolandione

(19norandrostenedione).

Metabolite of a B substance

2-Aminoheptane Tuamine 4 B

3-Methoxytyramine 3-MT 2 A

3,4-methylenedioxypyprova lerone

MDPV, “bath salts” 1

4-androstene-3,6,17 trione (6-oxo)

Hormone and Metabolic effects, same classification as Testolactone on Human

Olympic Guidelines -

Aromatase inhibitors.

Testolactone has B classification

4-androstenediol

(androst-4-ene-

3β,17βdiol)

Testosterone Link -androstenediol that is converted to testosterone.

Metabolized to a B substance

4-Hydroxytestosterone

5-androstenedione

(androst-5- ene-

3,17dione) prohormone of testosterone.

5α-androstane-

3α,17αdiol

B

Testosterone Link -testosterone metabolite.

Metabolite of a B substance

5α-androstane-

3α,17βdiol

3 B Testosterone Link -testosterone metabolite.

Metabolite of a B substance

5α-androstane-

3β,17αdiol

3 B Testosterone Link -testosterone metabolite.

Metabolite of a B substance

5α-androstane-

3β,17βdiol

3 B Testosterone Link -testosterone metabolite.

Metabolite of a B substance

5β-androstane-3 α, 17βdiol, androst-4-ene3α,17α-diol

7-keto-dhea;19-

DHEA Link - a steroid produced by metabolism of the prohormone

(DHEA).

7α-hydroxy-dhea

DHEA Link - naturally occurring steroid and a major metabolite of

7β-hydroxy-dhea

DHEA Link - naturally occurring steroid and a major metabolite of a-Cobratoxin 1 A

Acebutolol Sectral

Acecarbromal

Acenocoumarol 5 C

Acepromazine Atrovet, Notensil, PromAce®

Acetaminophen

(Paracetamol) Tylenol, Tempra, etc.

4 C

Acetanilid

Acetazolamide Diamox, Vetamox 4 C

Acetophenazine Tindal 2 A

Acetophenetidin

(Phenacetin)

Acetylcysteine

C

Acetylsalicylic acid

(Aspirin)

Activators of the

AMPactivated protein kinase (AMPK) - E.g., AICAR, and Peroxisome

Proliferator Activated

Receptor δ (pparδ) agonists (e.g., GW

1516).

AICAR

effects, same classification as Testolactone on Human

Olympic Guidelines.

PPARs are experimental drugs without FDA approval

Adinazolam

Adrenochrome monosemicarbazone salicylate

Albuterol (Salbutamol) Proventil, Ventolin

B NOTE: "A" penalty for quarter horse races.

Alclofenac 2 B

Alclometasone Aclovate 4 C

Alcuronium Alloferin 2 A

Aldosterone Aldocortin, Electrocortin

Alfentanil Alfenta 1 A

Almotriptan Axert 3 A

Alphaprodine Nisentil

Alpha-pyrrolidinovalerophenone

(also known as Alpha

PVP)

A

Known as bath salts in humans

Alpidem Anaxyl

Alprazolam Xanax

Alprenolol

Althesin Saffan

Altrenogest

Regumate 4 C *Classification for geldings, colts, adult intact males, spayed females only.

Ambenonium Mytelase, Myeuran 3 B

Ambroxol Ambril, etc. 4 B

Amcinonide Cyclocort 4 C

Amiloride Moduretic; Midamor 4 B

Aminocaproic acid Amicar, Caprocid 4 C

Aminoglutethimide effects, same classification as Testolactone on Human

Olympic Guidelines.

Aminophylline Aminophyllin, etc. 3 B

Aminopyrine

Aminorex Aminoxafen, Aminoxaphen, Apiquel, McN-742, Menocil

Amiodarone

Amisometradine Rolictron 4 B

Amisulpride Solian

Amitraz Mitaban 3 B

Amitriptyline Elavil, Amitril, Endep 2 A

Amlodipine Ammivin, Norvasc 3 B

Amobarbital Amytal 2 A

Amoxapine Asendin 2 A

Amperozide

Amphetamine

Amrinone

Amyl nitrite

Anastrozole effects, same classification as Testolactone on Human

Andarine

SARM

Androst-4-ene-

3α,17βdiol

Testosterone Link - an

Androst-4-ene-

3β,17αdiol

Testosterone Link - an

Androst-5-ene-

3α,17αdiol

3α,17βdiol

3β,17αdiol

Androsta-1,4,6-triene-

3,17-dione

(androstatrienedione) effects, same classification as Testolactone on Human

Androstenediol

(androst-5-ene-3β, 17βdiol)

Steroid: weak androgen and estrogen steroid hormone and intermediate in the biosynthesis of testosterone from dehydropiandrosterone

(DHEA)

Androstenedione

(androst-4-ene-3, 17dione)

Steroid: endogenous weak androgen steroid hormone and intermediate in the biosynthesis of testosterone from

Androsterone (3 βhydroxy-5 α – androstan-17-one)

Testosterone Link - a metabolite of testosterone and dihydrotestosterone

(DHT).

Anileridine Leritine

Anilopam Anisine 2 A

Anisindione 5 D

Anisotropine Valpin 4 B

Antipyrine

Apazone

(Azapropazone) Rheumox

Apomorphine

Aprindine

Aprobarbital Alurate

ARA-290

Erythropoietin Link - a nonerythropoietic peptide engineered from erythropoietin.

Blood doping agent

Arecoline

Arformoterol

Aripiprazole Abilify 2 A

Arsenic

Arsenic is present in pressure-treated lumber designated for non-residential use. Cribbing or wood chewing may result in expsoure sufficient to result in concentrations in excess of the screening limit. Findings for arsenic warrant investigation into the route of exposure with mitigation to 3/C recommended when there is compelling evidence for environmental exposure rather than deliberate administration.

Aromatase inhibitors listed:

Articaine Septocaine; Ultracaine, 2 B

Asialo EPO

Erythropoietin Link -desialylated form of human glycoprotein hormone erythropoietin (EPO), which has been reported to be neuro-, cardio-, and renoprotective in animal models of organ injuries.

