Early-phase study to evaluate MEK and MDM2 inhibition in patients with neurofibromatosis type 1 and premalignant and malignant peripheral nerve sheath tumors

Ended Project Grant Awarded Last action

Award ID
W81XWH2211120
Recipient
Awarding agency
Obligated
$1,393,487

Award facts

Assistance listing
12.420 Military Medical Research and Development
Completion date
Place of performance
Washington, DC 20010, USA

Award details come from USAspending.gov.

About this award

The Department of the Army Medical Command awarded $1.393 million to the Children's Research Institute under the Military Medical Research and Development federal grant program (CFDA 12.420) to support an early-phase study evaluating MEK and MDM2 inhibition in patients with neurofibromatosis type 1 and premalignant and malignant peripheral nerve sheath tumors. The Children's Research Institute will conduct the clinical trial through September 2026 to investigate medical solutions for peripheral nerve tumors, advancing the Military Medical Research and Development program's goals of transforming military and public health care through impactful biomedical research. As a sub-awardee, Children's National Medical Center will provide additional support for patient enrollment and treatment through the clinical trial.

Subawards

Subrecipient Amount Awarded
The University Of Texas Southwestern Medical Center Early Phase Study to Evaluate MEK and MDM2 Inhibition in Patients with Neurofibromatosis Type 1 and Pre-malignant and Malignant Peripheral Nerve Sheath Tumors $32,380
The Children's Hospital Of Philadelphia $165,000
University Of Alabama At Birmingham $102,477

Quick answers

Who received award W81XWH2211120?

W81XWH2211120 was awarded to Children's Research Institute by Medical Command (Department of the Army) on September 30, 2022.

How much is award W81XWH2211120 worth?

$1,393,487 has been obligated on W81XWH2211120.

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