Project Grant R44AI131963

This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $305,000.00 to Resonantia Diagnostics, Inc. to develop a transformative diagnostic platform for rapid identification and antimicrobial susceptibility testing of pathogens. The project aims to achieve three key technical objectives: (1) demonstrate accurate antimicrobial susceptibility testing at very low pathogen loads, (2) validate testing...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 aims to develop a platform for detecting genetic antibiotic resistance motifs that can predict current and future susceptibility to therapeutics. The project will establish the feasibility of leveraging mutational signatures in bacterial DNA to identify antibiotic resistance status, including the potential for rapid development of multi-drug resistance. This approach...

The National Science Foundation awarded PZA Innovation LLC a $270,509 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop reliable pyrazinamide susceptibility testing at neutral pH. The grant period runs from January 1, 2022 through October 31, 2023. Under this award, PZA Innovation LLC will deliver products and services focused on advancing science and engineering research and innovation leading to breakthrough technologies for national and...

This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to RT Microdx Inc. provides $274,362 to develop a novel molecular diagnostic platform for detecting respiratory diseases like strep throat. The platform aims to provide laboratory-quality accuracy for at-home use by non-healthcare professionals. Key technical objectives include optimizing the sensitivity of the platform's pH-sensitive polymer detection mechanism and ensuring robust performance at...

This $298,045 Project Grant award from the National Institutes of Health's National Center for Advancing Translational Sciences (CFDA 93.350) aims to establish and develop a high-throughput screening (HTS) assay to identify novel bacterial DNA gyrase poisoning inhibitors. The key products and services to be delivered under this one-year award include: Developing a unique HTS assay to rapidly discover bacterial DNA gyrase poisoning inhibitors from small molecule libraries. This assay will...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support the development of a novel universal rapid test for HIV diagnosis. IGE Immunodiagnostics & Therapeutics, LLC, a minority-owned small business, will receive $294,948 to adapt their existing HIV ELISA test into a 5th generation antigen/antibody combination rapid test format. The goal is to create a simple, rapid,...

Controlpoint Inc. was awarded a $256,000 Project Grant from the National Science Foundation to develop a rapid, single-use, point-of-care lateral flow device for detecting kennel cough pathogens. The one-year award, made under the NSF Technology, Innovation, and Partnerships program, will support test validation, prototype manufacturing, and clinical evaluation to demonstrate the feasibility of detecting multiple bacteria and viruses associated with kennel cough in a single diagnostic test....

L2 Diagnostics LLC received a $293,142 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 21, 2025, with a completion date of August 31, 2027. The award supports development of a rapid diagnostic test (RDT) in lateral flow assay (LFA) format for detecting Babesia microti infection. The test targets BMGPI12 (BMSA1), a secreted protein released into the...

This $256,000 Project Grant from the National Science Foundation's Division of Industrial Innovation, under the Engineering program (CFDA 47.041), funds the development of a rapid, simple, and low-cost Salmonella detection and quantification test. Secure Food Solutions, Incorporated will optimize a multi-layer 96-well microplate method to demonstrate 90% sensitivity and specificity for Salmonella in raw poultry and processing environment samples within 15 hours without pre-enrichment. They...

Cobio Diagnostics Inc. received a $256,000 Project Grant award from the National Science Foundation on April 1, 2021 to support work concluding on March 31, 2022. The grant was awarded under the NSF's Engineering program (CFDA 47.041), which aims to improve quality of life and economic strength through engineering research and education. Specifically, the grant funds Cobio Diagnostics' "SBIR PHASE I: PHAGE-AMPLIFIED IDENTIFICATION AND ANTIMICROBIAL SUSCEPTIBILITY TEST" project. This...