Atenolol Tenormin

Atipamazole

Atomoxetine Strattera

Atracurium Tracrium

Atropine

Azacylonol Frenque 2 A

Azaperone Stresnil, Suicalm, Fentaz

(with Fentanyl)

Baclofen Lioresal 4 B

Barbital Veronal 2 A

Barbiturates

Beclomethasone Propaderm 4 C

Bemegride Megimide, Mikedimide

Benazepril Lotrel, Lotensin 3 A

Bendroflumethiazide Naturetin 4 B

Benoxaprofen

Benoxinate Dorsacaine

Benperidol

Anquil

Bentazepam

Tiadipona 2 A

Benzactizine Deprol, Bronchodiletten 2 A

Benzocaine

Benzoctamine

Benzodiazepines

Benzonatate Tessalon, Tessalon Perles, Zonatuss

Benzphetamine

Didrex 2 A

Benzthiazide

Benztropine

Cogentin

Benzylpiperazine (BZP)

Bepridil

Bepadin

Betamethasone Betasone, etc. 4 C

Betaxolol

Kerlone

Bethanechol Urecholine, Duvoid

Bethanidine

Esbatal

Biperiden Akineton

Biriperone

Bisoprolol Zebeta, Bisobloc, etc.

Bisphosphonates (any)

Bitolterol

Effectin 3 A

Bolandiol (estr-4-ene3β, 17β-diol)

Steroid

Bolasterone

Boldenone Equipoise

Boldione

Botulinum toxin

Bretylium Bretylol

Brimonidine Alphagan

Bromazepam Lexotan, Lectopam 2 A

Bromfenac Duract

Bromhexine Oletor, etc. 4 B

Bromisovalum Diffucord, etc.

Bromocriptine Parlodel

Bromodiphenhydramin e

Bromperidol Bromidol

Brompheniramine Dimetane, Disomer

Brotizolam Brotocol

Budesonide Pulmacort, Rhinocort

Bufotenine

A

Penalty recommendation for when detected in urine. No threshold has been adopted if found in blood. Further investigation is necessary.

Bufexamac

Bumetanide Bumex

Bupivacaine Marcaine

Buprenorphine Temgesic

Bupropion Wellbutrin 2 A

Buspirone Buspar

Butabarbital

(Secbutobarbitone) Butacaps, Butasol, etc.

Butacaine Butyn

Butalbital (Talbutal) Fiorinal 2 A

Butamben (butyl aminobenzoate) Butesin

Butanilicaine Hostacain 2 A

Butaperazine Repoise

Butoctamide Listomin

Butorphanol Stadol, Torbugesic

Butoxycaine Stadacain

Caffeine

Calusterone Methosorb 3 A

Camazepam Paxor

Camphor

Candesartan Atcand

Cannabidiol (CBD)1 Anti-epileptic, analgesic 2 B

Canrenone

Metabololite of a C substance - steroidal antimineralocorticoid, active metabolite of spironolactone (a diuretic).

Capsaicin

Captodiame Covatine

Captopril Capolen 3 B

Carazolol Carbacel, Conducton

Carbachol Lentin, Doryl 3 B

Carbamezapine Tegretol 3 B

Carbamylated EPO

Erythropoietin Link - may be a beneficial tissueprotective cytokine.

Carbazochrome

Carbidopa + levodopa Sinemet

Carbinoxamine Clistin

Carbromol Mifudorm

Cardarine (GW-501516) 2 A No legit use in the racehorse. Lacks FDA approval

Carfentanil

Carisoprodol Rela, Soma 2 B

Carphenazine Proketazine 2 A

Carpipramine Prazinil 2 A

Carprofen Rimadyl 4 B

Carteolol Cartrol

Carticaine (see articaine) Septocaine; Ultracaine, etc.

Carvedilol Coreg

Cathinone khat, kat, qat, quat, chat, catha, Abyssinian tea, African tea

Celecoxib Celebrex

Cetirizine Zyrtec 4 C

Chloral betaine Beta-Chlor 2 A

Chloral hydrate Nactec, Oridrate, etc. 2 A

Chloraldehyde (chloral)

Chloralose

(AlphaChloralose)

Chlordiazepoxide

Librium 2 A

Chlorhexidol

Chlormerodrin

Neohydrin

Chlormezanone

Trancopal

Chloroform

Chlorophenesin

Maolate 4 C

Chloroprocaine

Nesacaine 2 A

Chloroquine

Avloclor 4 C

Chlorothiazide

Diuril

Chlorpheniramine

Chlortriemton, etc. 4 B

Chlorproethazine

Newiplege

Chlorpromazine

Thorazine, Largactil 1 A

Chlorprothixene

Taractan 2 A

Chlorthalidone

Hydroton 4 B

Chlorzoxazone

Paraflex 4 B

Chorionic

Gonadotropin (CG)

Hormone and behavioral effects - a water soluble glycoprotein derived from human pregnancy urine. Used for behavior modification in colts / horses. There should be no restriction/regulation in fillies and mares.

Ciclesonide

Cilostazol

Pletal

Cimeterol

Cimetidine

Tagamet

Cinchocaine Nupercaine 2 B

Citalopram Celex 2 A

Clanobutin

Clemastine Tavist

Clenbuterol Ventipulmin 3 B NOTE: "A" penalty for quarter horse races.

Clibucaine Batrax 2 A

Clidinium Quarezan, Clindex, etc. 3 B

Clobazam Urbanyl

Clobetasol Temovate 4 C

Clocapramine

Clocortolone Cloderm 4 C

Clodronate OsPhos 3 A Bisphosphonate

Clofenamide

Clomethiazole

(Chlormethiazole)

Clomiphene effects, same classification as Testolactone on Human

Estrogen modulator.

Clomipramine Anafranil

Clonazepam Klonopin 2 A

Clonidine Catapres 3 B

Clorazepate Tranxene 2 A

Clormecaine Placacid 2 A

Clostebol

Clothiapine Entermin 2 A

Clotiazepam Trecalmo, Rize 2 A

Cloxazolam Enadel, Sepazon, Tolestan

Clozapine Clozaril, Leponex

CNTO 530

Erythropoietin Link - a biopharmaceutical consisting of a novel peptide that mimics the actions of erythropoietin, CNTO 530 produced sustained increases in red blood cell parameters.

