Project Grant 2320685

Award Date 9/1/23
Completion Date 8/31/26
Dollars Obligated $640K
Funding Federal Agency
Office of Integrative Activities
Federal Grant Program
47.083
Assistance Type
Project Grant
Place of Performance
Boston, MA 02215, USA
Similar Awards
This Project Grant award for $1,035,125 from the National Institutes of Health (NIH) Office of the Director will fund the acquisition of a NovaSeq X Plus high-throughput DNA sequencing system to be housed at the Molecular Biology Core Facilities (MBCF) at the Dana-Farber Cancer Institute (DFCI) in Boston, MA. The award, provided under the NIH Research Infrastructure Programs (CFDA 93.351), will enable the MBCF to expand its genomics capabilities, allowing for cost-effective and rapid...
This federal Project Grant award, valued at $341,700.00, was provided by the United States Department of Agriculture's National Institute of Food and Agriculture (USDA-NIFA) under the Equipment Grants Program (CFDA 10.519). The grant will support the acquisition of a high-capacity Illumina NextSeq 2000 sequencing system that will be housed at the Institute of Marine and Environmental Technology (IMET) facility in Baltimore, Maryland. This shared-use equipment will primarily benefit...
Sequegenics LLC received a $251,073 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041). The grant supports development of low-cost and scalable methods for creating genomic databases using long-read next-generation DNA sequencing technologies. This aligns with the program's goals of fostering innovation in engineering research. The one-year project period runs from August 1, 2021 through July 31,...
This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting...
This $307,754 National Science Foundation Engineering Directorate project grant will fund the acquisition of a Nikon CSU-W1-SORA super-resolution spinning disk confocal microscope for Boston University. The microscope will enable new spatially resolved transcriptomics and multi-scale connectomics research techniques to study gene expression within cells and neural connectivity in brain networks. As a shared resource housed in BU's Photonics Center, the microscope is expected to serve nine...
This $320,861 federal Project Grant award from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) supports research to develop tools and methodologies for reading expanded genetic alphabets with bases beyond the standard A, T, G, and C. The key objectives are to: 1) improve the accuracy and generalizability of next-generation sequencing for unnatural base pairs using deep learning; 2) develop single-context sequencing models to measure polymerase...
This $447,747 Project Grant award from the National Science Foundation (NSF) Engineering Program (CFDA 47.041) to Trustees of Boston University will develop a novel plasmonic nanosensor system to detect two important classes of RNA molecules - microRNA (miRNA) biomarkers and SARS-CoV-2 viral RNA. The sensor platform uses DNA structures with nanoparticle probes that undergo conformational changes when binding to target RNAs, altering the plasmonic coupling signal which is detected via...
This Project Grant award of $408,007 from the National Science Foundation (NSF) Engineering program (CFDA 47.041) aims to develop a technology called "glycosequencing" that uses next-generation sequencing (NGS) to sequence and quantify glycan structures. The project will first identify an optimal set of lectins, biochemically characterize them, and prepare lectin barcoding for NGS. It will also build a training dataset using recombinant proteins produced in glycoengineered Chinese...
This $1,271,828 Project Grant was awarded by the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) to Northeastern University on September 1, 2024. The grant funds the development of fundamentally new approaches for genetically manipulating Clostridia bacteria, a diverse group with applications in sustainability and human health. Key objectives include overcoming limitations in Clostridia engineering, developing robust and portable functional genomics...
This $2,963,428 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop critical infrastructure components for interpreting genomic data. The project will create cutting-edge tools, workflows, and tutorials to make genome assembly and alignment methods more accessible to a wide audience of biologists for research in areas like biodiversity, evolution, and biogeography. Key planned outputs include: Development of high-quality...

This $639,794 federal grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports the acquisition of an Illumina NextSeq 2000 next-generation DNA sequencing instrument for the Design, Automation, Manufacturing, and Process (DAMP) Laboratory at Boston University.

The new sequencing instrument will enable DAMP Lab researchers to study the genomic sequences of novel molecular tools they are developing, which can lead to improvements in drug design, diagnostics, and biosensors. The DAMP Lab, an automated biology laboratory with advanced liquid handling capabilities, serves as a core facility for Boston University, the Boston area academic community, and industry partners. Adding the Illumina sequencer will expand the lab's services and make next-generation sequencing technology accessible to a broader set of researchers who may not have in-house expertise or wet lab facilities. No subawards are planned under this grant.

Generated 6/18/24, 4:34 AM