Project Grant RF1AG091579
- Federal Project Grant Award Summary The Johns Hopkins University received a $954,302 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded September 5, 2025, with a completion date of May 31, 2030. This grant supports basic research investigating a novel vascular pathway that regulates neuronal survival in neurodegenerative diseases. The research focuses on understanding the role of glycerophosphodiester phosphodiesterase 2 (GDE2), an enzyme...
- Summary Johns Hopkins University received a $405,049 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded May 15, 2025, with a completion date of May 14, 2027. The grant funds development of an automated, reproducible, and updateable national longitudinal dataset documenting Medicaid Home- and Community-Based Services (HCBS) waiver characteristics extracted from waiver application documents. This dataset will be made publicly available to...
- This $1,933,556 Project Grant awarded by the National Institute on Aging (NIA) under its Aging Research program (CFDA 93.866) will support research to assess the impact of hospital-based health information technology (hospital-HIT) on healthcare quality and equity for patients with Alzheimer's disease and related dementias (ADRD). The primary awardee, the University of Maryland, College Park, will conduct a ten-year longitudinal study to evaluate how hospital-HIT systems that promote care...
- Federal Grant Award Summary The Johns Hopkins University received a $618,410 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded February 1, 2026, with a completion date of January 31, 2029. The award supports the development of a deep learning-based miniature microscope designed to enable early detection and characterization of Alzheimer's disease (AD) pathology in preclinical models. The research addresses critical limitations in existing...
- Federal Grant Award Summary Brigham & Women's Hospital received a $3.69 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded on September 15, 2025, with a completion date of September 14, 2029. The award funds development of specialized large language models (LLMs) designed to extract Alzheimer's disease and related dementias (ADRD)-relevant clinical phenotypes from electronic health records (EHRs). The project addresses a critical...
- Federal Project Grant Award Summary The Johns Hopkins University received a $597,350 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded May 15, 2026, with a completion date of January 31, 2031. This grant supports the development of an oral glutamate carboxypeptidase II (GCPII) inhibitor therapeutic to improve peripheral nerve injury recovery in aging populations. The project addresses a critical clinical need by advancing...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded $198,164 through its Aging Research program (CFDA 93.866) to the University of Pennsylvania for an Individual National Research Service Award (NRSA) project commencing October 29, 2025, with completion targeted for May 31, 2027. This research training award funds a qualitative descriptive study examining dementia-friendly hospitalization practices with a focus on family caregiver inclusion. The project will deliver...
- Federal Project Grant Award Summary The National Institute on Aging awarded the University of Alabama at Birmingham a $5.06 million Project Grant (CFDA 93.866 – Aging Research) on September 15, 2025, for a four-year research initiative examining the impact of undiagnosed Alzheimer's disease and related dementias (ADRD) on healthcare utilization across geographic regions. The research project will integrate Medicare claims data with cognitive assessment data from the Reasons for Geographic and...
- This $2,497,615 federal Project Grant award, funded by the National Institute on Aging under the Aging Research program (CFDA 93.866), aims to evaluate the impact of new Medicare home health agency (HHA) payment policies on healthcare utilization and outcomes for Medicare beneficiaries with Alzheimer's disease and related dementias (ADRD). The project has three key objectives: 1) characterizing changes in the ADRD beneficiary population eligible for HHA services, 2) evaluating the effect of...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $1.08 million Project Grant to The Johns Hopkins University on August 1, 2025, under the Aging Research program (CFDA 93.866) to develop adeno-associated virus (AAV) vectors for selective manipulation of oligodendrocyte precursor cells (OPCs). The two-year project, concluding July 31, 2027, will generate novel OPC-selective AAV vectors and utilize them to investigate whether reactive transformation of OPCs surrounding...
The National Institute on Aging (NIA) awarded The Johns Hopkins University a $3.16 million Project Grant effective July 1, 2026 through June 30, 2030 under the Aging Research program (CFDA 93.866). The project, titled "Characterizing and Targeting Potentially Preventable Hospitalizations in Dementia," aims to reduce preventable hospital admissions among persons living with dementia (PLWD) through improved identification and understanding of hospitalization mechanisms. The research will develop more accurate algorithms for identifying potentially preventable hospitalizations (PPH) in dementia populations, recognizing that current diagnosis-based identification methods have limited accuracy in this vulnerable population due to the unique complexities of dementia care delivery involving cognitive, functional, and behavioral impairments. The project will advance evidence-based practices aligned with Medicare's Guiding an Improved Dementia Experience (GUIDE) care model by collecting perspectives from key stakeholders in dementia hospitalization, including caregivers, primary care providers, emergency department physicians, and health system representatives. Through this multi-stakeholder research approach conducted within Johns Hopkins Medicine and Atrium Health systems, the grant will generate actionable insights to reduce preventable hospitalizations and inform more effective dementia care delivery practices that can be implemented across the GUIDE program and broader healthcare settings.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.2m | 6/19/26 |