The National Institutes of Health (NIH) awarded a $656,148 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to the Trustees of Boston University, doing business as Boston University Medical Campus, to acquire a state-of-the-art BD FACSDiscover S8 spectral cell sorter with advanced imaging capabilities. This award will enable the Boston University Flow Cytometry Core Facility to replace its aging and unsupported cell sorting equipment, which is critical for the high-demand...
The National Institute of General Medical Sciences (NIGMS) awarded a $374,612 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Yale University to purchase an ECHO 650 Series acoustic liquid handling system. This system will replace an outdated instrument at the Yale Center for Molecular Discovery (YCMD), a core facility that provides genomic and drug screening services to over 40 NIH-funded investigators across 14 Yale departments. The ECHO acoustic...
This $15,083,516 federal Project Grant award from the National Institutes of Health (NIH) under the Construction Support program (CFDA 93.352) will fund the modernization of high and maximum containment research facilities at the National Emerging Infectious Diseases Laboratories (NEIDL) at Boston University. The grant aims to improve the operational efficiency and research capacity of the NEIDL's Biosafety Level 3 and 4 spaces to better support studies on high-consequence pathogens, including...
The National Institute of General Medical Sciences (NIGMS) awarded a $410,014 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to Trustees of Boston University to establish proof-of-concept for a new high-speed, real-time feedback-driven single particle tracking (RT-FD-SPT) fluorescence microscope with concurrent single-molecule FRET spectroscopic readout. The project aims to develop an advanced tracking instrument that can follow individual growth factor molecules in...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), will support a research project aimed at developing novel databases and metrics to measure the impact of biomedical tools and methods. The $248,893 award to Northeastern University, effective September 10, 2024 through August 31, 2028, will fund the creation of a knowledge base called BioToolKB that will identify and...
This $962,984 federal Project Grant awarded by the National Institute of Standards and Technology (NIST) under the Congressionally-Identified Projects program (CFDA 11.617) is intended to procure equipment and support the expansion of the Nubian Square Life Sciences Community Laboratory Program into the Roxbury neighborhood of Boston. The key activities include: 1) ordering equipment to provide hands-on training for the biomanufacturing program, 2) developing community relationships and...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $408,750.00 to develop synthetic oligonucleotide nanostructures that can precisely program interfacial interactions at immune system interfaces. The primary objectives are to: 1) Determine how cargo component spacing modulates receptor interactions and affects downstream immunomodulation; and 2) Elucidate the role of cargo...
This $639,794 federal grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports the acquisition of an Illumina NextSeq 2000 next-generation DNA sequencing instrument for the Design, Automation, Manufacturing, and Process (DAMP) Laboratory at Boston University. The new sequencing instrument will enable DAMP Lab researchers to study the genomic sequences of novel molecular tools they are developing, which can lead to improvements in drug design,...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $151,080 to the University of Massachusetts Dartmouth to acquire a circular dichroism (CD) spectropolarimeter instrument. The CD spectropolarimeter will enhance the university's biomedical research and education capabilities in areas such as characterizing the structures of chiral nanoparticles and biomolecules. This...
This $453,750 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) supports the development of advanced proteomics pipelines to improve the depth, throughput, and accuracy of mass spectrometry-based proteomics analysis. The research aims to address key challenges in sample preparation and data acquisition processes to enable more comprehensive profiling of proteomes, post-translational...
The federal Project Grant award of $248,756 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will fund the acquisition and utilization of a BioDoT Omnia automated liquid dispensing/handling system at the Analytical Instrumentation Core (AIC) facility at Boston Medical Center (BMC) and Boston University (BU). This system will enhance the efficiency and accuracy of high-throughput biological assays conducted by over 200 investigators and 10 NIH-funded projects across a broad spectrum of research areas, including pulmonary disease, infectious diseases, neurological diseases, vaccine development, diabetes, obesity, renal diseases, cardiovascular disease, and drug development. The award, with a performance period from May 15, 2025, to May 14, 2026, will enable researchers to conduct their projects more efficiently and with significantly improved precision and accuracy through the use of the automated liquid handling system.