Cobalt (check note)

B1

For cobalt concentrations of less than 25 parts per billion (ppb) of blood serum or plasma no penalty is recommended. For concentrations of 25 ppb or greater but less than 50 ppb of blood plasma or serum the recommended penalty is a written warning, the placement of the horse on the Veterinarians List with removal from list only after a blood test confirms that the concentration is below 25 ppb of blood plasma or serum.

Testing shall be paid by the owner(s) of the horse.

Concentrations of 50 ppb or greater in blood plasma or serum have a recommended “B” penalty.

Cocaine

A3

If it is determined by the State Veterinarian/Equine

Medical Director; the Stewards, or the Racing Authority that the finding of cocaine or morphine was unintentional and not based upon an attempt to affect the outcome of a race, the Stewards or Racing Authority may elect to assign a Class B penalty to the trainer.

Codeine

Colchicine

Conorphone

Corticaine Ultracain 2 A

Corticotrophind 3 B Peptide hormone involved in the stress response.

Cortisone Cortone, etc.

Cromolyn Intel

Crotetamide

Cyamemazine Tercian 2 A

Cyclandelate Cyclospasmol 3 A

Cyclizine Merazine

Cyclobarbital Phanodorm

Cyclobenzaprine Flexeril 4 B

Cyclofenil effects, same classification as Testolactone on Human

Olympic Guidelines -selective estrogen receptor modulator (SERM).

Cyclomethycaine Surfacaine 4 C

Cyclothiazide Anhydron, Renazide

Cycrimine Pagitane

Cyproheptadine Periactin 3 B

Danazol Danocrine 3 B

Dantrolene Dantrium 4 C

Darbepoetin Aranesp 1 A

Darbepoetin (depo)

Erythropoietin Link - Bone marrow stimulant

(Erythropoiesisstimulating agents are medications which stimulates the bone marrow to make red blood cells).

Decamethonium Syncurine 2 A

Dehydrochloromethylte stosterone

Dembroxol

(Dembrexine) Sputolysin

Demoxepam

Deoxycorticosterone Percortin, DOCA, Descotone, Dorcostrin

Deracoxib Deremaxx

Dermorphin

Desipramine Norpromine, Pertofrane 2 A

Desonide Des Owen

Desoximetasone

Topicort 4 C

Desoxymethyltestostero ne

Detomidine

Dormosedan

Dexamethasone Azium, etc. 4 C

Dextromethorphan

Dextromoramide Palfium, Narcolo

Dextropropoxyphene Darvon 3 B

Dezocine Dalgan 2 A

Diamorphine

Diazepam Valium

Diazoxide Proglycem

Dibucaine Nupercainal, Cinchocaine

Dichloralphenazone Febenol, Isocom

Dichlorphenamide Daramide

Diclofenac Voltaren, Voltarol 4 C

Dicumarol Dicumarol

Diethylpropion Tepanil, etc.

Diethylthiambutene Themalon 2 A

Diflorasone Florone, Maxiflor

Diflucortolone Flu-Cortinest, etc.

Diflunisal

Digitoxin Crystodigin 4 B

Digoxin Lanoxin

Diisopropylamine

Consistent with nitroglycerine

Dihydrocodeine Parcodin

Dihydroergotamine

Dihydrotestosterone

(17β-hydroxy-

5aandrostan-3-one)

Steroid - endogenous androgen sex steroid and hormone.

Dilorazepam

Briantum

Diltiazem Cardizem

Dimefline

Dimethisoquin Quotane 4 B

Dimethylsulfoxide

(DMSO)

Domoso

Diphenadione 5 C

Diphenhydramine Benadryl

Diphenoxylate Difenoxin, Lomotil

Diprenorphine M50/50

Dipyridamole Persantine

Dipyrone

Novin, Methampyrone 4 C

Disopyramide

Norpace 4 B

Divalproex

Depakote 3 A

Dixyrazine

Esucos 2 A

Dobutamine

Dobutrex 3 B

Donepezil

Aricept 1 A

Dopamine

Intropin

Doxacurium

Nuromax 2 A

Doxapram

Dopram 2 A

Doxazosin

Doxefazepam

Doxans

Doxepin Adapin, Sinequan 2 A

Doxylamine

Decapryn

Dromostanolone

Drolban 3 B

Droperidol Inapsine, Droleptan, Innovar-Vet (with Fentanyl)

Drostanolone 3 A Steroid

Duloxetine

Dyclonine

Dyclone

Dyphylline

Edrophonium

Tensilon 3 B

Eletripan

Relpax

Eltenac

Enalapril (metabolite enaloprilat) Vasotec

Enciprazine

Endorphins

Enkephalins

Ephedrine

Epi-dihydrotestosterone androgenic metabolite of

Epibatidine

Epinephrine

Epitestosterone endogenous steroid and an epimer of the androgen sex hormone testosterone.

Endogenous, stereoisomer of a B substance.

EPO-Fc

Erythropoietin Link -fusion protein in human blood.

EPO-mimetic peptides

(EMP):

Ergoloid mesylates

(dihydroergocornine mesylate, dihydroergocristine mesylate, and dihydroergocryptine mesylate)

Ergonovine Ergotrate

Ergotamine Gynergen, Cafergot, etc. 4 B

Erthrityl tetranitrate Cardilate

Erythropoietin (EPO) Epogen, Procrit, etc. 1 A

Esmolol Brevibloc

Esomeprazole Nexium

Estazolam Domnamid, Eurodin, Nuctalon

Eszopiclone

Etacrynic acid 3 C

Etamiphylline

Etanercept Enbrel

Ethacrynic acid Edecrin

Ethamivan

Ethanol

Ethchlorvynol Placidyl

Ethinamate Valmid 2 A

Ethoheptazine Zactane

Ethopropazine Parsidol

Ethosuximide Zarontin

Ethotoin Peganone 4 B

Ethoxzolamide Cardrase, Ethamide

Ethylaminobenzoate

(Benzocaine) Semets, etc.

