This $319,000 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports the development of a novel liquid methadone dispensing device and smart container system called MOUD-EID by Sano Healthcare Consultants, LLC. The key products and services to be delivered include: (A) an inner-container that precisely dispenses up to 30-days of liquid methadone using an electromechanical, volumetric-control system; (B) a...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Abuse and Addiction Research Programs (CFDA 93.279) provides $318,257 to Cari Health, Inc. to develop a therapeutic monitoring system (TMS) for remote medication compliance tracking of methadone treatment for opioid use disorder (OUD). The key products and services to be delivered include: 1) Integrating an electrochemical sensor, microneedle array, and data pipeline into a prototype wearable...
The National Institute on Drug Abuse (NIDA) awarded a $636,344 Cooperative Agreement under the Drug Use and Addiction Research Programs (CFDA 93.279) to Cari Health, Inc. (doing business as Clinical Addiction Recovery Institute) to develop and commercialize a new science-based approach for methadone dosing adjustments. The project aims to use novel, non-invasive point-of-care technology to evaluate small blood samples and quickly determine an individual patient's methadone rate of metabolism,...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $295,906 to Addinex Technologies, Inc. to integrate and assess a closed-loop medication management system for opioid pain management in ambulatory patients with extremity fractures being discharged from the emergency department. The project aims to adapt Addinex's existing medication dispensing platform to work within a hospital pharmacy setting,...
The National Institute on Drug Abuse (NIDA) awarded Labsys LLC a $643,948 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a wearable continuous drug monitoring device for opioid use disorders (CDM-MOUD). The goal is to create a low-cost, painless patch that uses microneedle technology to monitor medication levels in the interstitial fluid and provide real-time insights into treatment effectiveness. In Phase I, the team will engineer an alpha prototype...
The National Institute on Drug Abuse (NIDA) awarded a Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to New York University School of Medicine to simulate the impact of expanding methadone treatment access through office-based prescribing and pharmacy dispensing in New York State. The $683,583 award, spanning August 2024 to July 2026, will use an agent-based modeling approach to estimate how these policy changes could influence methadone initiation, retention,...
The National Institute on Drug Abuse (NIDA) awarded a $800,000 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to Tenvos Inc., a minority-owned and woman-owned technology company. The grant will support the development of a software-based medical device (SAMD) integrated into a smartphone application that can detect opioid use through voice analysis. The proposed solution aims to enable patients in outpatient opioid use disorder (OUD) treatment to remotely test for...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the federal Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,594,478 to the University of Massachusetts Medical School (UMass Medical) to conduct a prospective, observational trial on using digital biomarkers from wearable sensors to understand craving patterns and develop digital phenotypes related to treatment outcomes for opioid use disorder (OUD). The project will monitor N=300 participants...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on developing a novel, non-pharmacological whole body vibration (WBV) device to treat opioid use disorder (OUD). The primary goal is to evaluate the translational relevance of pre-clinical and clinical findings demonstrating that WBV can ameliorate neuronal, neurochemical, and behavioral effects of opioid dependence, including anxiety and...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $591,752 to Oprems LLC to develop and evaluate a digital platform for screening patients who receive prescribed opioid medications for potential risk of opioid misuse and overdose. The key products and services to be delivered under this grant include integrating the screening tools and process developed by Oprems' existing...