Project Grant R44AR086730
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is developing the X-Visual, a sensor to track fracture healing in cannulated screws used for hip fracture fixation. The $299,999 award to Aravis Biotech LLC will cover the design, computational modeling, and initial testing of this innovative device that can non-invasively measure screw bending...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award to Reselute, Inc. provides $998,921 to develop a novel implantable orthopedic medical device and procedure to reduce recovery duration and infection risks associated with severe traumatic fractures of the long bones. The project aims to advance a 3D-printed, antibiotic-releasing intramedullary nail to improve upon current standard-of-care implants that are prone to...
- This federal Project Grant award of $306,722 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The funding supports Penderia Technologies Inc., a small business joint venture located in Eugene, Oregon, to fabricate and characterize a distal femoral fracture fixation plate that features an implantable, battery-free, wireless sensor. This sensor will enable...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $594,000 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to Poly Orth International to develop a 3D-printed "Skin and Bone Integrated Pylon" (SBIP) for direct skeletal attachment of limb prostheses. The research aims to demonstrate the feasibility and safety of this novel prosthetic technology, which can potentially benefit patients who...
- This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $306,871 to Flex Orthopaedics, Inc. to develop a compliant intramedullary stem that can improve the longevity of revision total knee arthroplasty (RTKA) implants. The objective of this project is to create an RTKA implant stem design that can accommodate rotational motion about...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) provides $830,712 to Peer Technologies PLLC to commercialize a novel lumbar interbody fusion technology. The project, titled "SMART CAVITY CREATOR DRILL FOR LUMBAR INTERBODY FUSION: DIRECT TO PHASE II," aims to develop a sensor-enabled, articulated drill bit ("Smart Cavity...
- This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program totaling $295,247 will support the development of an innovative medical technology for localized and sustained antibiotic treatment of periprosthetic joint infection. Specifically, the awardee Reselute will design, develop, and validate a proof of concept for an orthopedic spacer implant with a novel porous medium capable of controlled antibiotic elution over 180 days. The implantable...
- This federal Project Grant award of $646,506 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is supporting the development of dual-action nanoparticle-loaded microparticles for the treatment of osteoarthritis (OA). The research aims to create innovative nanoparticle-based therapeutics that can stimulate the anabolic activity of chondroprogenitors to enhance cartilage...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded Panorama Research Incorporated, doing business as Panorama Research Inc., a $275,765 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to develop an antibody-based therapy for reducing scarring and fibrosis following joint surgeries. The project aims to improve the delivery and tissue residence of a lead humanized antibody that inhibits collagen fibril formation, thereby...
- The National Science Foundation (NSF) awarded a $295,000 SBIR Phase I Project Grant under the Technology, Innovation, and Partnerships (CFDA 47.084) program to Biodynamik, a small business located in Lake Forest, CA. The grant supports the development and testing of a novel implantable system that leverages distraction osteogenesis as a treatment for diabetic foot ulcers (DFUs). The project aims to design and develop a low-profile, transverse tibial transport device with an active mechanical...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $314,362 to Reselute, Inc. to develop the ReselutionTM Hindfoot Intramedullary Nail. The goal of this project is to create a combination implant that integrates structural support with sustained local antibiotic delivery to prevent infections while stabilizing fractures and fusions in patients with diabetic Charcot osteoarthropathy. The key objectives are to: (1) develop a prototype of a shelf-stable prefabricated antibiotic-loaded nail, (2) establish a manufacturing process, (3) complete preclinical verification testing, and (4) validate the device's safety and efficacy in a large animal model. This project employs a rigorous pre-clinical research and development strategy to prepare for regulatory submission and redefine the standard of care for high-risk patients with hindlimb arthropathies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $314.4k | 9/3/25 |