The National Institute of Mental Health (NIMH) awarded Duke University a Project Grant under the Mental Health Research Grants program (CFDA 93.242) to explore the cellular properties and circuit functional roles of human cortical interneurons. This $1,380,070 grant, awarded on September 6, 2024, will fund innovative research approaches using live brain specimens and advanced genetic tools to characterize the diversity, organization, and pathophysiology of inhibitory neural circuits in the human brain. The research aims to advance generalizable strategies for human cellular and circuit neuroscience while yielding a fundamental understanding of human interneurons and their role in brain disorders such as epilepsy, autism, and Alzheimer's disease. This grant supports Duke University's expertise in brain research, biomedical studies, and translational science to address critical gaps in our knowledge of human neural circuit design and develop targeted therapies for mental health conditions.
Generated 3/4/25, 7:47 AM