Project Grant R21AI194013
- This $153,169 federal Project Grant award from the National Institutes of Health (CFDA 93.310 Trans-NIH Research Support program) to The Ohio State University aims to develop a rapid, non-invasive method for assessing radiation exposure using Raman spectroscopy and artificial intelligence. The project will collect and analyze hair samples from mice exposed to controlled radiation doses to develop models for detecting exposure greater than 2 Grays and differentiating higher doses above 5 Grays....
- The National Institutes of Health (NIH) awarded a $156,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to Georgetown University on August 11, 2025. The project, titled "Development of a Multiomic Biodosimetry Panel for Use During Sepsis and Antibiotic Treatment", aims to develop a novel panel of metabolomic and gene expression biomarkers to rapidly screen and provide accurate dose reconstruction for individuals exposed to ionizing radiation. This panel will...
- The U.S. Department of Health and Human Services National Institutes of Health (NIH) awarded a $156,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to The Medical College of Wisconsin, Inc. The overall objective of this 2-year project, from August 1, 2025 to July 31, 2027, is to develop a panel of biomarkers that can discriminate between exposure of upper- and lower-body organs to radiation and predict health outcomes. The research aims to identify organ-specific...
- The National Institutes of Health (NIH) awarded a $350,000 Cooperative Agreement under the Trans-NIH Research Support program (CFDA 93.310) to The Medical College of Wisconsin, Inc. to deliver a field-ready, physically-based biodosimetry device capable of accurately estimating radiation doses in the range of 0-10 Gy within 0.5 Gy and estimating the homogeneity of irradiation exposure using in vivo measurements of human nails. The project aims to enhance biodosimetry capabilities by improving...
- This Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) aims to develop a non-invasive, painless biodosimeter using Fourier transform infrared attenuated total reflection (FTIR-ATR) imaging and statistical machine learning. The $197,930 award will fund research to expand upon preliminary data showing FTIR-ATR imaging can distinguish irradiated from control mice at doses as low as...
- This Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) totaling $157,000.00 is supporting research to develop a new class of radiation mitigating agents as medical countermeasures for hematopoietic acute radiation syndrome (H-ARS). The principal investigators from the collaborative research partnership between Henry Ford Health and Michigan State University Health Sciences will examine the mitigating effects of the small molecule...
- This $157,400 federal Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) is funding the development of an artificial intelligence (AI)-powered cytogenetic biodosimetry platform to rapidly detect chromosomal aberrations for radiation triage following radiological or nuclear incidents. The award to the Georgia TECH Research Corp, doing business as the Office of Sponsored Programs, will leverage...
- The University of Arizona was awarded a $542,053 Cooperative Agreement from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to develop a "Self-Administered Multiplex Radiation Indicator (SAMURAI) Kit for Field Triage Biodosimetry". The SAMURAI Kit is a self-administered, paper-based vertical flow immunoassay system that can rapidly screen individuals for radiation exposure following a radiological or nuclear incident. The project aims to develop...
- The U.S. Department of Health and Human Services, National Institutes of Health (NIH) awarded a $155,857 Project Grant under the Trans-NIH Research Support (CFDA 93.310) program to Signablok, Inc. in Massachusetts. The funding supports the development of a novel medical countermeasure to mitigate potentially lethal acute radiation syndrome (ARS). The project aims to create a well-tolerable and effective first-in-class therapeutic that can be administered at least 24 hours post-radiation exposure...
- This federal Cooperative Agreement award of $583,468 was issued on September 16, 2025 by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The award is funding research to develop a small-molecule drug, referred to as MH01, that can stabilize the BRCA2-RAD51 complex to enhance DNA double-strand break repair and mitigate tissue damage caused by ionizing radiation exposure. The research aims to optimize the MH01 regimen, assess its...
The Ohio State University received a $159,075 Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to validate the MIRAD assay as a biodosimetry tool for radiation triage applications in pediatric and geriatric populations. The MIRAD assay is a rapid test that can estimate radiation doses from blood samples collected via a simple finger prick, providing results within 4 hours. This capability is critical for enabling timely administration of medical countermeasures and resource allocation in the aftermath of a radiological or nuclear incident. The project aims to further validate the MIRAD assay's performance in assessing radiation exposure levels, with a focus on the pediatric and geriatric demographics. The award period runs from August 1, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $159.1k | 7/30/25 |