Combinatorial helper-dependent adenoviral gene therapy for post-traumatic osteoarthritis
Ended Project Grant Awarded Last action
- Award ID
- W81XWH2210372
- Recipient
-
Baylor College Of Medicine UEI FXKMA43NTV21
- Awarding agency
-
Medical Command
Department of the Army, Department of Defense
- Obligated
- $10,087,552
Award facts
- Assistance listing
- 12.420 Military Medical Research and Development
- Completion date
- Funding
-
- $5,043,776.00 Federal
- $5,043,776.00 Non-federal
- Place of performance
- Houston, TX 77030, USA
Award details come from USAspending.gov.
About this award
The Department of the Army Medical Command awarded Baylor College of Medicine a $10,087,552 project grant from the Military Medical Research and Development program (CFDA 12.420) for the period of July 1, 2022 to June 30, 2026. The grant funds research on combinatorial helper-dependent adenoviral gene therapy for post-traumatic osteoarthritis. Specifically, Baylor College of Medicine and sub-awardees Cornell University ($401,517 each) will conduct preclinical studies to assess the prevention of pathological osteoarthritis features using this gene therapy model in animals. Outcome measures will include clinical observation, imaging, biomarker expression analysis, and histopathological assessment of treated joints. Toxicity and immune response to the viral vectors will also be evaluated. If proven effective in preclinical testing, this therapeutic approach may help translate healthcare innovations for service members and the public.
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Cornell University | $1,230,888 |
Quick answers
Who received award W81XWH2210372?
W81XWH2210372 was awarded to Baylor College Of Medicine by Medical Command (Department of the Army) on July 1, 2022.
How much is award W81XWH2210372 worth?
$10,087,552 has been obligated on W81XWH2210372: $5,043,776 in federal funding and $5,043,776 in non-federal funding.
On GovTribe
See this award's full record
- Every transaction and subaward
- The recipient's other awards and teaming partners
- Similar grant awards
- Ask GovTribe AI about this award