This Project Grant award, valued at $146,922.00 and issued on June 23, 2025, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports research at The Trustees of Columbia University in the City of New York, Health Sciences Division, to investigate how inhibiting the migration of immature neutrophils during obesity and weight loss affects...
This Project Grant award of $604,853 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) will fund research at Rockefeller University to elucidate the genetic determinants of human brown adipose tissue (BAT) function. The goal is to develop a better understanding of how BAT, which can protect against obesity and associated metabolic diseases, is regulated in humans. The research will leverage...
This federal Project Grant award of $1,600,000 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research at Beth Israel Deaconess Medical Center, Inc. (BIDMC) to develop a computational pharmacology approach for coordinating the regulation of multiple neuron types related to energy balance and satiety. The research aims to identify combinations of 2-10 ligands...
This $499,761 federal Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research conducted by the Albert Einstein College of Medicine in Bronx, NY. The award aims to define the connectivity between hypothalamic melanocortin peptide-expressing neurons and melanocortin 4 receptor (MC4R)-expressing neurons in the medial prefrontal...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $840,198 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Dana-Farber Cancer Institute, Inc. (Dfci) in Boston, MA. The goal of this 4-year project is to better understand the mechanisms of energy expenditure and adipose thermogenesis in mammalian systems, with a focus on the futile creatine cycle pathway. Key objectives include determining how...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $570,268 to the Albert Einstein College of Medicine to conduct research on the regulation of adipose tissue remodeling by the CCNC-Mediator. The research aims to study the cell-autonomous mechanisms and metabolic functions of enhanced white adipose tissue browning, as well as the cellular...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research, provides $1,152,102 to the University of California, Berkeley to study a potential new enhancer for the UCP1 gene, which is critical for activating thermogenesis in brown adipose tissue. The research aims to elucidate the role of this enhancer and an associated transcription factor in regulating UCP1...
The National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases awarded a $152,205 Project Grant to The Regents of the University of California San Francisco under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant funds research to investigate how vagal sensory neurons regulate autonomic responses to achieve metabolic homeostasis, and how downstream neuronal circuits in the nucleus tractus solitarius integrate...
This federal Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), will support research to investigate inhibitory neural circuits involved in the sympathetic regulation of metabolically important organs. The $350,000 award to Tulane University, granted on September 5, 2024, will fund studies to map inhibitory circuits controlling sympathetic output to the liver and adrenal gland,...
This Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to determine the structural basis of thermogenic mitochondrial respiratory complexes and their role in adipocyte function, obesity, and type 2 diabetes. The $813,511 award to Dana-Farber Cancer Institute, Inc. will fund a 4-year research project to: 1) Characterize the...