Ethylestrenol Maxibolin, Organon

Ethylisobutrazine Diquel 2 A

Ethylmorphine Dionin

Ethylnorepinephrine Bronkephrine

Ethylphenidate

Etidocaine Duranest 2 A

Etifoxin Stresam 2 A

Etiocholanolone etiocholane steroid as well as an endogenous 17-ketosteroid that is produced from the metabolism of

Etizolam Depas, Pasaden

Ethamsylate

Etodolac Lodine 3 B

Etodroxizine Indunox

Etofenamate

Consistent with other non-

FDA approved NSAIDs

Etomidate

Etorphine HCl M99

Exemestane effects, same classification as Testolactone on Human

Famotidine Gaster, etc.

Felbamate Felbatol

Felodipine Plendil 4 B

Fenarbamate Tymium 2 A

Fenbufen Cincopal

Fenclozic acid Myalex 2 B

Fenfluramine Pondimin 2 A

Fenoldopam Corlopam 3 B

Fenoprofen Nalfon 3 B

Drug/Substance

Trade Name(s)

Drug Class

Penalty Class

Special Notation

Note.

Fenoterol

Berotec 3

Fenspiride

Respiride, Respan, etc

Fentanyl

Sublimaze 1

Fentiazac

Fexofenadine

Allegra

Fibroblast Growth

Factors (fgfs), Hepatocyte Growth

Factor (HGF), Insulin-like Growth Factor-1

(IGF-1) and its analogues, Mechano

Growth Factors (mgfs), Platelet-Derived

Growth Factor (PDGF), Vascular-Endothelial

Growth Factor (VEGF) and any other growth factor affecting muscle, tendon or ligament protein synthesis/degradation, vascularization, energy utilization, regenerative capacity or fiber type switching.

Cardiac, Muscle effects - a family of peptide cytokines that are important in the regulation of many tissues.

Lack FDA approval; no legitimate use in race horse.

Firocoxib

Flecainide

Idalon 4

Floctafenine

Idalon, Idarac

Fluanisone

Sedalande 2

Fludiazepam

Erispam 2

Fludrocortisone

Alforone, etc. 4

Flufenamic acid

Flumethasone

Flucort, etc. 4 C

Flumethiazide

Ademol

Flunarizine

Sibelium

Flunisolide

Bronilide, etc. 4 C

Flunitrazepam Rohypnol, Narcozep, Darkene, Hypnodorm

Flunixin

Banamine 4 C*

Fluocinolone

Synalar

Fluocinonide

Licon, Lidex 4 C

Fluopromazine

Psyquil, Siquil

Fluoresone

Caducid 2 A

Fluorometholone

FML 4 C

Fluoroprednisolone

Fluoxetine

Prozac 2 A

Fluoxymesterone

Halotestin

Flupenthixol

Depixol, Fluanxol

Fluphenazine Prolixin, Permitil, Anatensol, etc.

Flupirtine

Katadolone 3 A

Fluprednisolone

Alphadrol

Flurandrenolide

Cordran

Flurazepam

Dalmane

Flurbiprofen

Froben

Fluspirilene

Imap, Redeptin

Fluticasone Flixonase, Flutide

Flutoprazepam Restas

Fluvoxamine Dumirox, Faverin, etc.

Formebolone

Formestane effects, same classification as Testolactone on Human

Formoterol Altram 3 B

Fosinopril Monopril

Fosphenytoin Cerebyx 3 B

Fulvestrant effects, same classification as Testolactone on Human

Olympic Guidelines -

Estrogen receptor antagonist antineoplastic agent.

Furazabol

Furosemide Lasix N/A

Gabapentin Neurontin 3 B

Galantamine Reminyl 2 A

Gallamine Flaxedil 2 A

Gamma Aminobutryic

Acid (GABA) Carolina Gold

Gepirone

Gestrinone

GH-Releasing Peptides

(ghrps), e.g., alexamorelin, GHRP-6, hexarelin and pralmorelin (GHRP-2)

Anabolic Effects - a synthetic GH secretagogue.

Anabolic agent lacking FDA approval

Glutethimide

Doriden

Glycopyrrolate

Robinul 4 C

Growth Hormone

Releasing Hormone

(GHRH) and its analogues, e.g., CJC-

1295, sermorelin and tesamorelin

Anabolic Effects - peptide analogue of growth hormone-releasing hormone which is used as a diagnostic agent to assess growth hormone secretion for the purpose of diagnosing growth hormone deficiency.

Growth Hormone

Secretagogues (GHS), e.g., ghrelin and ghrelin mimetics, e.g., anamorelin and ipamorelin

Anabolic Effects - hunger hormone, appetiteenhancing and anabolic effects.

Guaifenesin (glycerol guiacolate)

Gecolate

Guanabenz

Wytensin 3 B

Guanadrel

Hylorel 3 A

Guanethidine

Ismelin 3 A

Halazepam

Paxipam 2 A

Halcinonide

Halog 4 C

Halobetasol

Ultravate 4 C

Haloperidol

Haldol 2 A

Haloxazolam

Somelin

Harpagoside

Devil’s Claw Plant

Hemoglobin glutamers Oxyglobin Hemopure

Heptaminol Corofundol

Heroin

Hexafluorenium Myalexen

Hexobarbital Evipal

Hexocyclium Tral

Hexylcaine Cyclaine

HIF activators (e.g.

Argon, xenon)

Cardiovascular Effects - a key mediator of oxygen homeostasis that was first identified as a transcription factor that is induced and activated by decreased oxygen tension.

Higenamine

Homatropine Homapin

Homophenazine Pelvichthol

Hydralazine Apresoline

Hydrochlorthiazide Hydrodiuril

Hydrocodone

(dihydrocodienone) Hycodan

Hydrocortisone

(Cortisol) Cortef, etc.

Hydroflumethiazide Saluron

Hydromorphone Dilaudid

Hydroxyamphetamine Paradrine 1 A

Hydroxyzine Atarax

Hypoxia-inducible factor (HIF) activators

1 A Blood doping agent

Hypoxia-inducible factor (HIF) stabilizers

(e.g. IOX-2)

A

Blood doping agent

Ibomal Noctal

Ibuprofen Motrin, Advil, Nurpin, etc.

