Project Grant R56AR084847
- Federal Project Grant Award Summary The Ohio State University received a $303,082 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective April 1, 2026, with an ultimate completion date of January 31, 2030. This award supports basic biomedical research investigating mast cell-specific signaling mechanisms in wound healing and scar formation. The research will elucidate a novel...
- Federal Project Grant Award Summary The Ohio State University Office of Sponsored Programs received a $433,125 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2026, with completion targeted for January 31, 2031. The award supports investigator-initiated research to understand metabolic reprogramming in reparative macrophages and its relationship to epigenetic...
- Federal Grant Award Summary The Ohio State University received a $153,169 Project Grant from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), awarded on August 15, 2025, with a completion date of July 31, 2027. This research initiative develops a rapid, non-invasive triage method using Raman spectroscopy and artificial intelligence to assess radiation exposure in mass casualty scenarios resulting from nuclear reactor...
- Federal Project Grant Award Summary The Ohio State University received a $410,893 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded March 1, 2026, with completion targeted for December 31, 2030. This award supports research to discover and characterize phosphonic acid natural products (NPs) through genomics-accelerated approaches. The project aims to establish fundamental genetic,...
- Federal Grant Award Summary The Ohio State University Office of Sponsored Programs received a $1.4 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective June 1, 2026, with completion targeted for May 31, 2030. The award funds research focused on enhancing chemotherapy response and reducing toxicity through microbiome and immune modulation. This research addresses Service Member health and medical advancement...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a Project Grant of $433,125 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct basic research on influenza A virus (IAV) pathogenesis and acute respiratory distress syndrome (ARDS) mechanisms. The two-year research initiative, awarded July 2, 2025, and extending through June 30, 2027, investigates how the viral PB1-F2 protein...
- Federal Project Grant Award Summary The Ohio State University received a $159,075 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), effective August 1, 2025, through July 31, 2027. The award funds the validation of the MIRAD (Micro-RNA Assay for Radiation Dosimetry) assay as a rapid biodosimetry tool for radiological and nuclear mass casualty triage applications in pediatric and geriatric...
- Federal Grant Award Summary The Ohio State University received a $433,125 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 1, 2026, with completion targeted for June 30, 2028. The project delivers a comprehensive subcellular proteome dataset mapping protein responses to influenza infection in intact human lung tissue. The research employs a novel promiscuous biotin-ligase...
- Federal Grant Award Summary Michigan State University's Henry Ford Health+Michigan State University Health Sciences partnership received a $1,403,056 Project Grant from the National Institutes of Health Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) awarded on April 23, 2026, with a completion date of April 22, 2029. This research initiative will identify the mechanisms of acute and long-term lung toxicity resulting from dermal exposure to vesicating chemical...
- Federal Grant Award Summary Fesariustherapeutics Inc. received a $349,892 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2027. The award supports development of DermisphereShield, an antimicrobial dermal regeneration template designed to address complex wound healing challenges in contaminated environments. The product targets critical clinical...
The Ohio State University received a $387,448 Project Grant from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) on June 22, 2026, with a completion date of May 31, 2027. The award funds development of innovative multifunctional wound dressings designed to treat chemical vesicant-induced skin injuries caused by agents such as sulfur mustard and nitrogen mustard. The research centers on engineering rapid-gelling antimicrobial hydrogel technology integrated with recombinant human MG53 (RHMG53) protein—a TRIM family protein with documented efficacy in cell membrane repair, wound healing acceleration, and anti-inflammatory effects through NF-KB pathway modulation. The primary deliverable is a shelf-stable, multifunctional therapeutic platform that simultaneously targets the three principal pathological mechanisms underlying vesicant-induced skin trauma: cell membrane damage, chronic inflammation, and secondary infection. Upon successful completion, these wound dressings are intended to serve as medical countermeasures that can be strategically stockpiled and rapidly deployed to address both civilian and warfighter medical needs in response to chemical vesicant exposure. The research addresses a critical clinical gap, as no approved therapeutics currently exist for managing vesicant-induced skin injuries.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $387.4k | 6/23/26 |