The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $537,508 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program to The Research Foundation For The State University Of New York, doing business as Stony Brook University. This 5-year award (12/1/2024 - 11/30/2029) supports research to elucidate the role of endogenously formed zinc protoporphyrin (ZnPP) in brain damage following intracerebral hemorrhage...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $299,982 to Unandup, LLC to evaluate the safety and efficacy of their novel magnetic infusion platform for accelerating alteplase delivery to acute ischemic stroke clots. The project aims to use an in vivo rat model to support an Investigational Device Exemption (IDE) application for...
This $498,995 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports the development of a highly parallelized interferometric near-infrared spectroscopy (INIRS) platform for the real-time, non-invasive measurement of cerebral blood flow. The research aims to address the limitations of current stroke diagnosis and monitoring techniques...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding the development of an innovative portable device to rapidly detect and monitor traumatic brain injury (TBI) biomarkers. The $332,122 award to Hemex Health Inc. aims to create a point-of-care diagnostic platform that can quickly analyze whole blood samples to identify elevated...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA Program 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders, provides $1,819,210.00 to the University of Chicago to test a novel biopharmaceutical agent, Sanguinate, for mitigating cerebral infarct growth in acute ischemic stroke. The goal is to evaluate Sanguinate's ability to boost collateralization and deliver oxygen to ischemic brain tissue, with the...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a 2-year, $423,500 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to Wayne State University in Detroit, MI. The objective of this high-risk, high-reward research project is to investigate the use of remotely administered hypothermia (RAH) to the spleen as a novel neuroprotective therapy for ischemic stroke. The research aims to determine if suppressing splenic...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $423,500 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to the Augusta University Research Institute, Inc. The objective is to develop and evaluate engineered exosomes carrying neuron-targeting peptides and a therapeutic protein (neuroglobin) for treating ischemic stroke. The research will: 1) characterize the engineered exosomes and assess their...
This federal Project Grant award of $221,120.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to improve neural progenitor (NP) survival and migration for the treatment of neurodegenerative diseases and brain injuries. The project investigates the potential of adult central nervous system (CNS) endothelial cells to express developmental...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $1,386,770 to VON Vascular, Inc. to develop a novel aspiration pump for neurointerventional procedures. The goal is to create an improved aspiration pump that can increase first-pass revascularization rates and reduce medical waste, compared to existing market-leading devices....
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to advance the development of prognostic and monitoring biomarkers for neutrophil-driven secondary brain injury in spontaneous intracerebral hemorrhage (SICH). The $704,313 award, with a project period from December 1, 2024 to November 30, 2026, will support research to define and...