Project Grant R44NS139774
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $306,463 Project Grant under the CFDA 93.286 "Discovery and Applied Research for Technological Innovations to Improve Human Health" program to Dogpatch Medical LLC, effective September 1, 2025 through August 31, 2026. The grant funding supports the development of PASSIVECATH, an innovative microcatheter device designed for enhanced visibility and targeted drug delivery to the central nervous system...
- The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, awarded a $314,363 project grant to Arsenal Medical, Inc. in Waltham, MA. The grant, with an award date of August 1, 2025 and a completion date of July 31, 2026, will fund the development of an engineering model of the middle meningeal artery embolization procedure for treating chronic subdural hematoma (CSDH), a...
- This $654,593 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, aims to develop structure-guiding tools to study the role of choline in the development of congenital hydrocephalus. The key objectives are: 1) Determine the structures of the FLVCR1 and FLVCR2 choline transporters using cryo-electron microscopy to generate functional...
- This federal Project Grant award of $2,353,206.00, issued by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the role of the SPAK-NKCC1 protein complex in the choroid plexus and its contribution to blood-CSF barrier dysfunction in vascular contributions to cognitive impairment and dementia (VCID). The research aims to fill the...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $373,778 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Research Foundation For The State University Of New York (Stony Brook University) to establish a novel vasculature database and analytical platform for mouse brain vasculature. The project aims to develop topology-preserving vessel segmentation algorithms and advanced statistical models...
- The federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $439,239 to the Beckman Research Institute of the City of Hope to fabricate and evaluate the feasibility of a novel neurosurgical device termed "REMIDE" for the efficient and consistent removal of intracerebral hematomas using minimally invasive, image-guided...
- The U.S. National Institute of Neurological Disorders and Stroke (NINDS) awarded a $125,685 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Leland Stanford Junior University (Stanford University). The funding will support the development of an injectable hydrogel with an integrated urokinase plasminogen activator (uPA) motif and plasmid DNA (pDNA) platelet-derived growth factor B (PDGFB)-lipoplexes to be loaded into the...
- This $108,512 Project Grant was awarded on February 15, 2025 by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), which administers the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The grant was awarded to the University of Illinois to develop a low-cost surgical instrument for real-time navigation and external ventricular drain (EVD) placement to address the global disparity in access to neurosurgery,...
- This $307,202 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports research by Wayne State University to optimize shunt catheters for the treatment of hydrocephalus. The award, with an initial term from January 15, 2024 to January 14, 2026, will fund experimental, computational, and analytical studies focused on biomechanics, human injury tolerance, anthropomorphic test device evaluation, and computational modeling...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $431,750 to support a collaborative research project between Henry Ford Health and Michigan State University Health Sciences. The project aims to overexpress the CYP2C11 enzyme in peri-lesion astrocytes using an adeno-associated virus (AAV) vector, in order to increase cerebral...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $306,315 project grant under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, to Wynnvision LLC in Virginia. The project aims to develop an amine gradient (AG) silicone ventricular catheter (VC) for use in ventriculoperitoneal shunting (VPS) procedures to treat hydrocephalus. The key goals are to validate the antimicrobial efficacy, resistance to host cell and biofilm adhesion, and mechanical performance of the AG silicone VC technology, building on prior successful in-vitro studies. If successful, this innovation could help address the high failure rates associated with current VPS procedures, which are commonly caused by infections and cell obstruction. The project is scheduled to be completed by April 30, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.3k | 9/22/25 |