Project Grant R43GM157786
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $390,000 Project Grant to the Georgia State University Research Foundation Inc. The grant will fund a research program to develop a versatile, small molecule-based platform to map the "reader proteins" of glycosylation, which play critical roles in cell-cell communication, organism development, tumor metastasis, immune surveillance, and...
- This Project Grant award of $454,478 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports the development of advanced tools to study the glycan-protein interactome. The project, led by researchers at The Johns Hopkins University, aims to experimentally and computationally explore the interactions between gangliosides, a class of glycans found on cell surfaces, and their binding proteins. The research leverages...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development and commercialization of sialoglycan-recognizing probes (SGRPs). The $306,782 award, with a project period from September 1, 2025 to August 31, 2026, will enable Z Biotech, LLC to continue development and validation of six SGRPs (SGRP1, SGRP2, SGRP3, SGRP5, SGRP6, and SGRP8). These engineered probes leverage...
- The National Institute of General Medical Sciences (NIGMS) awarded a $382,500 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to Texas A&M Engineering Experiment Station (Tees) for the project "Role of Membrane Dynamics in Cell Surface Glycan Recognition" from January 1, 2025 to December 31, 2029. The goal of this project is to investigate how the spatial organization of glycan ligands on cell membranes influences glycobiology processes, and to develop...
- The National Institute of General Medical Sciences (NIGMS) awarded a $347,086 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) program to the University of California, San Diego (UCSD) for the project "PRECISION, FUNCTIONAL GLYCONANOASSEMBLIES THROUGH SUPRAMOLECULAR DESIGN". The project aims to develop a new synthetic approach for creating multivalent glycomolecules with atomic precision in order to study the structure-activity relationships involved in...
- The National Institute of General Medical Sciences (NIGMS) awarded Electronic Biosciences, Inc. a $350,000 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) program. The grant, awarded on June 5, 2025, supports the development and optimization of a novel enzyme-based, single-molecule protein sequencing system. This innovative platform leverages enzymatic processing and advanced bioinformatics to enable high-accuracy, high-throughput protein sequencing, addressing...
- The National Institute of General Medical Sciences (NIGMS) awarded a $315,000 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to Integrated Micro-Chromatography Systems, Inc. (IMCS) in Irmo, SC. The project aims to expand the commercial availability of recombinant glycosyltransferase enzymes and use them to synthesize 37 different glycosphingolipids from the globo-/isoglobo- and lacto-/neolacto-series. Additionally, the project will...
- The National Institute of General Medical Sciences (NIGMS) has awarded a 5-year, $471,019 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Georgia Tech Research Corporation (Georgia Tech Research Corp) to characterize extracellular glycoproteins and study their functions. The project aims to develop innovative mass spectrometry-based methods to comprehensively analyze glycoproteins on cell surfaces and in the secretome, as well as investigate the...
- The National Institute of General Medical Sciences (NIGMS) awarded a $417,400 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to the Pacific Northwest National Laboratory (PNNL) operated by Battelle Memorial Institute. The project aims to develop and advance mass spectrometry imaging (MSI) tools to enable more accurate and comprehensive chemical characterization of the glycome (the complete repertoire of cell carbohydrates) at tissue...
- The National Institute of General Medical Sciences (NIGMS) awarded a $283,805 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Invizyne Technologies, Inc. The project, titled "BIO-CLICK: A Cell-Free High-Throughput Platform for the Engineering of Enzymatic Group Transfer Reactions," aims to develop a novel cell-free, high-throughput platform to expedite the engineering of enzymes for biocatalytic "bioclick" reactions. The project...
The National Institute of General Medical Sciences (NIGMS) awarded a $306,710 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to Z Biotech, LLC to develop a glycan binding protein (GBP)-based glycosylation analysis system. The project aims to address limitations in current glycan structure analysis methods by: This work is expected to transform glycan structure analysis by providing a new low-cost platform for isomeric glycan structural analysis, opening up new opportunities for clinical and pharmaceutical research. The award period is from January 1, 2025 to December 31, 2025.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.7k | 12/17/24 |