This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $382,500 to Texas A&M Engineering Experiment Station (Tees) to conduct research into the role of membrane dynamics in cell surface glycan recognition.
The key objectives of the research project are to: 1) investigate how the spatial organization of glycan ligands on cell membranes influences glycobiology processes, integrating microscopy, spectroscopy, and computational modeling; and 2) develop analytical approaches using vibrational microscopy and machine learning to rapidly profile glycan patterns on cells. This research aims to advance the understanding of lectin-glycan interactions and enable better prediction of cellular processes, with potential to catalyze therapeutic advancements for glycan-associated diseases. The award period runs from January 1, 2025 to December 31, 2029.
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