Ibutilide Corvert

Iloprost Ventavis

Imipramine Imavate, Presamine, Tofranil

Indapamide Diuretic 3 C

Indomethacin Indocin 3 B

Infliximab Remicade 4 B

Insulins

Hormone and Metabolic effects, same classification as

Testolactone on Human Olympic Guidelines - protein hormone that is used as a medication to treat high blood sugar.

Ipratropium

Irbesarten Avapro 3 A

Isapirone

Isocarboxazid Marplan

Isoetharine Bronkosol

Isoflupredone Predef 2x

Isomethadone

Isometheptene Octin, Octon

Isopropamide Darbid

Isoproterenol Isoprel

Isosorbide dinitrate Isordil

Isoxicam Maxicam

Isoxsuprine Vasodilan 4 C

Isradipine DynaCirc 4 B

Kebuzone

Ketamine

Ketalar, Ketaset, Vetalar 2 B

Ketazolam Anxon, Laftram, Solatran, Loftran

Ketoprofen

Orudis 4 C*

Ketorolac

Toradol

Labetalol

Normodyne 3 B

Lamotrigine

Lamictal

Lansoprazole

Lenperone

Elanone-V 2 A

Letosteine

Viscotiol, Visiotal

Letrozole

Levamisole

Levobunolol

Betagan

Levomethorphan

Levorphanol

Levo-Dremoran

Lidocaine

Xylocaine

Ligandrol

SARM

Lisinopril

Prinivil, Zestril 3 A

Lithium

Lithizine, Duralith, etc. 2 A

Lobeline

Lofentanil

Loflazepate, Ethyl

Victan

Loperamide Imodium 3 B

Loprazolam Dormonort, Havlane 2 A

Loratidine Claritin 4 C

Lorazepam Ativan 2 A

Lormetazepam Noctamid 2 A

Losartan Hyzaar

Loxapine Laxitane

Lubabegron

Luteinizing Hormone

(LH)

Hormone and behavioral effects - a hormone produced by gonadotropic cells in the anterior pituitary gland. In females, an acute rise of LH triggers ovulation and development of the corpus luteum. Used for behavior modification in colts / horses.

There should be no restriction/regulation in fillies and mares.

Mabuterol

Maprotiline Ludiomil

Mazindol Sanorex

Mebutamate Axiten, Dormate, Capla

Mecamylamine Inversine

Meclizine Antivert, Bonine

Meclofenamic acid Arquel 4 C

Meclofenoxate Lucidiril, etc. 2 A

Medazepam Nobrium, etc. 2 A

Medetomidine Damintor 3 B

Medroxyprogesterone 3 B Classification for all genders

Medrysone Medriusar, etc. 4 C

Mefenamic acid Ponstel 3 B

Meldonium Mildronate, et al

Meloxicam Mobic

Melperone Eunerpan 2 A

Memantine Namenda 2 A

Meparfynol Oblivon

Mepazine Pacatal

Mepenzolate Cantil

Meperidine Demerol

Mephenesin Tolserol

Mephenoxalone Control, etc.

Mephentermine Wyamine

Mephenytoin Mesantoin

Mephobarbital

(Methylphenobarbital) Mebaral

Mepivacaine Carbocaine

Meprobamate Equanil, Miltown

Meralluride Mercuhydrin

Merbaphen Novasural

Mercaptomerin Thiomerin 4 B

Mercumatilin Cumertilin

Mersalyl Salyrgan

Mesalamine Asacol 5 C

Mesoridazine Serentil

Mestanolone

Mesterolone

Metaclazepam Talis 2 A

Metandienone 3 A Steroid AAS lacking FDA approval

Metaproterenol Alupent, Metaprel

Metaraminol Aramine

Metaxalone Skelaxin 4 B

Metazocine

Metenolone 3 A Steroid AAS lacking FDA approval

Metformin

Methacholine

Methadone Dolophine

Methamphetamine Desoxyn 1 A4

Recommended Penalty B if testing can prove presence of only levo-methamphetamine is present in sample.

Methandriol

(Methylandrostenediol) Probolic

Methandrostenolone Dianobal

Methantheline Banthine 3 B

Methapyrilene Histadyl, etc.

Methaqualone Quaalude

Metharbital Gemonil 2 A

Methasterone

Methazolamide Naptazane 4 C

Methcathinone

Methdilazine Tacaryl

Methenolone Primobolan

Methixene Trest 3 A

Methocarbamol Robaxin

Methohexital Brevital

Methotrexate Folex, Nexate, etc. 4 B

Methotrimeprazine Levoprome, Neurocil, etc.

Methoxamine Vasoxyl

Methoxyphenamine Orthoxide 3 A

Methoxypolyethylene glycol-epoetin beta

(CERA)

Erythropoietin Link - an erythropoiesis-stimulating agent (ESA) indicated for the treatment of anemia associated with chronic kidney disease (CKD in adult patients on dialysis and patients not on dialysis.

Methscopolamine Pamine 4 B

Methsuximide Celontin

Methyclothiazide Enduron

Methyl-1-testosterone

Methylatropine

Methyldienolone

Methyldopa Aldomet

Methylergonovine Methergine

Methylhexanamine

(Methylhexaneamine) Geranamine

Methylnortestosterone

(Trestolone)

Methylphenidate

Ritalin

Methylprednisolone

Medrol 4 C

Methyltestosterone

Metandren 3 B

Methyprylon

Noludar 2 A

Methysergide

Sansert 4 B

Metiamide

Metoclopramide

Reglan

Metocurine

Metubine

Metolazone

Metomidate

Hypnodil 2 A

Metopon

(methydihydromorphin one)

Metoprolol

Lopressor

Metribolone 3 A Steroid

Mexazolam

Melex 2 A

Mexiletine

Mexitil

Mibefradil

Posicor

Mibolerone

Midazolam

Versed 3 B

Midodrine

Pro-Amiline

Milrinone

Minoxidil Loniten 3 B

Mirtazepine Remeron

Misoprostol Cytotec

Mitragynine Kratom 1 A

Mivacurium Mivacron 2 A

Modafinil Provigil

Moexipril (metabolite, moexiprilat) Uniretic

Mofebutazone

Molidustat

Blood doping agent

Molindone Moban

Mometasone Elocon

Montelukast Singulair

Moperone Luvatren 2 A

Morphine

A6

If it is determined by the State Veterinarian/Equine

Medical Director; the Stewards, or the Racing Authority that the finding of cocaine or morphine was unintentional and not based upon an attempt to affect the outcome of a race, the Stewards or Racing Authority may elect to assign a Class B penalty to the trainer.

