Project Grant R56EY037692
- The National Eye Institute awarded a $615,979 Project Grant to Wayne State University to investigate a peptide-based combination therapy for restoring structure and function in the diabetic cornea. The grant falls under the Vision Research federal grant program (CFDA 93.867), which supports research aimed at understanding, preventing, and treating vision-related conditions and diseases. The primary objectives of this 4-year project are to: 1) establish the therapeutic role of TB4 and VIP as a...
- The National Eye Institute (NEI), part of the National Institutes of Health, awarded a $331,131 Project Grant under the Vision Research program (CFDA 93.867) to Physical Sciences Inc. (PSI) to develop and validate a high-resolution retinal imaging system with light flicker capabilities. This system aims to enable objective characterization of the photoreceptor response to light and quantify differences between normal and diseased eyes, particularly for patients with diabetic retinopathy. PSI,...
- The National Eye Institute (NEI), under the U.S. Department of Health and Human Services, awarded a $321,904 Project Grant to Proteris Biotech, Inc. through the Vision Research federal grant program (CFDA 93.867). The award, spanning August 1, 2025 to July 31, 2026, will fund the early development of the natural tear protein clusterin (CLU) as a novel approach to treat dry eye disease. The research aims to conduct non-GMP stability analysis of the drug substance and product, as well as perform...
- This $348,800 Project Grant was awarded on September 30, 2025 by the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), to N'Waii Inc. in Chicago, Illinois. The grant supports the development of a first-in-class mitochondrially targeted antioxidant drug candidate for the treatment of dry eye disease (DED), a condition affecting 20% of the global adult population. The drug candidate exhibits potent free radical scavenging capabilities and has demonstrated...
- The National Eye Institute (NEI), under the federal Vision Research grant program (CFDA 93.867), awarded a $595,302 project grant to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, for the period of April 1, 2025 to March 31, 2030. The project aims to investigate how glucose and lactate support photoreceptor health and function in order to develop new treatment strategies to prevent vision loss. Specifically, the researchers will determine whether the retinal...
- The National Eye Institute (NEI), under the federal Vision Research grant program (CFDA 93.867), awarded a $144,200 Project Grant to Pennsylvania State University's Milton S. Hershey Medical Center. The grant, effective June 1, 2025 through November 30, 2027, will fund research to characterize the molecular mechanisms underlying increased levels of the protein REDD1 in the retina due to diabetes, and explore alternative intervention strategies for preventing retinal complications caused by...
- The National Eye Institute (NEI), under the Department of Health and Human Services, awarded a $358,065 Project Grant to Revel Pharmaceuticals Inc., a biotechnology company in San Francisco, California. The grant is part of the NEI's Vision Research program (CFDA 93.867), which supports research to understand, prevent, and treat vision-related conditions and diseases. The goal of this Phase I grant is for Revel Pharmaceuticals to optimize lead drug candidates and demonstrate the activity of...
- The National Eye Institute (NEI) awarded a $482,067 Project Grant to Washington State University (WSU) on August 1, 2025 under the Vision Research federal grant program (CFDA 93.867). The grant supports research to develop novel nanotherapies for the targeted treatment of corneal neovascularization, a sight-threatening condition characterized by the growth of blood vessels into the cornea. The funding will enable WSU researchers to synthesize a unique trehalose-based dendrimer (TRE-D) that...
- The National Eye Institute (NEI), part of the Department of Health and Human Services, awarded a $113,274 Project Grant to the Texas A&M University System Health Science Center (TAMU HSC) under the Vision Research federal grant program (CFDA 93.867). The grant, awarded on June 1, 2025, aims to develop innovative surgical techniques using ultrafast, nonthermal lasers for treating vitreoretinal and posterior segment disorders of the eye. The project will evaluate the use of femtosecond...
- The National Eye Institute (NEI), under the U.S. Department of Health and Human Services, awarded a $730,000 Project Grant (CFDA 93.867 - Vision Research) to Human Cell Co, a for-profit biotech firm, to develop an optimized nerve growth factor (NGF) therapy for the treatment of dry eye disease (DED). The funding will support preclinical studies to evaluate the efficacy and mechanism of action of the company's proprietary NGF mutein (HC201) in improving tear film production and corneal...
The National Eye Institute (NEI) awarded a $896,046 project grant to The Schepens Eye Research Institute, Inc. in Boston, MA, under the Vision Research federal grant program (CFDA 93.867). The project, titled "Non-Invasive Electrical Stimulation as a Therapy for Diabetic Keratopathy", focuses on exploring the effectiveness of non-invasive transpalpebral electrical stimulation (TPES) as a treatment for diabetic keratopathy, a common complication in individuals with diabetes that results in nerve damage and symptoms such as dryness and pain in the eye. The research aims to understand how TPES can encourage corneal nerve regeneration and reduce painful sensations caused by nerve damage, with the goal of establishing TPES as a low-cost, effective treatment option for patients. The award period is from September 1, 2025 to August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $896.0k | 8/25/25 |