Project Grant R43DA061397
- This federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Abuse and Addiction Research Programs (CFDA 93.279) provides $318,257 to Cari Health, Inc. to develop a therapeutic monitoring system (TMS) for remote medication compliance tracking of methadone treatment for opioid use disorder (OUD). The key products and services to be delivered include: 1) Integrating an electrochemical sensor, microneedle array, and data pipeline into a prototype wearable...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is supporting the development of a software-based medical device (SAMD) for detecting opioid use through voice analysis. The $800,000 award to Tenvos Inc., a minority-owned and woman-owned technology company, aims to advance the company's AI-driven solution that can enable patients to remotely test for opioid use and securely share results with...
- This federal Project Grant award of $144,252 was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award will support the development of novel, personalized solutions to the substance use disorder epidemic, as well as the training of a highly skilled workforce to address this critical public health challenge. The key products and services to be delivered through this 5-year grant include: Development of a novel...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $319,000 to Sano Healthcare Consultants, LLC for the development of a novel liquid methadone dispensing device and smart container system. The project aims to address key barriers in accessing medication for opioid use disorder (MOUD) by creating a low-cost, single-device solution that enables remote supervised use, telehealth, and behavioral...
- The National Institute on Drug Abuse (NIDA) awarded a $326,410 Project Grant to Berkshire Biomedical Corporation under the Drug Use and Addiction Research Programs (CFDA 93.279) to evaluate the benefits of a hand-held, automated, personalized oral liquid dispensing system for take-home methadone medication management for patients with opioid use disorder. This 1-year study aims to assess the clinical outcomes and feasibility of using this technology to improve patient access, treatment...
- This $586,936 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports the development of a low-cost, disposable urine test strip that can rapidly and quantitatively measure substance use disorder (SUD) medication drugs and their metabolites. The award recipient, Vitan-Biotech LLC, will create a point-of-use lateral flow assay (LFA) test strip that leverages innovative signal amplification technology to...
- This Project Grant award, in the amount of $404,078, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports the development of the DOVE device, an innovative wearable sensor system and software that can automatically detect opioid overdoses and provide real-time guidance to facilitate effective reversal interventions. The project aims to create a device-agnostic solution that can predict and monitor fatal...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $386,452 to Electronic Biosciences, Inc. to develop rapid fingerstick diagnostics for opioid and stimulant use disorders. The award aims to address the escalating public health crisis of opioid and stimulant overdoses, which claimed over 107,000 lives in 2022. The funding supports Electronic Biosciences' work on advanced nanopore-based analytical...
- The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), has awarded a $4,710,576 Cooperative Agreement to Mebias Discovery Inc. to develop a new chemical entity, MEB-1170, for the treatment of opioid use disorder (OUD). The project will conduct preclinical studies in rodents and non-human primates to evaluate the efficacy of MEB-1170 as a maintenance medication for OUD, and will also include a Phase 1 multiple ascending dose clinical trial...
- This Project Grant award of $454,251 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports the development of a novel approach for long-term monitoring of opioid-induced changes in neural population activity and opioid receptor gene expression in individual mice. The research team at the University of Pennsylvania will develop "erasable" reporter molecules that can translocate from neurons into the peripheral...
WEARABLE CONTINUOUS DRUG MONITORING DEVICE FOR PERSONAL MEDICATIONS IN OPIOID USE DISORDERS (CDM-MOUD) - ABSTRACT LABSYS'S OBJECTIVE IS TO CREATE A TRANSFORMATIVE WEARABLE PATCH, DESIGNED AS A LOW-COST CONTINUOUS DRUG MONITORING DEVICE FOR OPIOID USE DISORDERS (CDM-MOUD). OUR STATE-OF-THE-ART PATCH UTILIZES A MICRONEEDLE-SO FINE THAT IT IS PAINLESS-TO MONITOR MEDICATION LEVELS DIRECTLY WITHIN THE INTERSTITIAL FLUID, A TECHNIQUE THAT HAS BEEN SHOWN TO RELIABLY MIRROR BLOOD CONCENTRATIONS. OUR PROPRIETARY DETECTION METHOD CAN SECURE BOTH SENSITIVITY AND SPECIFICITY OF THE OPIOIDS AT CONCERNED CONCENTRATION RANGE. THIS APPROACH PROMISES A LEAP FORWARD IN MANAGING OUD BY PROVIDING UNINTERRUPTED INSIGHTS INTO THE EFFECTIVENESS OF TREATMENT PROTOCOLS. IN OUR UPCOMING PHASE I RESEARCH, OUR SPECIFIC AIMS FOCUS ON ENGINEERING AN ALPHA PROTOTYPE WITH FENTANYL SENSING CAPABILITY. THIS INITIAL MODEL WILL INTEGRATE OUR PATENTED ELECTROCHEMICAL SENSOR TECHNOLOGY WITH LOW-POWER ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY, COUPLED WITH SEAMLESS WIRELESS COMMUNICATION FOR REAL-TIME DATA TRANSMISSION. THIS ENDEAVOR IS NOT JUST ABOUT TECHNOLOGY; IT'S ABOUT PEOPLE. AS WE REFINE OUR PROTOTYPE, EVALUATING CRITICAL FACTORS SUCH AS ACCURACY, RESPONSE TIME, AND DEVICE LONGEVITY, WE WILL ENGAGE WITH THE POTENTIAL CUSTOMERS. WE WILL TAILOR THE PATCH TO THE NUANCED NEEDS OF CUSTOMERS TO ENSURE OUR PRODUCT ALIGNS WITH THE REAL-WORLD DEMANDS. OUR VISION EXTENDS INTO PHASE II, WHERE WE WILL FURTHER ADAPT OUR PROTOTYPE FOR BROADER CLINICAL USE, PURSUING THE FDA'S "BREAKTHROUGH DEVICES PROGRAM" PARTICIPATION TO MEET RIGOROUS REGULATORY STANDARDS, AND CLINICAL TRIALS TO ENSURE THE HIGHEST STANDARDS OF PATIENT SAFETY AND PRODUCT EFFICACY. LABSYS'S MISSION THROUGH THIS PROJECT IS TO EMPOWER INDIVIDUALS BATTLING OUD WITH DISCREET, CONTINUOUS HEALTH MONITORING, AS ESSENTIAL AS A GLUCOSE MONITOR. OUR PRODUCTS WILL EMPOWER PATIENT-CENTERED CARE, FOSTERING BETTER OUTCOMES AND FACILITATING A MORE PERSONALIZED APPROACH TO TREATMENT. WE BELIEVE THAT OUR CDM-MOUD HAS THE POTENTIAL TO REVOLUTIONIZE OPIOID TREATMENT AND OFFER A NEW BEACON OF HOPE FOR MILLIONS AFFECTED BY THE OPIOID CRISIS, PARTICULARLY, DISADVANTAGED POPULATIONS IN LOW-RESOURCE SETTINGS.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $55.0k | 4/10/25 | ||
| Not listed | $0 | 9/26/24 | ||
| Not listed | $0 | 9/26/24 | ||
| Not listed | $294.5k | 8/20/24 | ||
| Not listed | $294.5k | 8/20/24 |