This Cooperative Agreement award from the National Institute on Drug Abuse (NIDA), under the federal Drug Use and Addiction Research Programs (CFDA 93.279), provides $2,983,510 to The Leland Stanford Junior University to conduct a two-phase research study on the use of deep transcranial magnetic stimulation (Deep TMS) to target the neural circuits associated with methamphetamine use disorder. The first phase (UG3) will enroll 30 participants to assess whether the specific Deep TMS protocol can...
This federal Project Grant award of $800,617 was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports the development and validation of neuromarkers - measurable, brain-based indicators of pathophysiology, risk, and resilience related to substance use disorders (SUDs). Specifically, the project aims to create a cross-validated neuromarker for drug craving, a core feature of SUDs, that can predict drug use and...
This Project Grant award, provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports a randomized clinical trial to evaluate the effectiveness of cognitive skills training interventions in improving outcomes for offenders with substance use disorders. The $3,226,170 award, with a project period from September 30, 2024 to May 31, 2029, aims to validate prior findings that matching specific cognitive-emotional deficits in...
The National Institute on Drug Abuse (NIDA) awarded a $1,585,991 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the Icahn School of Medicine at Mount Sinai in New York. The grant, awarded on May 1, 2025, will fund a double-blind randomized trial to evaluate the use of transcranial direct current stimulation (tDCS) combined with cognitive reappraisal training to reduce craving and cue-reactivity in individuals with cocaine use disorder. The study aims to explore...
This federal Project Grant award, valued at $882,816.00 and provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research aimed at advancing patient-centered approaches to understanding and treating co-occurring post-traumatic stress disorder (PTSD) and substance use disorders (SUDs). The key objectives of this 4-year project are to: 1) conduct new analyses on recovery-focused outcomes to evaluate the comparative...
This federal Project Grant award of $498,429.00, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), aims to identify the multi-modal factors that determine individual response to transcranial direct current stimulation (tDCS). The research team at the Children's Research Institute plans to apply state-of-the-art machine learning algorithms to a unique, multimodal dataset comprising structural MRI scans, functional MRI data...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $194,098 to the University of Vermont & State Agricultural College to conduct research aimed at advancing the implementation of evidence-based treatments for stimulant use disorder (StimUD) and other substance use disorders (SUDs) in harm reduction and community treatment settings. The key objectives of the 5-year project are to: (1)...
This Project Grant award of $288,107 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) is funding a 5-year predoctoral training program at the Scripps Research Institute. The program aims to develop a new generation of leaders equipped with technical skills and expertise in team science to translate research discoveries into potential treatments for substance use disorders. Key elements include: Mentorship from experts across...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,766,868 to The University of Texas at El Paso to validate a computational neurobiological model of costly drug-taking behavior centered on the striosomes of the dorsomedial striatum. The project aims to experimentally determine the role of the prelimbic-striosomal and striosomal-substantia nigra circuits in mediating the impact of craving on...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $818,513.00 to investigate the role of dopamine signaling in the basolateral amygdala on individual differences in reward-learning strategies and addiction-like behaviors. The 5-year study, starting on September 15, 2024, will focus on how Pavlovian reward-learning strategies, such as sign tracking versus goal tracking, predict unique...