This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is developing the X-Visual, a sensor to track fracture healing in cannulated screws used for hip fracture fixation. The $299,999 award to Aravis Biotech LLC will cover the design, computational modeling, and initial testing of this innovative device that can non-invasively measure screw bending...
This Project Grant award from the National Science Foundation (NSF), under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, supports the development and validation of a novel, projection-based surgical navigation platform by Illuminant Surgical Inc. The $274,865 award, effective January 15, 2024, aims to create a system that projects visual anatomical references and guidance directly onto a patient's skin during minimally invasive spinal procedures. This is expected to...
This Project Grant award of $605,253 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award will support research to investigate the mechanical crosstalk between the intervertebral disc and adjacent facet joints during spinal degeneration and potential mitigation through disc repair. The study will utilize large animal models and human cadaveric tissues...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $294,992 to Illuminant Surgical Inc. to develop and test a deformable registration pipeline for the company's PRISM surgical navigation tool. The goal is to improve the robustness of PRISM's markerless registration process by accounting for skin surface deformations that can occur between preoperative imaging and surgery. The award will fund two aims: (1) developing the deformable...
The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $752,620 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to The Washington University. The grant, awarded on September 20, 2024, with a completion date of August 31, 2026, will support the development of alginate hydrogels with tethered insulin-like growth factor 1 (IGF-1) mimetic peptides. These engineered hydrogels are designed to enhance the...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award to Reselute, Inc. provides $998,921 to develop a novel implantable orthopedic medical device and procedure to reduce recovery duration and infection risks associated with severe traumatic fractures of the long bones. The project aims to advance a 3D-printed, antibiotic-releasing intramedullary nail to improve upon current standard-of-care implants that are prone to...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $306,735 Project Grant under CFDA 93.286, the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program, to Briteseed, LLC, a small disadvantaged business in Chicago, IL. The grant supports the development of a novel multispectral Kerrison rongeur (MKR) surgical instrument capable of detecting dura and nerve roots during spinal surgery. The MKR will integrate an...
This $252,906 National Science Foundation project grant supports the development of scalable manufacturing methods for peptide amphiphile molecules by Amphix Bio Inc. The goal is to advance a safer and more affordable alternative to recombinant proteins currently used in spinal fusion surgeries. Over 500,000 such surgeries are performed annually in the U.S. to treat back and neck pain.
While peptide amphiphiles show promise for reducing biological dose needs and offering consistent outcomes,...
This federal Project Grant award, valued at $172,766 and provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), aims to establish the utility of using real-time patient-reported and biometric data to prognosticate and stratify lumbar spine patients, and to define the value proposition for implementing these methods.
The key objectives of the 5-year project, funded under the NIAMS Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA...
The University of California, Davis received a $600,475 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The purpose of this award is to develop a collagen-based scaffold modified with specific integrin ligands and extracellular vesicles derived from placental mesenchymal stem cells. This engineered scaffold is intended to recruit and guide...