Mosaprimine

Muscarine myo-inositol trispyrophosphate

(ITPP)

N-Butylscopolamine

Nabumetone Anthraxan, Relafen, Reliflex

Nadol Corgard

Naepaine Amylsine

Nalbuphine Nubain 2 A

Nalorphine

Nalline, Lethidrone

Naloxone

Narcan

Naltrexone

Revia 3 B

Nandrolone Nandrolin, Laurabolin, Durabolin

Naphazoline

Privine 4 B

Naproxen

Equiproxen, Naprosyn

Naratriptan

Amerge

Nebivolol

Nedocromil

Tilade 5 D

Nefazodone

Serzone 2 A

Nefopam

Neostigmine

Prostigmine

Nicardipine

Cardine

Nifedipine

Procardia 4 B

Niflumic acid

Nifluril 3 B

Nikethamide

Coramine 1 A

Nimesulide

Nimetazepam

Erimin 2 A

Nimodipine

Nemotop

Nitrazepam

Mogadon 2 A

Nitroglycerin

Nizatidine

Axid

Norandrosterone

Nandrolene Link - a detectable metabolite of nandrolone, an anabolic-androgenic steroid.

Norbolethone/Norbolet one

Norclostebol

Nordiazepam Calmday, Nordaz, etc.

Norethisterone

(norethindrone)

B all genders No known use in the horse

Norepinephrine

Norethandrolone

Nortestosterone

Nortriptyline Aventyl, Pamelor

Nylidrine Arlidin

Olanzepine Zyprexa

Olicerdine

A FDA approved opioid for humans

Olmesartan Benicar

Olsalazine Dipentum 5 C

Omeprazole Prilosec, Losec 5 D

Oripavine

Orphenadrine Norlfex 4 B

Ostarine

SARM

Oxabolone

Oxandrolone Anavar

Oxaprozin Daypro, Deflam

Oxazepam Serax

Oxazolam Serenal

Oxcarbazepine Trileptal 3 A

Oxilofrine

(hydroxyephedrine)

Oxprenolol

Trasicor

Oxycodone

Percodan 1 A

Oxymesterone

Oxymetazoline

Afrin 4 B

Oxymetholone

Adroyd, Anadrol

Oxymorphone

Numorphan 1 A

Oxyperitine

Forit, Integrin 2 A

Oxyphenbutazone

Tandearil 4 C

Oxyphencyclimine

Daricon 4 B

Oxyphenonium

Antrenyl 4 B

Paliperidone

Pancuronium

Pavulon 2 A

Pantoprazole

Protonix 5 D

Papaverine

Pavagen, etc. 3 A

Parecoxib

Paraldehyde

Paral 2 A

Paramethadione

Paradione 3 A

Paramethasone

Haldrone 4 C

Pargyline

Eutonyl 3 A

Paroxetine

Paxil, Seroxat

Peginesatide

Erythropoietin Link - an erythropoiesis-stimulating agent (ESA) indicated for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis.

Pemoline Cylert

Penbutolol Levatol 3 B

Penfluridol Cyperon

Pentaerythritol tetranitrate Duotrate

Pentazocine Talwin

Pentobarbital Nembutal 2 A

Pentoxyfylline Trental, Vazofirin 4 D

Pentylenetetrazol Metrazol, Nioric 1 A

Perazine Taxilan

Perfluorocarbons

Perfluorodecahydronop hthalene

Perfluorodecolin

Perfluorooctylbromide

Perfluorotripropylamin e

Pergolide Permax

Periciazine Alodept, etc.

Perindopril Biprel

Perlapine Hypnodin

Perphenazine

Trilafon

Phenacemide

Phenurone

Phenaglycodol

Acalo, Alcamid, etc. 2

Phenazocine

Narphen

Phencyclidine (PCP)

Sernylan

Phendimetrazine

Bontril, etc.

Phenelzine

Nardelzine, Nardil

Phenindione

Hedulin 5

D

Phenmetrazine

Preludin 1

Phenobarbital

Luminal

Phenoxybenzamine

Dibenzyline

Phenprocoumon

Liquamar 5

Phensuximide

Milontin 4

Phentermine

Iomamin 2

Phentolamine

Regitine

Phenylbutazone

Butazolidin

C*

Phenylephrine

Isophrin, Neo-Synephrine

Phenylpropanolamine

Propadrine

Phenytoin

Dilantin

Physostigmine

Eserine

Picrotoxin

Piminodine

Alvodine, Cimadon

Pimobendan

Pimozide

Orap 2 A

Pinazepam

Domar 2 A

Pindolol

Viskin

Pipamperone

Dipiperon 2 A

Pipecuronium

Arduan

Pipequaline

Piperacetazine

Psymod, Quide 2 A

Piperocaine

Metycaine

Pipotiazine

Lonseren, Piportil

Pipradrol

Dataril, Gerondyl, etc. 2 A

Piquindone

Pirbuterol

Maxair 3 B

Pirenzepine

Gastrozepin 5 C

Piretanide

Arelix, Tauliz

Piritramide

Piroxicam

Feldene 4 B

Plasma expanders (e.g.

Bycerol; intravenous administration of albumin, dextran, hydroxyethyl starch and mannitol)

No legit use in the racehorse. Lacks FDA approval.

Polyethylene glycol

Polythiazide

Renese

Pramoxine

Tronothaine 4 C

Prasterone

(dehydroepiandrostero ne, DHEA, 3βhydroxyandrost-5-en17-one)

Steroid - inactive endogenous steroid.

