This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $343,510 in funding to Theranova LLC, a veteran-owned medical device research and development company in San Francisco, CA. The grant supports the development and pilot evaluation of the SOLESTIM neuromodulation system, a portable, non-invasive device designed to treat dysmenorrhea (painful menstrual...
The National Institute of Child Health and Human Development (NICHD) awarded a $380,692 Project Grant under CFDA 93.865, the Child Health and Human Development Extramural Research program, to Mucommune LLC. The award will support the development of an ultrapotent anti-sperm antibody construct for a non-hormonal contraceptive intravaginal ring. Specifically, the project aims to formulate and characterize the release kinetics and activity/stability of the LAMH10 anti-sperm antibody in an...
The National Institute of Child Health and Human Development (NICHD) awarded a $1,514,498 Project Grant (CFDA 93.865) to Madorra Inc. to develop and evaluate the safety and efficacy of a novel, non-hormonal, at-home ultrasound device for the treatment of vulvovaginal atrophy (VVA). This two-year grant project aims to: 1) refine the Madorra Therapy System design to optimize ultrasound treatment settings based on prior clinical trial feedback, and 2) conduct a study demonstrating the device's...
The National Institute of Child Health and Human Development (NICHD) awarded a $383,114 SBIR Phase I project grant (CFDA 93.865) to Venova Technologies Inc., a women-led and minority-led medical device startup company, to advance the development of their patent-pending, non-hormonal, long-acting female contraceptive device. The project aims to continue iterative design and de-risk the technology through robust acceptance criteria, in preparation for future biocompatibility testing and clinical...
The National Institute of Child Health and Human Development (NICHD) awarded a $2,045,782 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Endomet Biosciences, Inc., a woman-owned small business located in Irvine, California. The grant aims to develop ENDO-205, a novel, non-hormonal therapeutic for the treatment of endometriosis, a prevalent and debilitating gynecological condition affecting approximately 10% of women worldwide. The project will advance...
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $474,946 to the University of Health Sciences and Pharmacy in St. Louis to develop a novel, non-hormonal contraceptive device. The award supports the design and fabrication of a dual-compartment vaginal device that enables women to administer a polymeric "smart fiber" mat and supplemental fluid to fortify...
The National Institute of Child Health and Human Development (NICHD) awarded a $759,944 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Nextgenjane Inc., a women's health startup, to commercialize a non-invasive diagnostic test for endometriosis. The funding will support validation studies of Nextgenjane's high-performance genomic assay for detecting endometriosis in the intended-use population of infertility patients. This diagnostic could enable...
The National Institute of Child Health and Human Development (NICHD) awarded a $291,440 Project Grant (CFDA 93.865) to Contraline, Inc. to support the development of ADAM AIR, a non-hormonal, vas-occlusive contraceptive device for men. This funding will enable advancements to the next-generation ADAM device, which can reduce manufacturing and procedural complexities while enabling on-demand reversibility. Key innovations include an implantable aerogel formulation that quickly swells into an...
The National Institute of Child Health and Human Development (NICHD) awarded a $2,283,054 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to CX Therapeutics, Inc. to develop a novel medical device for the treatment of cervical insufficiency in pregnant women. The proposed CX Device is designed to improve the efficacy and decrease adverse effects of traditional cervical cerclage procedures, which are used to prevent preterm birth in cases of cervical...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $309,251 to Expanse Bio LLC to develop an ex vivo microfluidic organ perfusion device for long-term culture and assessment of whole ovaries. The goal is to create a more physiologically relevant model for evaluating the ovotoxicity (ovarian damage) potential of drug candidates, particularly...