This $3.21 million cooperative agreement from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will fund research at the California Institute of Technology to develop whole-brain functional imaging and analysis tools to study sleep regulation in zebrafish. Over a three-year period from May 2022 to April 2025, the awardee will use two-photon selective plane illumination microscopy to record neuronal activity with single-cell resolution during natural and...
This federal Project Grant award of $378,726.00 from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) is focused on developing an innovative platform for measuring and quantifying social behaviors in animal models. The objective is to create a proof-of-concept solution for high-resolution 3D tracking of social behaviors in rats and mice using a novel deep neural network approach. Key products and services include: Design, validation, and optimization of...
This $1,999,635 project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke (NIH NINDS) will fund research into understanding feedforward and feedback signaling between neuronal populations. The grant was awarded to Albert Einstein College of Medicine on March 15, 2022 for a period ending February 28, 2025. The project aims to advance understanding of how feedforward and feedback signaling work together in the visual system by analyzing...
This $3,051,000 Trans-NIH Research Support Project Grant from the Department of Health and Human Services National Institutes of Health Office of the Director will fund research at Harvard Medical School from September 30, 2022 to July 31, 2025 to advance understanding of natural vision in the primate brain using machine learning techniques. Specifically, the researchers will test experimental designs to best predict responses of neurons in the inferotemporal cortex to natural images,...
This $7.6 million project grant from the National Institute of Mental Health, part of the Department of Health and Human Services, will fund research under the Mental Health Research Grants program (CFDA 93.242). Baylor College of Medicine will lead simultaneous high-throughput functional, transcriptomic, and connectivity profiling of neurons in the mouse visual cortex. The research aims to characterize the complex functional properties of neurons using in vivo two-photon imaging combined with...
The University of California, San Diego (UCSD) received a $1,378,728 Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) to conduct research on the neural circuits underlying biological motion perception and social engagement. The project aims to investigate the development of social brain networks in the micro glassfish (Danionella cerebrum) vertebrate model, leveraging its genetic amenability, small size, and optical...
This Project Grant award from the National Human Genome Research Institute (NHGRI), under the Human Genome Research federal grant program (CFDA 93.172), supports a project titled "Integrated Multimodal Phenotyping of Zebrafish Models of Human Cognitive Disorders". The $162,461 award, with a project period from Sep 2024 to Aug 2029, aims to generate knockout mutants for 61 transcriptional regulators associated with human cognitive disorders using CRISPR-based technologies. The principal...
This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $434,716 to the University of Oklahoma Health Sciences Center to develop a set of optical tools for capturing and interpreting high-speed recordings of neural activity across the entire zebrafish brain. The key objectives are to create fluorescent voltage sensors, optical microscopes, and signal processing algorithms that can simultaneously monitor millisecond-scale bursts of neural...
This $1,100,864 Project Grant was awarded by the National Institute on Drug Abuse (NIDA), part of the Department of Health and Human Services, under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant supports the development of techniques to integrate neural activity recordings and behavioral data with detailed anatomical connectivity data obtained through electron microscopy (EM) imaging. The goal is to create principled computational models that can relate neural structure...
This Project Grant from the National Science Foundation's Office of International Science and Engineering, under the CFDA program "Office of International Science and Engineering", provides $100,000 to develop a new computational framework for statistical inference of neuromodulation across species and spatial scales from large neural datasets. Vanderbilt University will analyze neural circuitry underlying changes in motivation, mood and alertness using a three-step approach. First,...