Prazepam

Verstran, Centrax

Prazosin

Minipress 3 B

Prednisolone

Delta-Cortef, etc.

Prednisone

Meticorten, etc. 4 C

Pregabalin

Lyrica 3 B Gabapentanoid

Prilocaine

Citanest 2 B

Primidone

Mysoline 3 B

Probenecid

Procainamide

Pronestyl 4 B

Procaine

Procaterol

Pro Air 3 A

Prochlorperazine

Darbazine, Compazine 2 A

Procyclidine

Kemadrin 3 B

Promazine

Sparine 3 B

Promethazine

Phenergan 3 B

Propafenone

Rythmol

Propanidid

Propantheline

Pro-Banthine 3 B

Proparacaine

Ophthaine 4 C

Propentophylline

Karsivan 3

Propiomazine

Largon 2

Propionylpromazine

Tranvet 2

Propiram

Propofol

Diprivan, Disoprivan 2

Propoxycaine

Ravocaine

Propranolol

Inderal

Propylhexedrine

Benzedrex 4

Prostanazol

Prothipendyl

Dominal

Protokylol

Ventaire

Protriptyline

Concordin, Triptil

Proxibarbital

Axeen, Centralgol

Pseudoephedrine

Cenafed, Novafed

Pyridostigmine

Mestinon, Regonol 3

Pyrilamine

Neoantergan, Equihist 3

Pyrithyldione

Hybersulfan, Sonodor 2

Quazipam

Doral

Quetiapine

Seroquel

Quinapril, Quinaprilat

Accupril

Quinbolone

Quinidine

Quinidex, Quinicardine

Rabeprazole Aciphex 5 D

Racemethorphan

Racemorphan

Raclopride

Ractopamine Paylean 2 A

Raloxifene

Estrogen effects, same classification as

Testolactone on Human

Olympic Guidelines -selective estrogen receptor modulators-SERMs.

Ramipril, metabolite

Ramiprilat Altace

Ranitidine Zantac

Remifentanil Ultiva

Remoxipride Roxiam

Reserpine Serpasil

Rilmazafone

Risperidone

Ritanserin

Ritodrine Yutopar 3 B

Rivastigmine Exelon 2 A

Rizatriptan Maxalt

Rocuronium Zemuron

Rofecoxib Vioxx

Romifidine Sedivet

Ropivacaine Naropin 2 A

Roxadustat (FG-4592)

Erythropoietin Link - HIF prolyl-hydroxylase inhibitor and thereby increases endogenous production of erythropoietin, which stimulates production of hemoglobin and red blood cells.

Salicylamide

Salicylate

Salmeterol

Scopolamine (Hyoscine) Triptone

Secobarbital

(Quinalbarbitone) Seconal

Selective Androgen

Receptor Modulators

(SARMs)

Selegiline Eldepryl, Jumex, etc.

Sertraline Lustral, Zoloft

Sibutramine Meridia 3 B

Sildenafil Viagra 3 A

Snake Venoms

Somatrem Protropin 2 A

Somatropin Nutropin 2 A

Sotalol Betapace, Sotacor 3 B

Spiclomazine

Spiperone

Spirapril, metabolite

Spiraprilat Renomax

Spironalactone Aldactone 4 B

Spironolactone Diuretic 3 C

Stanozolol Winstrol-V

Stenbolone

Strychnine

Succinylcholine Sucostrin, Quelin, etc.

Sufentanil Sufenta 1 A

Sulfasalazine Azulfidine, Azaline

Sulfondiethylmethane

Sulfonmethane

Sulforidazine Inofal 2 A

Sulindac Clinoril 3 B

Sulpiride Aiglonyl, Sulpitil 2 A

Sultopride Barnetil 2 A

Sumatriptan Imitrex 3 B

Synthetic cannabis Spice, K2, Kronic 1 A

Tadalasil Cialis 3 A

Talbutal Lotusate

Tamoxifen effects, same classification as Testolactone on Human

Olympic Guidelines -

Estrogen receptor antagonist antineoplastic agent.

Tandospirone

Tapentadol Nucynta 1 A

TCO2

Telmisartin Micardis 3 B

Temazepam Restoril 2 A

Tenoxicam Alganex, etc. 3 B

Tepoxalin

Terazosin Hytrin

Terbutaline Brethine, Bricanyl

Terfenadine Seldane, Triludan

Testolactone Teslac

Testolone

SARM

Testosterone

Tetrabenazine Nitoman 2 A

Tetracaine Pontocaine

Tetrahydrogestrinone

Tetrahydrozoline Tyzine 4 B

Tetrazepam Musaril, Myolastin

THC

(tetrahydrocannabinol)2 Drug of human abuse

1 A Drug of human abuse.

Thebaine

Theobromine

Theophylline Aqualphyllin, etc.

Thialbarbital Kemithal

Thiamylal Surital 2 A

Thiethylperazine Torecan 2 A

Thiopental Pentothal 2 A

Thiopropazate Dartal 2 A

Thioproperazine Majeptil 2 A

Thioridazine Mellaril 2 A

Thiosalicylate

Thiothixene Navane

Thiphenamil Trocinate

Thyroxine and thyroid modulators/hormones, including but not limited to those containing T4

(tetraiodothyronine/thy roxine), T3

(triiodothyronine), or combinations thereof.

Levothyroxine

FDA approvad but has (limited) legitimate use in care of racehorses.

Tianeptine Tianna, ZaZa Red, TD Red

Tiapride Italprid, Luxoben, etc.

Tiaprofenic acid Surgam 3 B

Tibolone 3 A Steroid - synthetic steroid. AAS lacking FDA approval

Tildronate Sodium Tildren 3 A Bisphosphonate

Tiletamine Component of Telazol

Timiperone Tolopelon

Timolol Blocardrin 3 B

Tocainide Tonocard

Tofisopam Grandaxain, Seriel

Tolazoline Priscoline 3 B

Tolfenamic Acid

Tolmetin Tolectin 3 B

Topirimate Topamax 2 A

Toremifene

Testolactone on Human Olympic Guidelines - Selective estrogen receptor modulator.

