Project Grant W911NF1710315

This Project Grant award of $687,304 from the National Science Foundation's Biological Sciences (CFDA 47.074) program will enable the South Dakota School of Mines and Technology to acquire a BioLector XTM microbioreactor system. This specialized equipment can simultaneously grow and monitor up to 48 microbial cultures, replicating large-scale industrial fermentation conditions at a small scale. It will facilitate advanced research across disciplines such as microbiology, biochemical engineering,...

This $464,923 federal Project Grant award was provided by the National Science Foundation's Engineering program (CFDA 47.041) to Clarkson University to host a new 3-year Research Experiences for Undergraduates (REU) site focused on Undergraduate Research in Sensor Development (Design, Manufacture, Analysis) and Implementation Pipeline (SDIP). The SDIP program aims to develop skilled leaders capable of addressing global challenges in fields such as public health, the environment, space,...

This $457,088 Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of imaging tools to improve the activity of endolysins, a promising alternative to traditional antibiotics for treating antibiotic-resistant bacterial infections. The key products and services to be delivered include: Synthesizing a panel of internally quenched substrates to assess the activity of...

This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $449,999.00 to develop a new class of wireless, free-floating biosensors that integrate electronic and biological sensing elements. The goal is to enable in situ, real-time monitoring of microbial dynamics within industrial fermentation environments. The sensors combine engineered microbes that emit bioluminescent signals in response to cellular stress and metabolite levels, with...

The National Science Foundation Division of Industrial Innovation awarded a $256,000 Project Grant to develop an automatic debridement device from August 1, 2021 through March 31, 2022. This Small Business Innovation Research Phase I award under the Engineering (47.041) program will support the creation of a product to automatically remove dead, damaged, or infected tissue. The NSF Directorate for Engineering seeks to foster innovation and excellence in engineering research, consistent with...

This federal Project Grant award of $957,000.00 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to Brown University. The award is intended to fund research aimed at "OPTIMIZING CLOPIDOGREL TO TREAT ALS" over a 2-year period from May 1, 2025 to April 30, 2027. As a leading academic research institution, Brown University has demonstrated extensive capabilities in delivering complex biomedical research and technical...

This National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems Project Grant, CFDA 47.041, provides $452,847 to Rensselaer Polytechnic Institute (RPI) for research on protein behavior in microgravity environments. The funding will enable RPI to develop predictive models for how protein solutions flow and undergo structural changes in the absence of solid surfaces, to further fundamental science and industrial applications like pharmaceutical...

The Defense Health Agency awarded a $490,602 Project Grant titled "CLINICAL-GRADE SPINAL CORD NEUROPROSTHESIS TO ALLEVIATE LOCOMOTOR DEFICITS IN PEOPLE WITH PARKINSON'S DISEASE" to the Ecole Polytechnique Federale De Lausanne (EPFL) in Switzerland. The grant, funded through the Military Medical Research and Development program (CFDA 12.420), supports EPFL's advanced biomedical research to develop a neuroprosthetic system to help manage locomotor deficits associated with Parkinson's...

This Project Grant award of $104,917 from the National Science Foundation's (CFDA 47.074) Biological Sciences program will support a team of undergraduate students at the University of Virginia in developing a low-cost treatment for exocrine pancreatic insufficiency. The students will design and build a probiotic that secretes synthetic pancreatic enzymes, with the goal of providing this treatment solution for the International Genetically Engineered Machines (iGEM) competition in synthetic...

This $500,000 Project Grant was awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) to William Marsh Rice University in Houston, Texas. The funding will support research to increase the secretion capacity of therapeutic cells, enabling them to produce higher levels of proteins to aid in disease treatment. The project aims to understand the mechanisms driving high antibody production in plasma cells and apply these insights to modify existing therapy-grade cells....