Project Grant 2136259

Award Date 2/15/22
Completion Date 1/31/23
Dollars Obligated $295K
Federal Grant Program
47.084
Assistance Type
Project Grant
Place of Performance
Durham, NC 27701, USA
Similar Awards
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award to Reselute, Inc. provides $998,921 to develop a novel implantable orthopedic medical device and procedure to reduce recovery duration and infection risks associated with severe traumatic fractures of the long bones. The project aims to advance a 3D-printed, antibiotic-releasing intramedullary nail to improve upon current standard-of-care implants that are prone to...
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $305,000 to Novaurum Biosciences Incorporated, a small business in Somerville, MA, to develop a novel mammalian cell-based nano-biological coating for implantable medical devices. The project aims to address the critical issue of implant-related infections, which cost the U.S. healthcare system over $8.6 billion annually, by creating a...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) Project Grant award of $305,000 to Resonantia Diagnostics, Inc. aims to develop a rapid point-of-care diagnostic platform capable of identifying pathogens and determining their antimicrobial susceptibility within 60 minutes. The project will focus on advancing an acoustic sensing technology to: (1) demonstrate accurate antimicrobial susceptibility testing at low pathogen loads, (2)...
This Project Grant award, provided by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), is funding the development of a novel implantable medical device for reconstructive surgery. The total award amount is $275,000 and the period of performance is from September 15, 2024 to August 31, 2025. The key objectives of this Phase I SBIR project are to design, fabricate, and validate a prototype implantable device that can integrate...
This Project Grant award of $275,000 from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a platform for detecting genetic antibiotic resistance motifs that can predict current and future susceptibility to therapeutics. The award recipient, Informuta, Inc., will establish the feasibility of leveraging mutational signatures found in bacterial DNA to predict antibiotic resistance status. The project aims to...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $295,000 to Biodynamik, a for-profit organization located in Lake Forest, CA, aims to develop a novel implantable system for treating diabetic foot ulcers (DFUs). The project objectives are to design and test a low-profile implantable device that can transversely distract or retract a cut tibia bone segment in a programmable manner, leveraging the process of distraction...
This $305,000 SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) was granted to Giant Biosystems Inc., a small disadvantaged business, to develop a rapid point-of-care antimicrobial susceptibility testing (AST) kit. The key products to be delivered include: A novel microfluidic platform for rapid (6-9 hours) and precise AST, providing actionable results faster than current methods (3-5 days). This will enable...
This National Science Foundation (NSF) Cooperative Agreement award under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,000,000.00 in funding to Nostopharma LLC, a woman-owned small disadvantaged business, to develop an innovative sustained-release, biodegradable drug delivery platform using anti-inflammatory nanoparticles and Hedgehog pathway antagonists. The goal is to create a localized, targeted medication delivery system to address unmet medical needs for...
The National Science Foundation awarded a $750,000 Project Grant to Rutgers, The State University under the Engineering program (CFDA 47.041) from September 1, 2022 to August 31, 2025. The grant funds research to develop an injectable nanoparticle therapy to restore strength and length to damaged tendons and ligaments. Specifically, the university will investigate combining a thermosensitive polymer and crosslinking agent to stabilize joints by quickly strengthening and returning tissues like...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,811 to Anova Biomedical, Inc. will fund the development of a novel 3D printing resin for producing personalized, elastic, and bioresorbable vascular grafts. The goal is to advance treatment options for cardiovascular disease, a leading cause of medical spending and death in the U.S. The project consists of three objectives: 1) developing and optimizing the 3D printing...

This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program totaling $295,247 will support the development of an innovative medical technology for localized and sustained antibiotic treatment of periprosthetic joint infection. Specifically, the awardee Reselute will design, develop, and validate a proof of concept for an orthopedic spacer implant with a novel porous medium capable of controlled antibiotic elution over 180 days. The implantable antibiotic-eluting spacer aims to enable ambulatory recovery for joint replacement patients with infection while providing extended-release anti-microbial treatment to potentially eliminate the need for further surgery or prolonged intravenous antibiotics. By locally delivering antibiotics at the infection site for a sustained duration, this technology seeks to improve patient outcomes and reduce healthcare costs associated with unresolved joint infections.

Generated 1/7/24, 3:32 AM