Torsemide

(Torasemide) Demadex

Tramadol Ultram

Trandolapril (and metabolite, trandolaprilat)

Tarka 3

Tranexamic acid

Tranylcypromine Parnate 2 A

Trazodone Desyrel 2 A

Trenbolone Finoplix 3 B

Tretoquinol Inolin 2 A

Triamcinolone Vetalog, etc. 4 C

Triamterene Dyrenium

Triazolam Halcion

Tribromethanol

Tricaine methanesulfonate Finquel

Trichlormethiazide Naqua, Naquasone 4 C

Trichloroethanol

Tricholoethylene Trilene, Trimar 2 A

Triclofos Triclos 2 A

Tridihexethyl Pathilon 4 B

Trifluomeprazine Nortran

Trifluoperazine Stelazine

Trifluperidol Triperidol 2 A

Triflupromazine Vetame, Vesprin

Trihexylphenidyl Artane

Trimeprazine Temaril

Trimetazidine

Testolactone on Human Olympic Guidelines - a drug for angina pectoris, the first cytoprotective anti- ischemic agent.

Trimethadione Tridione

Trimethaphan Arfonad 3 A

Trimipramine Surmontil 2 A

Tripelennamine PBZ 3 B

Triprolidine Actidil

Trometamol (Also known as tris hydroxymethyl aminomethane [THAM])

Tubocurarine (Curare) Metubin

Tybamate Benvil, Nospan, etc.

Urethane

Valdecoxib

Corrected to be consistent with all NSAIDS

Valerenic acid

Valnoctamide Nirvanyl

Valsartan Diovan 3 B

Vardenafil Levitra

Vedaprofen

Venlafaxine Efflexor

Veralipride Accional, Veralipril

Verapamil Calan, Isoptin

Vercuronium Norcuron

Viloxazine Catatrol, Vivalan, etc. 2 A

Vinbarbital Delvinol 2 A

Vinylbital Optanox, Speda

Warfarin Coumadin, Coufarin

Xylazine Rompun, Bay Va 1470 3 B

Xylometazoline Otrivin 4 B

Yohimbine

Zafirlukast Accolate

Zaleplon Sonata

Zeranol Ralgro 4 C

Ziconotide

Zileuton Zyflo

Zilpaterol hydrochloride Zilpaterol

Ziprasidone Geoden 2 A

Zolazepam

Zolmitriptan Zomig

Zolpidem Ambien, Stilnox

Zomepirac Zomax 2 B

Zonisamide Zonegran

Zopiclone Imovan

Zotepine Lodopin 2 A

Zuclopenthixol Ciatyl, Cesordinol 2 A

UNIFORM CLASSIFICATION OF FOREIGN SUBSTANCES

Version 14.4 (December, 2020)

PENALTY GUIDELINES

© ASSOCIATION OF RACING COMMISSIONERS INTERNATIONAL – 2020.

Association of Racing Commissioners International

2365 Harrodsburg Road, B-450, Lexington, Kentucky, United States www.arci.com

PENALTY CATEGORY “A”

http://www.arci.com/

The following are recommended penalties for violations due to the presence of a drug carrying a Category “A” penalty and for violations of

ARCI-011-015 and ARCI-025-015: Prohibited Practices:

LICENSED TRAINER:

1st Offense 2nd LIFETIME offense in any jurisdiction 3rd LIFETIME offense in any jurisdiction

• Minimum one-year suspension absent mitigating circumstances. The presence of aggravating factors could be used to impose a maximum of a three-year suspension

• Minimum three-year suspension absent mitigating circumstances. The presence of aggravating factors could be used to impose a maximum of license revocation with no reapplication for a three-year period.

• Minimum five-year suspension absent mitigating circumstances. The presence of aggravating factors could be used to impose a maximum of license revocation with no reapplication for a five-year period.

AND

• Minimum fine of $10,000 or 10% of total purse

(greater of the two) absent mitigating circumstances.

The presence of aggravating factors could be used to impose a maximum of $25,000 or 25% of purse

(greater of the two).

• May be referred to the Commission for any further action deemed necessary by the Commission.

Minimum fine of $25,000 or 25% of total purse

(greater of the two) absent mitigating circumstances.

The presence of aggravating factors could be used to impose a maximum of $50,000 or 50% purse (greater of the two).

May be referred to the Commission for any further action deemed necessary by the Commission.

Minimum fine of $50,000 or 50% of total purse

(greater of the two) absent mitigating circumstances.

The preence of aggravating factors could be used to impose a maximum of $100,000 or 100% purse

(greater of the two).

May be referred to the Commission for any further action deemed necessary by the Commission.

LICENSED OWNER:

1st Offense 2nd LIFETIME offense in owner’s stable any jurisdiction

3rd LIFETIME offense in owner’s stable in any jurisdiction

• Disqualification and loss of purse

AND

• Disqualification and loss of purse

AND

Horse shall be placed on the Veterinarian’s List for 180 days and must pass a commission-approved examination before becoming eligible to be entered.

• Disqualification, loss of purse and $50,000 fine

AND

Horse shall be placed on the Veterinarian’s List for 180 days and must pass a commission-approved examination before becoming eligible to be entered.

AND

• Horse shall be placed on the Veterinarian’s List for 180 • • days and must pass a commission-approved examination before becoming eligible to be entered.

• Referral to the Commission with a recommendation of a suspension for a minimum of 90 days.

PENALTY CATEGORY “B”

The following are recommended penalties for violations due to the presence of a drug carrying Category “B” penalty, for the detection of two or more

NSAIDs in a plasma/serum and/or urine sample, the detection of two or more corticosteroids in a plasma/serum and/or urine sample subject to the provisions set forth in ARCI-011-020(E) and ARCI-025-020(E) and for violations of the established levels for total carbon dioxide:

LICENSED TRAINER:

1st Offense 2nd offense (365-day period) in any jurisdiction 3rd offense (365-day period) in any jurisdiction

• Minimum 15-day suspension absent mitigating circumstances. The presence of aggravating factors could be used to impose a maximum of a 60-day suspension

• Minimum fine of $500 absent mitigating circumstances. The presence of aggravating factors could be used to impose a maximum fine of $1,000.

• Minimum 30-day…