This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), provides $2,297,901 to GMJ Technologies, Inc., a minority-owned small disadvantaged business, to develop a high-resolution native capillary zone electrophoresis system with inline UV and native mass spectrometry capabilities. This innovative analytical technology aims to enhance the characterization and quality control of protein...
This $350,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development and optimization of a novel, enzyme-based, single-molecule protein sequencing system by Electronic Biosciences, Inc. The objective is to create a rapid, reliable, and cost-effective platform that can accurately sequence proteins, including those with post-translational modifications, through the...
The National Institute of General Medical Sciences (NIGMS) awarded a $917,454 Project Grant under CFDA 93.859, Biomedical Research and Research Training, to Integral Molecular Inc. The grant supports the development of a novel Membrane Proteome Array (MPA) technology for specificity screening and profiling of biotherapeutics like monoclonal antibodies and CAR-T cell therapies. The MPA represents 93% of the human extracellular proteome expressed in native conformation, providing a more...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA program 93.859 Biomedical Research and Research Training provides $350,000 to Fluidispec LLC to develop a new microfluidic/nanofluidic sample preparation platform. The goal is to improve single-cell and low-input proteomics analysis by enabling efficient extraction of proteins from cells, removal of contaminants, and improved protein denaturation. This platform is expected to enhance...
The National Institute of General Medical Sciences (NIGMS) awarded a $297,664 Phase I Small Business Technology Transfer (STTR) grant to Blotting Innovations, LLC under the Biomedical Research and Research Training program (CFDA 93.859). The purpose of this project is to develop two innovative products for western blotting, a widely used protein analysis technique in biomedical research: A "Gelbrane" cassette that combines a polyacrylamide gel and transfer membrane in a single pre-cast...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) provides $295,561 to Biosensing Instrument Inc. to develop a commercial prototype of their Plasmonic Scattering Microscopy (PSM) technology. The PSM system aims to enable high-throughput, label-free quantification of membrane protein binding kinetics on single cells in their native cellular microenvironment. This represents a...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program provides $306,860 to Mixedlcmedia LLC, a small disadvantaged business, to develop and evaluate a prototype ultra-low flow liquid chromatography platform based on their proprietary porous layer open-tubular (PLOT) and monolithic nanocolumn technologies. The goal is to create a commercialization-ready LC system that enables deep proteomic...
The National Institute of General Medical Sciences (NIGMS) awarded a $300,518 Project Grant under CFDA Program 93.859 (Biomedical Research and Research Training) to E&E Bioclub LLC in Indianapolis, IN. The project aims to develop an all-in-one platform for intracellular overproduction of long, single-strand mRNA. This is intended to address challenges with current mRNA manufacturing methods, such as the cost and scalability constraints of in vitro transcription and the difficulty in...
The National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) awarded a $375,000 Project Grant (CFDA 93.859 Biomedical Research and Research Training) to Rowan University to develop a liquid chromatography-mass spectrometry (LC-MS) platform for rapid, real-time monitoring of targeted small molecule metabolites in biological systems. The project aims to create a sensor-like LC-MS system that can simultaneously monitor multiple analytes through miniaturization,...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) is funding the development of a Spotting-Free Nano-Oscillator Array (SFNOA) technology by Biosensing Instrument Inc., a for-profit company based in Tempe, Arizona. The SFNOA platform aims to enable high-throughput, label-free quantification of ligand binding kinetics to transmembrane proteins in their native states. The $349,566 award, with a...